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Entresto for Heart Failure User Reviews (Page 3)

Entresto has an average rating of 5.0 out of 10 from a total of 179 reviews for the treatment of Heart Failure. 40% of reviewers reported a positive experience, while 49% reported a negative experience.

Reviews for Entresto

  • Davetx
  • Taken for less than 1 month
  • November 10, 2018

"I’m a 56 yr old male. I had a heart attack and felt great after a stent placed. First visit with dr a week later he prescribed entestro. Within a month I was in the ER with total kidney failure. Am now on dialysis and in need of a kidney transplant. Kidney function is less than 20%. My kidney function was normal the week before starting this drug."

1 / 10
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69 Report
  • 682 g...
  • Taken for 6 months to 1 year
  • February 13, 2022

"Permanently light headed , kidney pain , cough , constantly itchy , drowsy , unable to sleep , fatigue and mental confusion. Had a 'wake up ' moment and refused to take any more and instantly started feeling mental sharpness returning. Has been the worst experience of heart failure medication I've had in 15 years. Was hopeful in the beginning my ejection fraction of 30 would see improvement...it is now 18! Will score 1/10 , only as I can't give lower!"

1 / 10
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  • macsek
  • Taken for 1 to 6 months
  • January 10, 2016

"A short time after having started on Ernesto 50 mg I' noticed a reduction in my vision. Eye surgeons weren't quite sure what it was except that they saw an inflammation on my sight nerve. They guessed at temporal arthritis and put me on cortisone. But even now, several months later I feel a faint flare-up of the same feeling on my sight nerve. Could this be connected to the blurred vision as listed as one of the most important side effects, you think?"

6 / 10
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Frequently asked questions

  • Bud
  • Taken for 1 to 6 months
  • June 9, 2019

"My husband has been taking Entresto for 3 months, this past week we have seen a big improvement in him. His E.F. is 14. His feet and legs are not swelled, his breathing is better and he’s not so tired all the time. He was diagnosed with CHF Oct/2018, had quadruple bypass in Dec/2018. This is the best we have seen him in a long time!!"

9 / 10
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  • Dplusm
  • Taken for 1 to 6 months
  • August 25, 2019

"47yrold female. Chf at 46. DT-LVAD last year. My meds are changed often as they are still working on perfect balance and types of drugs I respond best to. I was put on Entresto about two months ago. Significant improvement in daily functions and energy level. Feel stronger and more awake. It's like running on caffeine. No other side effects."

10 / 10
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57 Report

Are you taking this medicine?

  • Randy...
  • Taken for 2 to 5 years
  • September 21, 2022

"To clarify for those who misunderstood the ejection fraction (EF), it is the percentage of blood in your heart that is ejected. If it ejected 100%, you would be in serious trouble! Thus the 50%-70% “normal” range. Following near-fatal heart failure and surgery, in 2009, I spent a week in an induced coma. My EF was below 30%, and 6 months later, at 30%, they implanted a defibrillator and Pacemaker. Approximately 2018, the cardiac team took me off Coversyl 2mg and put me on Entresto 24+26 x 2 per day, total dose 48+52. My energy and ability to function shot up immediately, allowing me to do more of what I enjoy. Gradually, over 3-4 years, I have lost muscle strength and joint motility. It finally occurred to me that Entresto could be responsible for this deterioration. I called the cardiac team to tell them I am stopping the Entresto. They tried to blame my B3 for the muscle problems. I found this site and have read every review. For me, Entresto was good for 6-12 months."

5 / 10
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  • Mike
  • Taken for 1 to 6 months
  • October 25, 2019

"I have an EF of 11, and been on entresto for about 3 months. No side effects to speak about, but on my last scan a week ago, there's no change to my EF Don't be put off by negative comments, if you are offered it try it."

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More FAQ

  • James
  • Taken for 1 to 6 months
  • March 25, 2019

"Cardiologist started me on Entresto 6 months ago for my heart failure. No follow up/blood work done till recently which came as a result of seeing my regular doctor who was concerned about edema on left side. My doc told me blood work should be done within two weeks of starting this drug. Kidney function was normal before starting this drug, now Stage 3 kidney failure in six months on entresto. Cardiologist dropped the ball and I intend to sue. My life expectancy has dropped by over ten years."

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  • 48inTx
  • March 24, 2017

"I am 48 years old and I have Left bundle branch block (LBBB) and a low ejection fraction 30 to 35.. I used to be on Lisinopril and Carvedilol before taking Entresto and the Lisinopril didn't suit me well and gave me anxiety.. I have been on Entresto and Carvedilol for almost a year and I enjoy taking the medicines together.. I workout 3 times a week and I am losing weight and my ejection fraction is increasing.. I am not having any side effects but a very light dizziness if I sit for a long time and get up fast.. I can feel that my heart works easier than before and my average blood pressure is 117/68 Entresto is about $485 a month; however; if you go online and register they provide a discount card and after my insurance I pay $60 a month "

10 / 10
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  • MacyM...
  • January 19, 2017

"This drug is expensive. Patients on Medicare D, can soon find themselves in the donut hole, thus causing added problems for many. (not if money is no object) . There is not enough information out on this drug's ability to prolong life.Doctor mentions very few side effects. Main ones were, Low BP, angioedema, high potassium/kidney damage. I bring up more side effects, he does not agree...yet Drugs.com list side effects that I am having with this med. Back pain/side pain. I have had difficulty walking due to these pains and resort to a walker. Heart Failure caused by poor stent placement in LAD. )-: My EF is sliding downwards from 40-45% to recent echo of 30-35%. I thought this med was the answer to HF. Needing more solid info."

