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Semaglutide for Diabetes, Type 2 User Reviews (Page 5)

Brand names: Ozempic, Wegovy, Rybelsus

Semaglutide has an average rating of 6.3 out of 10 from a total of 1082 reviews for the treatment of Diabetes, Type 2. 49% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Semaglutide

  • Ashsc...
  • May 12, 2021

Rybelsus (semaglutide) "My endocrinologist prescribed this to help with PCOS. I weighed 211lb and started on 3mg and lost 6 lbs while walking for 2 miles a day most days for a month. I was bumped up to 7mg, but insurance wouldn't cover it and I ended up gaining the weight back after trying Victoza and Byetta. My insurance changed and my endocrinologist started me back on it at 7mg since I already had Byetta in my system. During this time, I found out I have Ehlers-Danlos and was recommended to start weight lifting to help strengthen my muscles and lost 13 lbs in a little over a month which I'm sure exercise has helped contribute. My menstrual cycle has been regular and on time for the first time in 4 years. I haven't had any major side effects other than a little nausea when I first take it in the morning and diarrhea, but I had that issue beforehand. I know a lot of people have said the side effects are terrible, but it hasn't been for me and you should certainly give it a try. It's honestly been wonderful."

10 / 10
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  • Daddy...
  • Taken for 6 months to 1 year
  • October 13, 2019

Ozempic (semaglutide) "This Ozempic was prescribed as a last ditch effort to get my A1C down prior to starting insulin. The first .25 dose caused significant nausea but I battled through it for a couple weeks before starting the .50 dose. The nausea increased with the higher dose and I considered stopping but had lost ten pounds and had zero appetite and my sugar was down so chose to continue. It's been about 6 months now, I'm taking the full 1.0 dose and although the nausea is still an issue it has lessened in severity and comes in "waves" so I know it will pass and just tough it through. I've dropped about 30 lbs and counting, my A1C is now in the prediabetic range and I've been able to lower doses of other medications that were causing significant side effects. I now feel better, look better, have more energy and no longer have the constant food cravings or desire to overeat. If you can ride out the nausea the benefits of ozempic are huge, for me anyway."

8 / 10
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  • CSC
  • Taken for 6 months to 1 year
  • November 9, 2020

Ozempic (semaglutide) "The first few weeks I suffered some nausea and my food intake was reduced probably about 30% as a result. I started at .25 for a month then .50 for a month then 1.00 which was full dose. I have been on the drug for about 6 months now. My weight dropped 30 pounds from 264 pounds to 234 pounds and I seem to be levelling at that range. My target BMI weight for 6 foot 3 is 210 but I would be happy at 225. I have found that Ozempic did cause some constipation but overall once I achieved the full dose for a few weeks I felt much better. The weight loss has really helped how I feel and I will Be doing my 6 month blood work up next week. Hoping to see some good results with glucose which was at 6.0 and cholesterol at 259. Overall I am very happy with the results to date."

8 / 10
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Frequently asked questions

  • Randy
  • Taken for less than 1 month
  • September 21, 2020

Ozempic (semaglutide) "Been taking Ozempic for two weeks now. I wondered how this drug could allow some - or most - people to lose weight. Now I know - it makes you feel sort of sick to your stomach, and takes away your appetite - at least that is my result so far. I am hoping to develop a tolerance to it. Not a real pleasant experience so far, but I have not vomited or had diarrhea as some users have reported. It does appear to be lowering my blood glucose somewhat, which is the primary reason I am taking it. I am also taking metformin but have been able to reduce the dosage. Still only taking .25 mg of Ozempic so result of higher dosages is unknown now. Will post again in a month or two with higher dosage usage results."

6 / 10
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  • Lorelei
  • Taken for 1 to 6 months
  • March 13, 2020

Ozempic (semaglutide) "I've been on Ozempic for 2.5 months now (10 weeks as of today) off label for PCOS. I started with a dose of .25 for the first four weeks, and have been on .5 for the remaining six. On the .25 dose, I felt my appetite was slightly reduced and I had some mild nausea. As soon as I went to .5, the side effects started and I started getting extreme nausea, diarrhea, rancid burps, and I can no longer eat. If I eat more than a regular ham and cheese sandwich in a day, I feel extremely nauseous and the burps come back. As of my last doctor's appointment I've lost about 3 pounds, but I don't know if I can keep this up. I'm miserable. I won't know until next month whether it's working like my doctor has intended because she needs blood tests to verify all of that, so I can't speak to how effective it has been yet."

