Acquired Von Willebrand Syndrome
Medically reviewed by Drugs.com. Last updated on Apr 2, 2024.
AMBULATORY CARE:
Acquired von Willebrand syndrome (AVWS)
is a blood disorder that causes heavy bleeding or bleeding that will not stop. AVWS develops later in life, usually because of some other illness or disease. AVWS may also develop if you do not have enough von Willebrand factor (VWF), or it does not work correctly. VWF is a protein that helps blood clot.
Signs and symptoms of AVWS:
- Bleeding too much or too long from wounds, after surgery, or after having a tooth pulled
- Bleeding from the gums or nose that happens often
- Bowel movements that are black or dark
- Urine that is pink or red
- Heavy monthly periods, or heavy bleeding when giving birth
Call your local emergency number (911 in the US) if:
- You have chest pain or tightness.
- You have trouble breathing.
- You have a seizure or faint.
Seek care immediately if:
- You cannot control your bleeding episodes, even after applying pressure.
- You have many large bruises or joint swelling.
- You vomit blood or have bloody or black bowel movements.
- You have blood in your urine.
Call your doctor or hematologist if:
- You feel tired and weak.
- You have a fever.
- You have nausea, are vomiting, or have a severe headache.
- You have questions or concerns about your condition or care.
Treatment:
AVWS cannot be cured. The goal of treatment is to prevent and control bleeding. You may need any of the following:
- Desmopressin helps your body make more VWF.
- Replacement therapy is concentrated VWF that is given through IV infusion.
- Immune globulin medicine is given as a shot or an IV infusion to make your immune system stronger. You may need immune globulins to treat or prevent an infection.
- Birth control pills may be given if you are female to increase VWF levels in your blood. This may also help control heavy monthly periods.
- Steroids may be given to decrease inflammation.
Manage a bleeding episode:
- Apply direct pressure to the bleeding area. Use a clean cloth. Hold pressure constantly for at least 10 to 15 minutes and until the bleeding stops. Place another cloth over the first cloth if it gets soaked with blood.
- Pinch the end of your nose during a nosebleed. Hold pressure constantly for 10 to 15 minutes. Breathe through your mouth and lean forward to keep blood from going down your throat.
- Rest when you have a nosebleed. Place 2 to 3 pillows behind your head when you are lying down. This will help you breathe easier. If you ever feel weak or dizzy, sit or lie down right away.
- Use extra pads during your monthly periods. Ask your healthcare providers about other ways to help control heavy menstrual bleeding.
Prevent bleeding episodes:
- Do not play contact sports, such as football or hockey. Contact sports increase your risk for bleeding or bruising. Ask your hematologist or healthcare provider which sports and activities are best for you.
- Do not use aspirin or NSAIDs, such as ibuprofen. These may thin your blood or increase your risk for bleeding. Ask your hematologist or provider before you take other over-the-counter medicines. Some may worsen your condition.
Follow up with your doctor or hematologist as directed:
You will need regular blood tests since VWF may change over time. Write down your questions so you remember to ask them during your visits.
© Copyright Merative 2024 Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.
Learn more about Acquired Von Willebrand Syndrome
Treatment options
Care guides
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.