Skip to main content

Can you take Mucinex and Nyquil together?

Medically reviewed by Carmen Pope, BPharm. Last updated on Feb 14, 2024.

Official answer

by Drugs.com

Yes, Mucinex and Nyquil can be taken together because they contain different ingredients, but Mucinex DM and Nyquil should not be taken together because they share a common ingredient, dextromethorphan. Instead of taking Mucinex DM and Nyquil together you should just take Nyquil.

Mucinex contains guaifenesin which is an expectorant and its main purpose is to thin out the mucus in your airways and relieve congestion in your lungs and chest. Mucinex DM contains dextromethorphan in addition to guaifenesin. Dextromethorphan is a cough suppressant.

Nyquil contains acetaminophen (relieves pain and fever), doxylamine (an antihistamine that will dry up nasal secretions and may also cause drowsiness to help sleep) and dextromethorphan.

References
  • Moran C. What's The Difference Between All The Many NyQuil Variations? Sept 4, 2014. Consumer Reports. https://www.consumerreports.org/consumerist/whats-the-difference-between-all-the-different-nyquil-variations/#:~:text=The%20active%20ingredients%20are%3A%20the,primary%20source%20of%20your%20sleepiness.

Read next

Some research suggests that Mucinex may help increase fertility by keeping the cervical mucus thin around the time of ovulation, which ensures sperm can travel freely through the cervix and helps with sperm survival. An increase in fertility can help increase your chances of becoming pregnant. Women with hostile mucus as the only cause of their infertility are the ones most likely to benefit from guaifenesin treatment. Continue reading

Mucinex products do not help to prevent or treat the COVID-19 virus itself, but might help relieve some of the symptoms of COVID, like chest congestion, cough, or headache. Select a product that targets only the symptoms you have. Continue reading

Yes, there are 4 Mucinex over-the-counter (OTC) daytime products that can help with your sore throat. Three products come as lozenges that contain hexylresorcinol and one is an oral spray with benzocaine. They all belong to the Mucinex InstaSoothe line of products. Continue reading

Related medical questions

Drug information

Related support groups

Medical Disclaimer