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Hydrochlorothiazide / metoprolol Pregnancy and Breastfeeding Warnings

Brand names: Dutoprol, Lopressor HCT

Medically reviewed by Drugs.com. Last updated on Aug 4, 2023.

Hydrochlorothiazide / metoprolol Pregnancy Warnings

This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus.

US FDA pregnancy category: C

Animal studies have revealed evidence of decreased postnatal survival and increased postimplantation and fetal loss. There are no controlled data in human pregnancy.

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

See references

Hydrochlorothiazide / metoprolol Breastfeeding Warnings

A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.

Excreted into human milk: Yes (hydrochlorothiazide, metoprolol [in small amounts])

A mother taking metoprolol would transfer less than 1 mg/L to a breastfeeding infant.

See references

See also

References for pregnancy information

  1. (2022) "Product Information. Lopressor HCT (hydrochlorothiazide-metoprolol)." Novartis Pharmaceuticals

References for breastfeeding information

  1. (2022) "Product Information. Lopressor HCT (hydrochlorothiazide-metoprolol)." Novartis Pharmaceuticals

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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