Acetaminophen / Dextromethorphan / Diphenhydramine Dosage

Medically reviewed by Drugs.com. Last updated on Sep 20, 2023.

Usual Adult Dose for Cold Symptoms

Dextromethorphan 10 mg/ diphenhydramine 12.5 mg/ paracetamol 325 mg per 5 mL oral liquid: 10 mL every 4 to 6 hours
Maximum dose: 6 doses per 24 hours

Usual Adult Dose for Influenza

Dextromethorphan 10 mg/ diphenhydramine 12.5 mg/ paracetamol 325 mg per 5 mL oral liquid: 10 mL every 4 to 6 hours
Maximum dose: 6 doses per 24 hours

Usual Pediatric Dose for Cold Symptoms

Dextromethorphan 10 mg/ diphenhydramine 12.5 mg/ paracetamol 325 mg per 5 mL oral liquid:
12 years and older: 10 mL every 4 to 6 hours
Maximum dose: 6 doses per 24 hours

6 to under 12 years: 5 mL every 4 to 6 hours
Maximum dose: 5 doses per 24 hours

Usual Pediatric Dose for Influenza

Dextromethorphan 10 mg/ diphenhydramine 12.5 mg/ paracetamol 325 mg per 5 mL oral liquid:
12 years and older: 10 mL every 4 to 6 hours
Maximum dose: 6 doses per 24 hours

6 to under 12 years: 5 mL every 4 to 6 hours
Maximum dose: 5 doses per 24 hours

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Use with caution.

Precautions

CONTRAINDICATIONS:

• Current use of any other drug containing paracetamol.
• Current use of a monoamine oxidase inhibitor (MAOI) or use within 14 days of stopping a MAOI.
• Current use of any other drug containing diphenhydramine, including topical preparations.

Safety and efficacy have not been established in patients younger than 6 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer