Ragweed Pollen Allergen Extract Dosage

Medically reviewed by Drugs.com. Last updated on Jun 20, 2023.

Applies to the following strengths: 12 Amb a 1-U

Usual Adult Dose for:

Allergic Rhinitis

Additional dosage information:

Renal Dose Adjustments
Liver Dose Adjustments
Precautions
Dialysis
Other Comments

Usual Adult Dose for Allergic Rhinitis

One tablet sublingually once a day.

Comments:

Initiate treatment at least 12 weeks before the expected onset of each ragweed pollen season and continue treatment throughout the season.

Use: Treatment of short ragweed pollen-induced allergic rhinitis, with or without conjunctivitis, confirmed by positive skin test or in vitro testing for pollen-specific IgE antibodies for short ragweed pollen.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

US BOXED WARNING:

Short ragweed allergen can cause life-threatening allergic reactions such as anaphylaxis and severe laryngopharyngeal restriction.
Do not administer short ragweed allergen to patients with severe, unstable or uncontrolled asthma.
Observe patients in the office for at least 30 minutes following the initial dose.
Prescribe auto-injectable epinephrine, instruct and train patients on its appropriate use, and instruct patients to seek immediate medical care upon its use.
May not be suitable for patients with certain underlying medical conditions that may reduce their ability to survive a serious allergic reaction.
May not be suitable for patients who may be unresponsive to epinephrine or inhaled bronchodilators, such as those taking beta-blockers.

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

Administer the first dose in a healthcare setting under the supervision of a physician with experience in the field.
After receiving the first dose, observe the patient for at least 30 minutes to monitor for signs or symptoms of a severe systemic or a severe local allergic reaction.
Allow the tablet to remain under the tongue until completely dissolved. Do not swallow for at least 1 minute.
Wash hands after handling the tablet.
Do not take the tablet with food or beverage. Food or beverage should not be taken for at least 5 minutes after taking the tablet.
Prescribe auto-injectable epinephrine to patients and instruct them in the proper use of emergency self-injection of epinephrine.

Storage requirements: