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Leqvio for High Cholesterol User Reviews

Leqvio has an average rating of 7.3 out of 10 from a total of 22 reviews for the treatment of High Cholesterol. 50% of reviewers reported a positive experience, while 5% reported a negative experience.

Leqvio rating summary

7.3/10 average rating

22 ratings from 22 user reviews.

Compare all 295 medications used in the treatment of High Cholesterol.

10
27%
9
9%
8
14%
7
14%
6
18%
5
5%
4
9%
3
0%
2
0%
1
5%

Reviews for Leqvio

  • Mike
  • Taken for 1 to 2 years
  • September 24, 2023

"Update to my post on August 2023. 4 weeks after my 4th injection, I was diagnosed with a sterile UTI bladder infection. On top of that, I have had multiple night leg cramps and joint and muscle pains from head to toe. I told the doctor I will not be taking any more injections and I will go back to 5mg Crestor every third day. I can't find any information about how long it takes for Leqvio to get out of the system. Hopefully, I will feel better at the 6-month mark and pray no permanent damage was done. I was so hopeful since I had no initial symptoms, but it was not meant to last."

4 / 10
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47 Report
  • Linda
  • Taken for 1 to 6 months
  • February 9, 2024

"Had first dose. Have been experiencing leg cramps, not severe, wearing support hose helps a lot. The other thing I am experiencing is migraine headaches. Although the shot was given Dec. 14th, the headaches started the week of February 9th. Has anyone had this problem?"

8 / 10
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24 Report
  • chuck
  • Taken for 1 to 6 months
  • September 29, 2023

"Leqvio lowered my cholesterol to 128, but the side effects include shortness of breath, diarrhea, weight loss of 28 lbs in 6 months, chest pains, frequent urination, muscle cramps. I could barely walk and had to undergo several tests including a colonoscopy, angiogram, and lung examination. It was determined that all these symptoms were caused by the medication. Doctors have taken me off of Leqvio. It was effective, but I can't tolerate it."

6 / 10
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38 Report

Frequently asked questions

  • Hate...
  • Taken for less than 1 month
  • April 4, 2024

"I am on week 3 following the initial dose. Week 1 had minimal side effects: cough, a little sore muscles. Week 2 full-blown Bronchitis, cough, shortness of breath, absolute misery. Week 3 Bronchitis calming down, but now have extreme tiredness. I sleep 8-10 hours and still need a mid-afternoon nap. Before the injection, I'd sleep 6-9 hours and wake up well-rested and full of energy. I hope these side effects go away soon. If not, no more injections for me - Quality of life trumps this 'cure'."

5 / 10
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9 Report
  • Mike
  • Taken for 1 to 2 years
  • August 19, 2023

"Just had my 4th shot. After my second, I had labs drawn and all my numbers dropped by about 40%. HDL, LDL, Trigl, every level is perfect according to my doctor. Very pleased. No side effects at all. So glad because I tried every statin and all caused tremendous pain, especially in joints and feet. Cost covered by Medicare and Supplement. Male age 69."

10 / 10
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28 Report

Are you taking this medicine?

  • Mimi
  • Taken for 1 to 2 years
  • October 4, 2023

"My LDL went from 124 to 54 after the first shot. I have had trouble breathing a few times, which never happened before. But I think it's causing hair loss, and I noticed several people mentioned that, but it's not listed as a side effect. The shot itself is painful for a short while. Wish I knew for sure if it was causing my hair loss."

8 / 10
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18 Report
  • Tommy
  • Taken for 1 to 6 months
  • February 20, 2024

"Soon after taking my first injection, I experienced fatigue lasting several days. I also started seeing blood clots in my urine. I discontinued, but periodic blood clots continue sporadically. Had a cystoscopy and CT that were negative. My gums also started bleeding immediately afterwards. I would think twice about this “new” drug without much of a track record. It did dramatically reduce my numbers, but the bleeding was very concerning."

