Comparing Auvelity vs Spravato
Auvelity | Spravato |
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Auvelity (bupropion / dextromethorphan) | Spravato (esketamine) |
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Prescription only
Auvelity is an oral combination antidepressant tablet containing bupropion and dextromethorphan that has a novel way of working to treat adults with severe depression. Research has shown it is... View more |
Prescription only
Prescribed for Major Depressive Disorder, Depression. Spravato may also be used for purposes not listed in this medication guide. |
Related suggestions Major Depressive Disorder
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More about Auvelity (bupropion / dextromethorphan) | More about Spravato (esketamine) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Auvelity has an average rating of 8.3 out of 10 from a total of 96 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 9% reported a negative effect. |
Spravato has an average rating of 6.2 out of 10 from a total of 117 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 31% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: Auvelity side effects in more detail. |
See also: Spravato side effects in more detail. |
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Generic Availability | |||||||||||||||||
N/A |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Auvelity prices |
View all Spravato prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
N/A |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
30 hours |
12 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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Pregnancy Category | |||||||||||||||||
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 637 drugs are known to interact with Auvelity:
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A total of 294 drugs are known to interact with Spravato:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
August 18, 2022 |
N/A |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.