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Sulfamethoxazole / trimethoprim User Reviews & Ratings (Page 5)

Brand names: Bactrim, Bactrim DS, Septra, Co-trimoxazole, SMZ-TMP DS, Septra DS, Bactrim Pediatric, Bactrim IV Sulfatrim Pediatric Bethaprim Bethaprim Pediatric …show all brand names

Sulfamethoxazole / trimethoprim has an average rating of 4.9 out of 10 from a total of 1,700 reviews on Drugs.com. 34% of reviewers reported a positive experience, while 47% reported a negative experience.

Reviews for Sulfamethoxazole / trimethoprim

  • Anonymous
  • October 21, 2009

Bactrim (sulfamethoxazole / trimethoprim) for Bacterial Skin Infection "I took Bactrim for a bacterial infection under my skin, on my face, that resulted in many cystic like bumps. They were so painful. After taking the medicine for just a few days, the swelling and pain went away and the bumps cleared up. I would take this medicine again."

9 / 10
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74 Report
  • Kadi
  • January 17, 2020

Bactrim (sulfamethoxazole / trimethoprim) for Bacterial Infection "My daughter was contaminated with stenotrophomonas maltophilia bacteria during a pleural drainage procedure and a year ago and for a year the bacteria has been treated with sulfamethoxazole/trimethoprim (TMPX), the bacteria became MDR after nine months of continuous treatment and my daughter developed acute renal failure after the overuse of this antibiotic."

1 / 10
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30 Report
  • JessG
  • May 19, 2014

Bactrim DS (sulfamethoxazole / trimethoprim) for Urinary Tract Infection "Felt mild relief, Doc said it should be gone in 3 days gave me enough to take it for 5 days in case it was not gone. I also experienced fevers and achiness. Not pleasant. Everyday I had discomfort and today I am out of it and feel terrible with my urinary tract symptoms again."

1 / 10
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56 Report

Frequently asked questions

  • BL fl...
  • Taken for less than 1 month
  • April 4, 2014

Bactrim (sulfamethoxazole / trimethoprim) for Bacterial Skin Infection "I was first prescribed Augmentin for an infection from a puncture wound near the nail bed of my thumb. It made me feel like I was suffering from morning sickness and did not work. Next I got Flagyl and Bactrim. The culture showed the Staph was sensitive to Bactrim and the wound is SO much better! Yes, there are some side effects (for me, insomnia but I don't know if that is Flagyl or Bactrim) but it is so much better than losing my finger! I also took Florastor with the medication to reduce intestinal upset and experienced none."

10 / 10
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56 Report
  • cano
  • Taken for less than 1 month
  • September 9, 2018

SMZ-TMP DS (sulfamethoxazole / trimethoprim) for Urinary Tract Infection "I had smelly urine but not the usual symptoms of UTI, but doc put me on this and by 4th day still had problem and felt sick - listless, not able to eat, stomach felt like it was FULL and heavy. By day 8 of taking it my son convinced me to stop med. I did and felt a bit better but it is now a month later and I have lost 14 lbs and barely able to stomach any food. Almost throw up when even thinking about eating! Have to force myself to eat--not at all happy!!!!!"

1 / 10
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36 Report

Are you taking this medicine?

  • Sunny
  • June 15, 2020

Bactrim (sulfamethoxazole / trimethoprim) for Acne "I hope this helps for anyone who is wanting to take Bactrim I got prescribed this by my dermatologist about a year and a half ago and it’s worked wonders! Everyone’s bodies react different to medications, but from my experience I can honestly say that It’s cleared up my acne completely and I had no side affects what so ever."

10 / 10
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27 Report
  • Anony...
  • Taken for less than 1 month
  • April 10, 2019

SMZ-TMP DS (sulfamethoxazole / trimethoprim) for Urinary Tract Infection "I was prescribed sulfamethoxazole and trimethoprim (SMZ/TMP) twice a day for 7 days for a UTI. I have one pill left, almost all the symptoms are gone. The first day I took the pill I was extremely sleepy. Every day after that I had a horrible headache in the back of my head and a stiff neck that came and went every few hours, also brought on by light sensitivity. Nausea, out of breathe at times, cold sweat on exertion & jittery."

2 / 10
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33 Report
  • Scooter
  • Taken for less than 1 month
  • January 30, 2020

Bactrim DS (sulfamethoxazole / trimethoprim) for Bacterial Infection "Started on this sulfate antibiotic Bactrim 2 days ago for an infected sebaceous cyst. Several hours after taking first pill I developed a 102°, fever, splitting headache, muscle aches....I thought I was coming down with the flu. The second day the same thing happened....fever, muscle aches, severe headache again.. Took some Tylenol and crawled into bed for the entire afternoon. I’m not going to take tonight’s pill, and call doctor in the morning for a different antibiotic. I’ve never had reactions like this to any antibiotics I have taken in the past."

1 / 10
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29 Report
  • Anonymous
  • May 26, 2010

SMZ-TMP DS (sulfamethoxazole / trimethoprim) for Urinary Tract Infection "I would get a urinary tract infection when I had sex. To control the situation my doctor prescribed SMZ-TMP DS. I took one or 2 a day for years. As long as I took the pills I was not bothered with a UTI. Miss a day or 2, and UTI. Worked wonderful. "

10 / 10
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70 Report
  • Kitty...
  • May 10, 2014

Bactrim (sulfamethoxazole / trimethoprim) for Urinary Tract Infection "I was prescribed Bactrim and felt worse right away. After reading the side effects, I told myself that what I was feeling was normal. I took the prescribed dosage (2 per day) for 5 days, feeling even worst on the 5th day - shaky, diarrhea, headache, nervousness, unable to sleep. Then after some research, I discovered that there also were interaction side effects with my blood pressure medications. "

6 / 10
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54 Report
  • Anonymous
  • July 11, 2014

Bactrim (sulfamethoxazole / trimethoprim) for Acne "If you just started this medicine I know you're probably feeling bad about you acne. BUT LISTEN Bactrim works from the inside out and if you breakout in the first few weeks that's fine stick with it because soon your skin will be clear and Bactrim will help stop breakouts from ever happening in the first place soon! Cleared my hormonal acne. I rarely get a pimple and I had moderate to server acne and it was a life saver! Your acne will be cleared in just a few months. I suggest using a topical gel as well. Hang in there it helped me during a rough time in just 3 1/2 months I had a clear face, just a few acne marks on my cheeks only thing that stinks is I'm scared to go off the antibiotic and have a repulse of acne. But I suggest this!"

9 / 10
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53 Report
  • Coach
  • Taken for less than 1 month
  • February 1, 2019

Sulfatrim (sulfamethoxazole / trimethoprim) for Bacterial Infection "MENTAL HEALTH WARNING: Even though it was the only drug working on my Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA), it has rare chance of causing significant psychosis or extreme mood disorder. I should have stopped taking it sooner, but it after two other drugs, I wanted it to work. If you have any symptoms of mood changes, STOP taking immediately. There have been cases of young adults not living thought their psychotic episode. I'm older, so I was able to realize my thoughts were not reality. Even when I thought reality was a delusion and my spouse of 20 years may not be real."

3 / 10
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33 Report
  • LeeOz
  • Taken for less than 1 month
  • June 30, 2019

Bactrim DS (sulfamethoxazole / trimethoprim) for Urinary Tract Infection "Fought a uti for over a week and finally gave up and went to the doctor earlier today. He prescribed Bactrim DS twice a day for 10 days and within an hour of my first dose the pain was gone. I’d hardly been able to leave the bathroom for almost a full day and all it took was one pill for me not to be absolutely miserable. I was an idiot for waiting and have had no unpleasant side effects."

10 / 10
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31 Report
  • Aut
  • Taken for less than 1 month
  • March 14, 2018

Bactrim DS (sulfamethoxazole / trimethoprim) for Urinary Tract Infection "If you're sick, meds typically have at least one side effect you'll experience. Its a prescription drug, not a miracle homeopathic treatment found in nature. You need to follow instructions and be aware of the warnings given. Ex: DON'T DRINK ALCOHOL during the course of the med. You NEED TO EAT SOMETHING with most meds, and drinking lots of water (way more than normal) is important too. I don't eat/drink water enough on a regular basis, and I love alcohol but, if I'm on a med, I alter my lifestyle to relieve symptoms of an infection I felt were bothersome enough to go to the drs in the first place. I've had no issues with bactrim/sulfa thankfully, and those who have might want to find out if they are allergic to it prior to writing a bad review. Its a VERY common drug allergy that shouldn't sway the opinions of those not allergic. If you happen to have severe side effects from this, or any, med please find out if you are allergic first and consider it a personal learning opportunity."

10 / 10
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37 Report
  • Anonymous
  • Taken for less than 1 month
  • September 1, 2020

Bactrim (sulfamethoxazole / trimethoprim) for Bacterial Infection "I am 30. I recently had a vasectomy which caused an infection while healing. Doctor prescribed Bactrim. I noticed after my nightly dosage, I would constantly wake up like I previously would when having an anxiety attack. I thought it was just due to outside stress but after reading this page I see it may have been increased by this medication. I wish I would have known sooner. Bactrim helped with my ailments but also made me use the last of my emergency Xanax in the process."

9 / 10
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25 Report
  • Gidget
  • Taken for less than 1 month
  • October 30, 2019

Bactrim DS (sulfamethoxazole / trimethoprim) for Urinary Tract Infection "Bactrim DS taken twice a day has been effective for each UTI I’ve had. It covers a resistant strain of E.Coli and has been effective all times I’ve taken it. I just make sure to eat a meal prior to taking it and I’m fine."

10 / 10
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29 Report
  • Liv
  • Taken for less than 1 month
  • July 24, 2023

Bactrim (sulfamethoxazole / trimethoprim) for Bacterial Skin Infection "I was prescribed Bactrim for a skin infection caused by an ingrown toenail. My podiatrist removed it, then put me on Bactrim DS (double strength) 2x daily for 2 weeks. After reading reviews here, I was terrified to take the first dose. I took it on an empty stomach because anxiety left me with no appetite. I drank plenty of water. Not one side effect. No nausea, no diarrhea, no insomnia, no sleepiness, no increased anxiety, no itchiness, nothing. The only thing was a mild headache on day two; however, I am prone to migraines so that could’ve been the norm with or without Bactrim. Some Excedrin worked, I haven’t had another headache since. I noticed my toe looking so much better with less pain by day 2 on Bactrim. I took one around 7 am, then a probiotic supplement around noon, followed by my second dose at 7 pm. People come here more when something goes wrong than when it works. That’s why I wanted to leave this review after a great experience."

10 / 10
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8 Report
  • WishI...
  • Taken for less than 1 month
  • June 2, 2022

Bactrim (sulfamethoxazole / trimethoprim) for Bacterial Skin Infection "I have severe medical anxiety thanks to terrible reactions to medications that started after a surgery. I’ve been on too many that made me feel absolutely crazy and had terrible side effects. I made the mistake of reading these reviews before starting Bactrim and was absolutely terrified. I took the first pill and immediately knew I was going to die and had terrible anxiety about this reaction I was going to have. But, guess what? I was FINE! I just took my last dose of a 7 day course and the only issue I had was making the mistake of going in the sun. I ended up burning a lot quicker than normal (there’s a warning for that). In fact, it had a pro to it… turns out it also helped my never ending stomach issues. Don’t let the other reviews scare you. As someone else said, most people only take the time to write reviews after a negative experience. That’s why I decided to start reviewing my positive ones."

10 / 10
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15 Report
  • Cigma
  • July 14, 2008

Bactrim (sulfamethoxazole / trimethoprim) for Sinusitis "After three days of perscribed use of the generic bactrim, my headaches and nasal discharge have decrease dramatically. Side Effects, insomnia (reason I am writing this review), pain in jaw and throat if not taken with ample water."

8 / 10
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71 Report
  • none
  • April 13, 2012

Bactrim DS (sulfamethoxazole / trimethoprim) for Urinary Tract Infection "I also had similar experiences and side effects like lethargy, shaking, confusion slightly, severe fatigue, headaches, aches and pains, but kept taking the medicine anyway because the pain of a urinary tract infection is much much worse. I'd rather suffer for a short time with these symptoms then suffer with a bladder infection."

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58 Report
  • Anonymous
  • December 20, 2011

Bactrim (sulfamethoxazole / trimethoprim) for Bacterial Infection "This was not right for me. I had a severe reaction while taking this and had to go to the emergency room. Racing/irregular heartbeat, nausea, shaky, legs felt weird, red blotches, slurring speech, red eyes, feverish and generally felt very unwell. "

1 / 10
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58 Report
  • Linds...
  • Taken for less than 1 month
  • June 22, 2014

Bactrim (sulfamethoxazole / trimethoprim) for Kidney Infections "Took this medicine for a horrible horrible HORRIBLE kidney infection. Worked within 2 days and cleared up all of my symptoms, which was such a relief. I was told to finish off the bottle by my doctor, and the next day I developed a horrible case if the hives. I stopped taking the medicine immediately, but the hives stuck around for another 3 days. What a miserable week! So, Bactrim worked wonders for my kidney infection, but little did I know I was severely allergic to it. Take with caution."

5 / 10
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49 Report
  • Jai...
  • Taken for less than 1 month
  • January 26, 2016

Bactrim (sulfamethoxazole / trimethoprim) for Urinary Tract Infection "I'm currently on bactrim, first day taking the medication and I saw an immediate difference. My Uti's are horrible, I'm normally awaken from my sleep, as they hurt that bad. I'm up for hours on hours sitting on the toilet due to the urge. Bactrim is helping this a lot. Also I see a lot of people are feeling sick while taking this medicine, my doctor recommends that I take the medicine with food, hope this helps you guys in the future if you're experiencing sickness."

10 / 10
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43 Report
  • Watts
  • Taken for less than 1 month
  • April 22, 2020

Bactrim (sulfamethoxazole / trimethoprim) for Bacterial Skin Infection "Was prescribed bactrim for a 'possible' infection in my leg from varicose veins. 2 pills a day for 10 days. Worst medication. Felt fine with the first pill, after the second pill I started to have bladder issues. Was peeing constantly, bladder felt heavy. Felt like I had to go after I just went. Was checked for a UTI, don't have one. Only took 2 pills and stopped. It has also caused headaches, my abdominal muscles feel weaker, loss of appetite. I must have been allergic or something.. Won't ever take this again."

1 / 10
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25 Report
  • Ashxl...
  • Taken for less than 1 month
  • November 16, 2017

Bactrim (sulfamethoxazole / trimethoprim) for Kidney Infections "I was a bit of a moron and let a UTI go for too long. I had pain on and off for a few months in my back. Pee was cloudy, frequent urination..all that good stuff but two days ago I woke up and felt absolutely terrible. I was so nauseous, couldn’t eat anything, awful headache, chills and the worst back pain I had ever felt. I went to Dr and she wrote this for me. I took two pills yesterday and already today I feel a 100x’s better. I don’t believe it is for everyone obviously due to the mixed reviews and my mother had taken it before and it had awful effects on her as well but I do believe it’s worth trying because for me it’s been wonderful. I couldn’t even bend over yesterday and today all I have is slight dull pain in my back.Worked perfect"

10 / 10
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35 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.