6 / 10
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8 Report

More FAQ

  • O R D
  • Taken for 6 months to 1 year
  • October 12, 2023

"Leqvio has done an amazing job at lowering LDL and total cholesterol. I have noticed muscular and joint pain, and a persistent cough since taking it. Also, shortness of breath on even very light activity levels. Other than that, it has done a great job at lowering cholesterol."

8 / 10
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14 Report
  • Jose
  • Taken for less than 1 month
  • May 15, 2024

"After about 4 days: nose bleed, sinusitis, sore lips and tongue. Feeling of exhaustion for a month. After 2 months, developed eczema and psoriasis on shins, and after a further week extremely itchy spots on trunk, arms, and legs. After month 1, cholesterol had reduced from 5.4 to 4.5."

7 / 10
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1 Report
  • brr
  • Taken for 1 to 6 months
  • May 7, 2024

"Week after second dose. So tired don't want to get up from chair. Stiff leg muscles. Pain in back and hips. The medicine works well, bad cholesterol went from 112 to 43 in one month 49 after three months. Thankful for that but side effects are hard to deal with. Questioning the third dose."

6 / 10
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0 Report
  • revric
  • Taken for 1 to 6 months
  • April 26, 2024

"The Leqvio injection was a brief stop at the cardiologist's office. Typical, brief shot in the back of the arm. Easy. They held me there for ~15 minutes to ensure no injection symptoms. The nurse administering the injection did it very well. No pain or discomfort. I don't have serum numbers yet so I am unable to speak to the effectiveness, but I wish all my meds could be this easy."

9 / 10
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0 Report
  • Divin...
  • Taken for 1 to 6 months
  • March 15, 2023

"I am having the most severe muscle pain and tight muscles I have ever had since I have been on Leqvio. Has anyone else had this?"

4 / 10
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78 Report
  • Anonymous
  • Taken for 1 to 6 months
  • May 8, 2023

"Side effects, hives, itching, pain with urination, headaches, dizziness, blurred vision and sweating"

1 / 10
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48 Report
  • Eliot...
  • Taken for 6 months to 1 year
  • April 3, 2024

"About a month after Leqvio shot, I get heartburn, nausea, belly cramps, fatigue. Numbers are good, but not liking the side effects. Anyone else having similar issues?"

7 / 10
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6 Report
  • David
  • Taken for 1 to 6 months
  • August 6, 2023

"Leqvio works very well to lower the LDL cholesterol, but I am having substantial weakness in my legs. No other side effects. Would hope there is some way to eliminate the weakness."

10 / 10
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17 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • May 6, 2023

"Took first dose in October 2022. Bad cholesterol was 105 Second does in January Bad cholesterol was 45 in February. Cardiologist was amazed!! Feel much better this summer"

10 / 10
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15 Report
  • jack
  • Taken for 1 to 6 months
  • February 29, 2024

"Massive drop in LDLs with Leqvio. Medication was prescribed by my cardiologist, and Medicare with Supplementals paid for its EXPENSIVE costs."

10 / 10
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2 Report
  • Thomas...
  • Taken for 2 to 5 years
  • January 1, 2024

"Worked for me, been taking it for a couple of years."

10 / 10
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2 Report
  • Mary
  • Taken for 6 months to 1 year
  • April 18, 2024

"Leqvio helped me lower my cholesterol levels significantly. I cannot take statins because of the bone and muscle pain. However, I have bone and muscle pain even with taking Leqvio."

9 / 10
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0 Report
  • Anonymous
  • April 15, 2024

"Lowest numbers I have ever had. Not aware of any side effects."

10 / 10
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0 Report
  • Eliot...
  • Taken for 1 to 2 years
  • May 22, 2024

"Had high hopes, but too many gastrointestinal side effects. Also muscle pain and stiffness. Lowers cholesterol but 2 months after the shot, I still have side effects."

7 / 10
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0 Report
  • roger...
  • Taken for 6 months to 1 year
  • May 19, 2024

"Not sure if this is related to Leqvio or not, however, since beginning the Leqvio regimen I have experienced an increased level of muscle and joint pain and reduced mobility."

6 / 10
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0 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.