5 / 10
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Are you taking this medicine?

  • New...
  • Taken for 1 to 6 months
  • August 21, 2020

Ozempic (semaglutide) "I was moved to Ozempic from Januvia. At the time I started Ozempic, I'd brought my blood sugar down to what would translate to an A1C of 5.5 or so, and I'd managed to kick most of the insulin I was on. I started Ozempic at 0.25 units per week and had mild nausea and diarrhea, but my appetite vanished and I could barely bring myself to eat. Once I started the full dose, my blood sugars began to climb rapidly. I'd be fine in the mornings at first and then experience wild spikes between meals, until finally my fasting sugar started to climb out of my desired range. I actually had to take MORE insulin, not less, just to keep my fasting BG below 7. Ozempic was absolutely NOT worth it - even with the lower price here in Canada, the cost is ridiculous, the benefits never materialized and the effects on my appetite destroyed the healthy diet I was trying to eat. Good example of how new isn't always good."

1 / 10
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  • OZano
  • Taken for 1 to 6 months
  • November 14, 2019

Ozempic (semaglutide) "I have been on Ozempic semaglutide for 7 weeks and am presently on .50mg dose. Positives - I have lost 15 pounds, my A1c has dropped from 6.8 to 6.0. I feel great. Negatives - Blood level dropped fast with the first shot, after that no issues, slight nausea right after the shot. It doesn't last more than 30 mins. Positives outweigh the negatives IMO"

10 / 10
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More FAQ

  • Alicat
  • Taken for less than 1 month
  • August 16, 2020

Rybelsus (semaglutide) "I have been exercising, dieting, counting every calorie and weighing food and meal prepping. No weight loss and fasting blood sugar still over 160 after 24 hour fasting. Tried metformin, got diarrhea but no weight loss, no decrease in appetite. I need to lose 30 lbs and have lost 8 by skipping breakfast having lunch a d skipping dinner some days. If I eat before 5pm I don't get reflux and I sleep better. I am having night sweats but I'm 56 so menopausal. I'm not taking hormones. I increased the dose to 7 mg had diarrhea for 3 days, I'm up now to 14mg on an empty stomach. No more diarrhea, and I have energy. I am 142 now and trying to eat healthy but mostly eating no more than the size of my fist and staying as active as I can, I'm feeling cravings go away."

10 / 10
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  • owlet
  • Taken for 6 months to 1 year
  • April 26, 2021

Rybelsus (semaglutide) "I've been on Rybelsus for eight months, and I have lost about 34 lbs. I started on the 3mg dosage, and after two months, moved up to 7mg, where I have stayed. However, one of the major side effects is slowed gastric emptying, which can lead to extreme stomach pain if you make the mistake of eating too much in a day. After a couple of bad episodes, I had an endoscopy, just to be sure nothing else was wrong - but ultimately, my gastroenterologist said that it's just the effect of the Rybelsus."

8 / 10
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  • George
  • Taken for 1 to 6 months
  • December 14, 2023

Rybelsus (semaglutide) "I'm 75, 180 lbs. I was diagnosed with T2D 10 years ago. My A1C was 9.2. I was put on Metformin 2000mg, A1C went down to 6.2 and since then I was swinging between 6.2 and 7.2. I eat lots of carbs and my physical activity is a one-hour walk three times a week. I feel hungry most of the day. My endocrinologist recommended Rybelsus, the family doctor said I shouldn't do it. I decided to go and see what happens. First month: 3mg plus Metformin 2000mg. No change in diet and exercise, lots of carbs. Minor nausea, A1C went down from 6.8 to 5.7, lost 10 lbs., morning sugar down from 135 mg/dl to 105, 2-hour sugar after meals down from 250 to 140. Second month: 7mg pills split in half. Terrible constipation for the first week. Stopped taking pills for 3 days, constipation persists with a lesser extent. Switched back to 3mg. Minor nausea, after a week, constipation almost gone. Weight no longer goes down. A1C went up to 5.9. To be continued..."

8 / 10
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  • L0v3Lf3
  • Taken for less than 1 month
  • March 14, 2020

Rybelsus (semaglutide) "Second day on Rybelsus 3mg. Was too afraid to try it, but glad I did. No side effects at all except the loss of appetite. I will return and provide an update. I need to lose 60lbs. Have tried Victoza & Invokana and got very sick within the first couple days of taking them so I hope Rybelsus is the answer for me. I exercise and watch my diet, but my glucose levels were still too high."

10 / 10
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  • BonBon
  • Taken for 1 to 6 months
  • July 13, 2021

Ozempic (semaglutide) "Started Ozempic about 7 weeks ago. Dosage .25. First week noticed some nausea, a lot of gas, some reflux and diarrhea. Each week side effects were getting worse. Nausea very bad, pains in left side, waves of heat, no energy an all In all just feeling BAD! Diarrhea is bad and a bit uncontrollable. Have not raised dosage due to being afraid of worse side effects. Have lost 5 pounds. Appetite is definitely less. My sugar numbers have not improved that much, which leads me to believe it is what I am eating. I still crave sweets. I have some jittery feelings at times! I am very discouraged."

3 / 10
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  • Sunny
  • Taken for less than 1 month
  • March 8, 2020

Ozempic (semaglutide) "I started Ozempic on Friday. I'm hoping the side effects go away because it has helped my BS readings and helped with cravings. The side effects I'm having is horrible diarrhea, joint and muscle pain and fatigue. I don't know how long these symptoms will last but hopefully not long."

10 / 10
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  • Irish...
  • Taken for 6 months to 1 year
  • October 12, 2019

Ozempic (semaglutide) "I started Ozempic in March 2019. This allowed me to quit taking actose and Glipizide. I weighed 287 lbs. and my A1C was 7.8 and rising. I was a little nauseous for the first week and then it subsided I’ve not experienced any since. Now in October I weighed in at 231 and my A1C is down to 6.2. My energy is up and I feel great. This medicine definitely improved my quality of life. I’ve never gone beyond the .5 dosage and my endocrinologist said that an increase is not necessary for me. I would recommend everyone give it a chance, I know it won’t be for everyone but if it works your daily life will change for the better."

10 / 10
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  • AuntK
  • Taken for less than 1 month
  • March 2, 2023

Ozempic (semaglutide) "I can barely eat or even drink water. Sure, my blood sugars are low, but I can't even eat 300 calories a day on this, it's like chemically induced anorexia. Extreme weight loss thru starvation is not something I consider a treatment. Extreme Nausea is after even every sip of water. It took me 3 hrs to eat 1/2 c of plain oatmeal today - one of the few things that doesn't make it worse. I need a therapy that is life sustaining, and includes healthy diet. Under 300 calories a day is not healthy."

1 / 10
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  • aggies
  • June 7, 2021

Ozempic (semaglutide) "I started taking this 3 weeks ago. I didn’t really have any terrible side effects other than fatigue, but after my third injection, nausea, diarrhea and stomach pain hit me with a vengeance. I feel like I ate rotten eggs. I’m not sure I want to continue taking this. I might try injecting it in my thigh like some others have tried. I hope it works because my glucose readings have been in the 90s to 120."

7 / 10
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  • SSH
  • Taken for 1 to 6 months
  • February 25, 2020

Rybelsus (semaglutide) "I have been on Rybelsus for 2 months, I started on the 3mg and did fine, no side effects and actually felt more awake and focused. Then I went to the 7 mg and was very nauseous and vomited almost nightly. Felt like my food never digested. I apparently am pretty sensitive to this medication and since my blood glucose and A1C have been good I am taking this every other day which has lessened the nausea and discomfort. I have lost 6 lbs in the past month and that has been great cause I needed that. So we will see how this continues but I feel pretty good."

9 / 10
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  • Ctano
  • Taken for 1 to 6 months
  • December 8, 2019

Ozempic (semaglutide) "I was on ozempic .5 for 6 months, during that time I had severe stomach cramps, diarrhea. My blood pressure went out of control causing my vision to double, I have 6th cranial nerve palsy caused by spike in blood pressure, EKG now shows I have a right bundle branch blockage, may need a pacemaker. I never had anything like this before, I have had the same dr for 15 years, and he is also concerned. I believe the Ozempic is the root cause, my eyesight may not get completely normal. Will be getting legal advice"

1 / 10
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  • MICK
  • Taken for 1 to 6 months
  • November 5, 2020

Ozempic (semaglutide) "A1C was 6.2 with Metformin. Went on Ozempic for 3 months. I had side effects of bad nausea, vomiting, and watery diarrhea. Lost 27 lbs. Couldn't eat 4/7 days. My A1C now 5.6 and it is not worth it for me."

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  • GEORGE...
  • Taken for 1 to 6 months
  • September 23, 2020

Ozempic (semaglutide) "Ozempic is a nasty drug to take. I have been on the toilet 8 - 10 times per day even on just a low .25 mg dosage. It does however lower my blood glucose better than anything else I have taken in the past."

6 / 10
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  • Bird...
  • Taken for 1 to 6 months
  • August 12, 2020

Rybelsus (semaglutide) "Bad news: I started taking the 3mg Rybelsus for 30 days did well. Have been taking the 7 mg for the past 3 weeks and I have had diarrhea, stomach bloating, nausea, and can barely eat anything or drink. Even the smell of food makes me sick. I am extremely exhausted and hate feeling like this. Calling doctor tomorrow. Good news: dropped a1c from 8.4 to 7.3 in 6 weeks and lost 10 pounds, and also cut back in my 24 hr insulin and fast acting due to not eating. —is it really worth it though???"

3 / 10
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  • Mario
  • Taken for 1 to 6 months
  • July 14, 2021

Ozempic (semaglutide) "Started taking Ozempic back in February after I asked my doctor to put me on it because of reading a British study on weight loss by semaglutide. Started at the .25 mg level for three weeks. Went to .50 for another four weeks and have been on 1 mg thereafter. No serious side effects apart from some belching, acid reflux after bedtime and rare diarrhea. Significant loss of appetite, change of taste in foods, change of perceived texture of foods, significant reduction in alcohol enjoyment and intake, and increased sensitivity to cold. My A1C has gone from 6.7 to 6.0, and I have lost over 35 pounds since the start. My cholesterol is down to 115 and LDL down to 50, something I have never seen before. Overall, the results far outweigh the downsides of this drug and it has provided the most positive results faster than any other medication I have tried before."

10 / 10
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  • Baker...
  • Taken for 1 to 6 months
  • May 24, 2019

Ozempic (semaglutide) "I have been on Ozempic for 3 months now and I find this drug works like none I have tried before. The first 6 weeks were rough, burping, headaches, fatigue, nausea, but I stuck it out. I’m so glad I did. My A1C has gone from 8 to 6.8 in three months. I have lost 20 pounds, gone from 180-160lbs. And my sugars on the daily have seen a vast improvement. The major thing I have noticed is after being on the drug for this long that recovery time after eating a high carb or high sugar food is back to normal. Appetite is still lacking but it’s mostly an aversion to ‘bad’ food. I can no longer sit and eat an entire burger, it’s just way to much, but a healthy salad, I can eat the whole thing! I have seen major benefits from this drug. I have way more energy, and no more 3pm crash. Tips while adjusting to the drugs: tums, gravol, lots of sleep, light healthy meals, and remember to drink water! Also I found injecting Ozempic in the hip lessened the symptoms for the first while."

10 / 10
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  • Ozempic
  • Taken for 1 to 2 years
  • September 27, 2021

Ozempic (semaglutide) "I have lost 60 lbs in a year and a half on the diabetic dosage of 1 mg. I started on .25mg in January 2020 for 4 weeks, went to .5mg thru June, then 1 mg. Other than having to reduce back to .5 mg for 4 weeks in October 2020 due to some increased nausea, I remained on 1 mg weekly dose. Yes there was some nausea, but Ozempic actually worked on appetite control and reduced cravings for large amounts of desserts, pasta, and other foods. This was accomplished even without much change in activity or food choice, strictly in food volume. Despite losing a few lbs with other GLP 1 drugs in the past, Ozempic "clicked" for me: 214 down to 153."

10 / 10
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  • JJano
  • Taken for 1 to 6 months
  • April 29, 2021

Rybelsus (semaglutide) "This is the first medicine I've used that has actually helped me lost weight. I take a bunch of psych meds that have packed on pounds (Seroquel). I started with the 3mg titrating package and had slight heartburn for a few days. By the end of a month on 3mg I lost ~6lbs. I had slight nausea at first on the 7mg dose (after a month on 3mg) but that faded. Now, after a month on 7mg, I'm down a total of 14lbs total (233 to 219). Before this med I've been trending only upward for the past 4 or 5yrs. I'm super stoked that I might be able to see under 200lb again in a few more months."

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.