Does tramadol cause constipation?

Yes, tramadol can cause constipation and is one of the most common side effects with this drug. In studies, constipation was reported in up to 46% of patients. In some cases it may be severe. Call your healthcare provider if you have any tramadol symptoms that worry you.

Constipation is a well-known and expected side effect of opioid use. It should be addressed quickly to prevent further complications. Longer-term treatment has been shown to increase the frequency of constipation.

Use extra caution in older patients and monitor more closely. In studies, constipation resulted in discontinuation of treatment in 10% of those over 75 years of age.

The use of other drug therapies that lead to constipation, such as anticholinergic drugs, can worsen the constipating effect of tramadol. If you are not sure if you are taking other medicines that may worsen constipation, ask your doctor or pharmacist.

To learn more: Which drugs cause opioid-induced constipation?

Tramadol (Ultram) is commonly associated with other stomach (gastrointestinal) side effects such as:

• nausea (16% to 40%)
• vomiting (5% to 17%)
• dry mouth (5% to 13%)
• heartburn (1% to 13%)

Tramadol side effects (in more detail)

Related Questions

• Can you take tramadol with acetaminophen, ibuprofen, or aspirin?
• How much tramadol should I give my dog?
• Is tramadol stronger than codeine?

Bottom Line

• Tramadol can cause constipation in up to 46% of patients. Stomach side effects in general are common with tramadol.
• Constipation is a well-known side effect of opioid pain treatment, and it should be addressed quickly to prevent further complications.
• Call your doctor if you have constipation with opioid treatment. Ongoing constipation can lead to serious side effects.

This is not all the information you need to know about tramadol for safe and effective use. Review the full tramadol information here, and discuss this information and any questions with your doctor or other health care provider.