Depo-Medrol Drug Interactions
Currently displaying a list of 592 drugs known to interact with Depo-Medrol (methylprednisolone).
- 105 major drug interactions
- 449 moderate drug interactions
- 38 minor drug interactions
Medications known to interact with Depo-Medrol
Note: Showing generic names only.
A
- abametapir topical
- acarbose
- acebutolol
- acetazolamide
- acetohexamide
- adagrasib
- adalimumab
- adenovirus vaccine
- afamitresgene autoleucel
- albiglutide
- albuterol
- aldesleukin
- alefacept
- alemtuzumab
- aliskiren
- allogeneic processed thymus tissue
- alogliptin
- alprazolam
- aluminum carbonate
- aluminum hydroxide
- ambenonium
- amifampridine
- amiloride
- aminoglutethimide
- aminophylline
- amlodipine
- amobarbital
- amphotericin b
- amphotericin b cholesteryl sulfate
- amphotericin b lipid complex
- amphotericin b liposomal
- amprenavir
- anakinra
- anisindione
- anthrax vaccine adsorbed
- apalutamide
- aprepitant
- aprocitentan
- arformoterol
- armodafinil
- asciminib
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- aspirin
- atazanavir
- atenolol
- atezolizumab
- atracurium
- avacopan
- axicabtagene ciloleucel
- azilsartan medoxomil
B
- baricitinib
- bcg
- bcg vaccine
- belzutifan
- bempedoic acid
- benazepril
- bendroflumethiazide
- benzthiazide
- berotralstat
- betaxolol
- bexagliflozin
- bexarotene
- bifidobacterium infantis
- bisacodyl
- bisoprolol
- bitolterol
- boceprevir
- bosentan
- brewer's yeast
- brexucabtagene autoleucel
- bromfenac
- bumetanide
- bupropion
- butabarbital
- butalbital
C
- calaspargase pegol
- calcium carbonate
- canagliflozin
- canakinumab
- candesartan
- candida albicans extract
- capivasertib
- capreomycin
- captopril
- carbamazepine
- carteolol
- carvedilol
- casanthranol
- cascara sagrada
- castor oil
- cat's claw
- celecoxib
- cemiplimab
- ceritinib
- certolizumab
- chikungunya vaccine, live (cvx 317)
- chloramphenicol
- chlorothiazide
- chlorotrianisene
- chlorpropamide
- chlorthalidone
- cholera vaccine
- cholera vaccine, live
- cholestyramine
- choline salicylate
- ciltacabtagene autoleucel
- cinoxacin
- ciprofloxacin
- cisatracurium
- cisplatin
- cladribine
- clarithromycin
- clevidipine
- clonidine
- cobicistat
- coccidioidin skin test
- colesevelam
- colestipol
- conivaptan
- conjugated estrogens
- conjugated estrogens topical
- cosyntropin
- COVID-19 mRNA (Moderna) vaccine
- COVID-19 mRNA (Pfizer) vaccine
- cyclosporine
D
- dabrafenib
- dapagliflozin
- daprodustat
- darunavir
- dasatinib
- deferasirox
- dehydroepiandrosterone
- delafloxacin
- delavirdine
- dengue vaccine
- denosumab
- deserpidine
- desirudin
- desmopressin
- deucravacitinib
- diazepam
- diazoxide
- dichlorphenamide
- diclofenac
- dicumarol
- dienestrol topical
- diethylstilbestrol
- diflunisal
- digitoxin
- digoxin
- dihydroxyaluminum sodium carbonate
- diltiazem
- dimethyl fumarate
- dinutuximab
- diroximel fumarate
- disopyramide
- dostarlimab
- doxacurium
- doxazosin
- dulaglutide
- durvalumab
- duvelisib
E
- echinacea
- edrophonium
- efalizumab
- efavirenz
- empagliflozin
- enalapril
- enalaprilat
- encorafenib
- enoxacin
- enzalutamide
- eplerenone
- eprosartan
- erlotinib
- ertugliflozin
- erythromycin
- esterified estrogens
- estradiol
- estradiol topical
- estramustine
- estrone
- estropipate
- estropipate topical
- etanercept
- ethacrynic acid
- ethinyl estradiol
- ethotoin
- etodolac
- etrasimod
- etravirine
- exenatide
F
- fedratinib
- felodipine
- fenoldopam
- fenoprofen
- fexinidazole
- fingolimod
- fluconazole
- fluoxymesterone
- fluphenazine
- flurbiprofen
- fluvoxamine
- formoterol
- fosamprenavir
- fosaprepitant
- foscarnet
- fosinopril
- fosphenytoin
- fostamatinib
- furosemide
G
- galantamine
- gallium citrate ga-67
- gatifloxacin
- gemifloxacin
- gepirone
- glimepiride
- glipizide
- glyburide
- glycerin
- glycerol phenylbutyrate
- golimumab
- grepafloxacin
- guanabenz
- guanadrel
- guanethidine
- guanfacine
H
- haemophilus b conjugate (hboc) vaccine
- haemophilus b conjugate (prp-omp) vaccine
- haemophilus b conjugate (prp-t) vaccine
- hepatitis a adult vaccine
- hepatitis a pediatric vaccine
- hepatitis b adult vaccine
- hepatitis b pediatric vaccine
- histoplasmin
- human papillomavirus vaccine
- hyaluronidase
- hydralazine
- hydrochlorothiazide
- hydroflumethiazide
I
- ibuprofen
- idecabtagene vicleucel
- idelalisib
- imatinib
- indacaterol
- indapamide
- indinavir
- indium oxyquinoline in-111
- indomethacin
- infliximab
- influenza virus vaccine, h1n1, inactivated
- influenza virus vaccine, h1n1, live
- influenza virus vaccine, h5n1
- influenza virus vaccine, inactivated
- influenza virus vaccine, live
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- iohexol
- iomeprol
- iopamidol
- ipilimumab
- irbesartan
- isavuconazonium
- isoetharine
- isoniazid
- isoproterenol
- isotretinoin
- isradipine
- itraconazole
- ivacaftor
J
K
L
- labetalol
- lactitol
- lactobacillus acidophilus
- lactobacillus reuteri
- lactobacillus rhamnosus
- lactobacillus rhamnosus gg
- lactulose
- lapatinib
- larotrectinib
- lefamulin
- leflunomide
- lenacapavir
- lenvatinib
- letermovir
- levalbuterol
- levamlodipine
- levofloxacin
- levoketoconazole
- licorice
- lifileucel
- linagliptin
- liraglutide
- lisinopril
- lisocabtagene maraleucel
- lixisenatide
- lomefloxacin
- lonafarnib
- lonapegsomatropin
- lorlatinib
- losartan
- lyme disease vaccine
M
- macimorelin
- magaldrate
- magnesium citrate
- magnesium hydroxide
- magnesium oxide
- magnesium salicylate
- magnesium sulfate
- mavacamten
- mavorixafor
- measles virus vaccine
- meclofenamate
- mefenamic acid
- meloxicam
- meningococcal conjugate vaccine
- meningococcal group acwy conjugate-group b vaccine (cvx 316)
- meningococcal group B vaccine
- meningococcal polysaccharide vaccine
- mephenytoin
- mephobarbital
- metaproterenol
- metformin
- methazolamide
- methotrexate
- methyclothiazide
- methyldopa
- methyltestosterone
- metocurine
- metolazone
- metoprolol
- metrizamide
- mibefradil
- midazolam
- mifepristone
- miglitol
- mineral oil
- minoxidil
- mitotane
- mivacurium
- mixed respiratory vaccine
- mobocertinib
- modafinil
- moexipril
- monomethyl fumarate
- moxifloxacin
- mumps skin test antigen
- mumps virus vaccine
N
- nabumetone
- nadofaragene firadenovec
- nadolol
- nalidixic acid
- nandrolone
- naproxen
- natalizumab
- nateglinide
- nebivolol
- nefazodone
- nelfinavir
- neostigmine
- nevirapine
- nicardipine
- nifedipine
- nilotinib
- nintedanib
- nisoldipine
- nitroprusside
- nivolumab
- norfloxacin
O
- ocrelizumab
- ofloxacin
- olmesartan
- olutasidenib
- omacetaxine
- omaveloxolone
- omidubicel
- osilodrostat
- oxandrolone
- oxaprozin
- oxcarbazepine
- oxymetholone
- ozanimod
P
- pacritinib
- pancuronium
- patiromer
- pegaspargase
- pembrolizumab
- penbutolol
- pentobarbital
- perindopril
- pertussis, acellular
- phenobarbital
- phenolphthalein
- phenylbutazone
- phenytoin
- physostigmine
- pindolol
- pioglitazone
- pipecuronium
- pirbuterol
- piroxicam
- pirtobrutinib
- pitolisant
- plague vaccine
- pneumococcal 13-valent vaccine
- pneumococcal 15-valent conjugate vaccine
- pneumococcal 20-valent conjugate vaccine
- pneumococcal 21-valent conjugate vaccine
- pneumococcal 23-polyvalent vaccine
- pneumococcal 7-valent vaccine
- poliovirus vaccine, inactivated
- poliovirus vaccine, live, trivalent
- polyethylene glycol 3350
- polythiazide
- ponesimod
- posaconazole
- pralsetinib
- pramlintide
- prazosin
- primidone
- propranolol
- pyridostigmine
Q
R
- rabies vaccine, human diploid cell
- rabies vaccine, purified chick embryo cell
