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Ceftibuten use while Breastfeeding

Drugs containing Ceftibuten: Cedax

Ceftibuten Levels and Effects while Breastfeeding

Summary of Use during Lactation

Ceftibuten is acceptable to use during breastfeeding. Limited information indicates that single maternal doses of ceftibuten up to 200 mg produce low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally, disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush, has been reported with cephalosporins, but these effects have not been adequately evaluated.

Drug Levels

Maternal Levels. After a single 200 mg oral dose of ceftibuten in 6 women, the drug was undetectable (<1 mg/L) at any time up to 24 hours after the dose.[1]

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

References

1. Barr WH, Lin CC, Radwanski E et al. The pharmacokinetics of ceftibuten in humans. Diagn Microbiol Infect Dis. 1991;14:93-100. PMID: 2013216

Ceftibuten Identification

Substance Name

Ceftibuten

CAS Registry Number

97519-39-6

Drug Class

Antiinfective Agents

Antibacterial Agents

Cephalosporins

Administrative Information

LactMed Record Number

55

Last Revision Date

20130907

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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