Interferon Alfacon-1 use while Breastfeeding

Drugs containing Interferon Alfacon-1: Infergen

Interferon Alfacon-1 Levels and Effects while Breastfeeding

Summary of Use during Lactation

There are no data on the use of interferon alfacon-1 during breastfeeding. However, the amounts of the similar drugs, interferon alfa and interferon beta-1a, excreted into milk are very low. Any interferon in breastmilk is probably destroyed in the infant's gastrointestinal tract and not absorbed, except perhaps in neonates. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of the related endogenous interferon-gamma by an average about 10%.[1]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Possible Effects on Lactation

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

(Hepatitis C) Interferon Alfa

References

1. Ewaschuk JB , Unger S, O'Connor DL, Stone D, Harvey S, Clandinin MT et al. Effect of pasteurization on selected immune components of donated human breast milk. J Perinatol. 2011;31:593-8. PMID: 21330996

Interferon Alfacon-1 Identification

Substance Name

Interferon Alfacon-1

CAS Registry Number

118390-30-0

Drug Class

  • Immunologic Adjuvants

Administrative Information

LactMed Record Number

581

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2013-12-06

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

See Also...

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