- racepinephrine
- ramipril
- rapacuronium
- rauwolfia serpentina
- repaglinide
- repotrectinib
- reserpine
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rilonacept
- ritlecitinib
- ritodrine
- ritonavir
- rivastigmine
- rocuronium
- rofecoxib
- roflumilast
- romosozumab
- rosiglitazone
- rotavirus vaccine
- rsv vaccine pref3, recombinant
- rsv vaccine, mrna
- rsv vaccine, pref a-pref b, recombinant
- rubella virus vaccine
- rucaparib
- rufinamide
S
- saccharomyces boulardii lyo
- salmeterol
- salsalate
- saquinavir
- sars-cov-2 (covid-19) ad26 vaccine, recombinant
- sars-cov-2 (covid-19) chadox1 vaccine, recombinant
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
- sars-cov-2 (covid-19) nvx-cov2373 vaccine, recombinant
- sars-cov-2 (covid-19) rs-nanoparticle vaccine, recombinant
- sars-cov-2 mrna (tozinameran 5y-11y) vaccine
- sars-cov-2 mrna (tozinameran 6m-4y) vaccine
- sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine
- sars-cov-2 mrna (tozinameran) vaccine
- sars-cov-2 mrna-1273 (6m-5y) vaccine
- sars-cov-2 mrna-1273 (6y-11y) vaccine
- sars-cov-2 mrna-1273 (booster only) vaccine
- sars-cov-2 nvx-cov2373 vaccine, recomb (cvx 313)
- sars-cov-2 pres dtm (booster only) vaccine, recombinant
- saxagliptin
- secobarbital
- selpercatinib
- semaglutide
- senna
- siponimod
- sipuleucel-T
- sirolimus
- sitagliptin
- skin test antigens, multiple
- smallpox and mpox vaccine
- smallpox vaccine
- sodium bicarbonate
- sodium iodide i-123
- sodium iodide-i-131
- sodium phenylbutyrate
- sodium polystyrene sulfonate
- sodium salicylate
- sodium thiosalicylate
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotagliflozin
- sotorasib
- sparfloxacin
- spironolactone
- stanozolol
- staphage lysate (spl)
- stiripentol
- streptococcus salivarius
- succinylcholine
- sulindac
T
- tacrolimus
- talimogene laherparepvec
- tazemetostat
- telaprevir
- telbivudine
- telithromycin
- telmisartan
- telotristat
- temsirolimus
- terazosin
- terbutaline
- teriflunomide
- testosterone
- testosterone topical
- tetanus toxoid
- thalidomide
- theophylline
- tick-borne encephalitis (inactivated) pediatric vaccine
- tick-borne encephalitis (inactivated) vaccine
- ticlopidine
- timolol
- tirzepatide
- tofacitinib
- tolazamide
- tolbutamide
- tolmetin
- toripalimab
- torsemide
- trandolapril
- triamterene
- triazolam
- trichlormethiazide
- trichophyton skin test
- trimethaphan camsylate
- trofinetide
- troglitazone
- troleandomycin
- trovafloxacin
- tuberculin purified protein derivative
- tubocurarine
- tucatinib
- typhoid vaccine, inactivated
- typhoid vaccine, live
U
V
- valdecoxib
- valsartan
- varicella virus vaccine
- vecuronium
- verapamil
- vigabatrin
- vitamin e
- voclosporin
- vorasidenib
- voriconazole
- voxelotor
W
Y
Z
- zavegepant
- zidovudine
- zinc acetate
- zinc chloride
- zinc gluconate
- zinc sulfate
- zoster vaccine live
- zoster vaccine, recombinant
Depo-Medrol alcohol/food interactions
There are 3 alcohol/food interactions with Depo-Medrol (methylprednisolone).
Depo-Medrol disease interactions
There are 23 disease interactions with Depo-Medrol (methylprednisolone) which include:
- infections
- prematurity
- (+) tuberculin test
- cirrhosis
- depression/psychoses
- diabetes
- electrolyte imbalance
- fluid retention
- GI perforation
- hyperadrenocorticalism
- hyperlipidemia
- hypothyroidism
- liver disease
- MI
- myasthenia gravis
- myopathy
- ocular herpes simplex
- ocular toxicities
- osteoporosis
- PUD
- scleroderma
- strongyloidiasis
- thromboembolism
More about Depo-Medrol (methylprednisolone)
- Depo-Medrol consumer information
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (19)
- Side effects
- Dosage information
- During pregnancy
- Drug class: glucocorticoids
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.