Hydrate Side Effects

Generic name: dimenhydrinate

Medically reviewed by Drugs.com. Last updated on Jun 10, 2024.

Note: This document provides detailed information about Hydrate.

Applies to dimenhydrinate: oral solution, oral tablets, parenteral injection Side Effects associated with dimenhydrinate. Some dosage forms listed on this page may not apply specifically to the brand name Hydrate.

Applies to dimenhydrinate: oral solution, oral tablets, parenteral injection.

Side effects include:

Drowsiness, headache, blurred vision, tinnitus, dryness of the mouth and respiratory passages, incoordination, palpitation, dizziness, hypotension.

Paradoxical CNS stimulation in pediatric patients and occasionally in adults.

With IM injection: Pain at the injection site.

Because dimenhydrinate (the active ingredient contained in Hydrate) contains diphenhydramine, the possibility of other diphenhydramine-related adverse effects should also be considered.

For healthcare professionals

Applies to dimenhydrinate: compounding powder, injectable solution, oral liquid, oral tablet, oral tablet chewable.

General

The most frequently reported adverse reaction is drowsiness.^[Ref]

Cardiovascular

• Frequency not reported: Tachycardia^[Ref]

Dermatologic

• Frequency not reported: Skin rash^[Ref]

Gastrointestinal

• Frequency not reported: Dry mouth, epigastric distress, nausea^[Ref]

Genitourinary

• Frequency not reported: Difficult or painful urination^[Ref]

Metabolic

• Frequency not reported: Anorexia^[Ref]

Nervous system

• Frequency not reported: Drowsiness, dizziness, headache, excitation^[Ref]

Ocular

• Frequency not reported: Blurred vision^[Ref]

Other

• Frequency not reported: Lassitude^[Ref]

Psychiatric

• Frequency not reported: Nervousness, restlessness, insomnia^[Ref]

Respiratory

• Frequency not reported: Dry nose, dry throat, thickening of bronchial secretions^[Ref]

Further information

Hydrate side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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