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Gadobutrol Dosage

Medically reviewed by Drugs.com. Last updated on Apr 30, 2024.

Applies to the following strengths: 604.72 mg/mL

Usual Adult Dose for CNS Magnetic Resonance Imaging

0.1 mL/kg body weight (0.1 mmol/kg) IV bolus injection
Comments: Administer manually or by power injector at a flow rate of approximately 2 mL/second. Refer to manufacturer product information to determine volume to be administered.

Use: Indicated for use with MRI to detect and visualize areas with disrupted blood brain barrier (BBB) and/or abnormal vascularity of the central nervous system.

Usual Adult Dose for Diagnostic

0.1 mL/kg body weight (0.1 mmol/kg) IV bolus injection
Comments: Administer manually or by power injector at a flow rate of approximately 2 mL/second. Refer to manufacturer product information to determine volume to be administered.

Use: Indicated for use with MRI to assess the presence and extent of malignant breast disease.

Usual Pediatric Dose for CNS Magnetic Resonance Imaging

0.1 mL/kg body weight (0.1 mmol/kg) IV bolus injection
Comments: Administer manually or by power injector at a flow rate of approximately 2 mL/second. Refer to manufacturer product information to determine volume to be administered.

Use:

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

Data not available

Precautions

US BOXED WARNING(S):
NEPHROGENIC SYSTEMIC FIBROSIS (NSF):


CONTRAINDICATIONS:

Consult WARNINGS section for additional precautions.

Dialysis

Hemodialysis: May consider the prompt initiation of hemodialysis following the administration of the drug in order to enhance elimination.
Peritoneal dialysis: Data not available

Other Comments

Administration advice:


Storage requirements:

Reconstitution/preparation techniques: Refer to manufacturer product information

IV compatibility: Do not mix or co-infuse with other IV medications.

General: False positive detection rates for breasts with malignancy ranged from 39% to 53%.

Monitoring:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.