Depo-Medrol Alternatives Compared
Depo-Medrol | Sulfasalazine | Methotrexate |
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Depo-Medrol (methylprednisolone) | Sulfasalazine | Methotrexate |
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Prescription only
Prescribed for Allergic Rhinitis, Asthma, Adrenogenital Syndrome, Allergies, Asthma - Maintenance, Asthma - acute, Dermatologic Lesion, Gout - Acute, Immunosuppression, Inflammatory Conditions... View more |
Prescription only
Prescribed for Alopecia, Crohn's Disease, Crohn's Disease - Active, Inflammatory Bowel Disease, Crohn's Disease - Maintenance, Juvenile Rheumatoid Arthritis, Lymphocytic Colitis, Psoriatic Arthritis... View more |
Prescription only
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
Related suggestions Rheumatoid Arthritis
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More about Depo-Medrol (methylprednisolone) | More about Sulfasalazine | More about Methotrexate | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Depo-Medrol has an average rating of 5.8 out of 10 from a total of 19 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 44% reported a negative effect. |
Sulfasalazine has an average rating of 6.0 out of 10 from a total of 192 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 34% reported a negative effect. |
Methotrexate has an average rating of 6.6 out of 10 from a total of 330 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 23% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Depo-Medrol side effects in more detail. |
See also: sulfasalazine side effects in more detail. |
See also: methotrexate side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Depo-Medrol prices |
View all sulfasalazine prices |
View all methotrexate prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
Other methylprednisolone brands include: Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack, Solu-Medrol | Azulfidine, Azulfidine EN-tabs | Jylamvo, Methotrexate LPF Sodium, Otrexup, Rasuvo, Trexall, Xatmep | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
3.5 hours |
10 hours |
15 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category C
Risk cannot be ruled out
Excluding First Trimester
Category D
Positive evidence of risk
First Trimester See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 588 drugs are known to interact with Depo-Medrol:
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A total of 258 drugs are known to interact with sulfasalazine:
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A total of 695 drugs are known to interact with methotrexate:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||||||||||
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First Approval Date | ||||||||||||||||||||||||||
May 27, 1959 |
June 20, 1950 |
December 07, 1953 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.