4 / 10
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  • crap...
  • Taken for 1 to 6 months
  • January 24, 2019

"My doctor as well as Cleveland Clinic recommended Entresto. To make this short, every side effect listed for this med I ended up having. After gaining 20 pounds in 30 days, I called it quits on this poison as dizziness turned into vertigo, nausea kept me on the couch leaving me feel lifeless. Prior to this med I was slowly losing weight via diet and lifestyle changes and dropped from 247 to 217 in four months. I was feeling better and on my way to recovery--NATURALLY! After a week of stopping this med I gained another 5 pounds, as expecting quick results is like turning the Titanic. The sudden weight gain is like picking up and carrying three 1 gallon bottles of milk and carrying them with me all day long. I have never felt so near death and so pray that I come out of this spiral before this iceberg called Entresto takes me down. If Russian roulette is your game, then Entresto is the name."

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58 Report
  • Macca
  • April 7, 2020

"Male 61 years old I had a tissue aortic valve inserted late 2017 thanks grandma for the hand me down, then in early 2019 I started to get fatigued and short of breath it was not good. September 2019 my cardo re fitted my PC with a defib and put me 1-1/2 tablets a day 24/26mg have never felt better since taking entresto seriously I feel like a new man again it is just good to move freely climbing stairs hills etc etc without becoming tired and fatigued ."

10 / 10
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  • Dave...
  • Taken for 6 months to 1 year
  • May 4, 2020

"Have afib and a 22% EF after exercise went up to 35-40%. Weight gain from 308lb to now over 360lb and eating less and low sodium, constant joint pain blurred vision and depressed because i can't wear any of my clothes. After late April in the donut hole with my insurance and monthly medicine bill on entresto and eliquis jumps from 47.00-147.00 a month till almost December. I asked my doctor to put me on carvedilol or something else that does the same thing only dirt cheap. I am now reducing my dosage to one a day instead of two and getting off it. I read these reviews and i would say 10% of people its good for the rest it sucks!"

3 / 10
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  • Amber
  • Taken for 1 to 6 months
  • July 19, 2021

"I think the success rate and ability to tolerate the medication may vary from patient to patient. However, I think it can be a game-changer for many living with CHF and is worth a go. My husband (age 39) was diagnosed with CHF in April 2021 with a LVEF of 14%. He started carvedilol, Farixga, spironolactone, torosemide, and Entresto. It took him a week or so to adapt to the medicine, we even went back to the ER a couple days after his release because he felt terrible and was vomiting. They adjusted his diuretics and he started feeling much better. We went back today (3.5 months later) for another Echo and EKG and his LVEF has improved from 14% to 40%. He's not on the maximum dose of Entresto yet. We are hoping in 3-6 more months his LVEF will be at a normal range above 50%. He is a golf instructor and works in the sun all day for up to 10 hours and usually takes over 20K steps a day. He is living a completely normal life now (minus all the meds) with zero symptoms."

10 / 10
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  • Anonyy
  • August 23, 2020

"My husband was put on Entresto by a doctor who was “is supposed to be the best”. I hate this stuff! His entire personality changes when he is on it. Tired, moody, sleepy and unhappy. He fluctuates from high to low dose. I can always tell when he takes higher dose by his mood. He has been taking it for four years and stubbornly won’t try something different because the doctor PUSHES this drug. They obviously get some sort of kickback!"

3 / 10
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  • mazda
  • Taken for 1 to 6 months
  • December 12, 2016

"I felt dizzy, light headed, confused, and my throat felt like it was closing .I can't tell if it is any good because you are on so many medications when you have stage 3 heart failure. But I do know this the trials should have went forward to look at all evidence these fast tract FDA approvals have killed a lot of people because of serious side affects look at the law commercials you see everyday ."

3 / 10
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  • Bren
  • Taken for less than 1 month
  • March 13, 2022

"My husband died with sudden cardiac arrest, three days after starting Entresto. He had bundle branch block on the left side for years. His other medicines kept him stable and working. Three days....only three days of this drug! BEWARE! Has anyone looked into a lawsuit against this company???!"

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  • Mark
  • Taken for 6 months to 1 year
  • January 9, 2022

"My team did not know how Entresto worked they knew I might get GERD and that I might get low potassium. They did prescribe me potassium and I got weaker. The last two times I had to go to there office in a wheelchair had trouble breathing so they added Isosorbide. At no time did they think high does Entresto was a problem, but when I was in there I was not able to breathe well or walk . I realized when symptoms started it was the Entresto. I refused the drug next drug time I was able to walk 18 hours later but it took 110 days to have no more Entresto caused side effect symptoms"

1 / 10
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  • Ginger
  • Taken for 1 to 2 years
  • February 4, 2019

"I was diagnosed with Congestive Heart Failure on 2017. My EF was 8%. I was told I was going to die. I meant a group of Doctors at UCLA. A great Dr. recommended Entresto. I have had several side effects from medication joint pain every day and weight gain 40 pounds. It's a struggle but I am alive and my EF is approving ."

9 / 10
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  • drobe...
  • Taken for 6 months to 1 year
  • November 11, 2022

"I was diagnosed with EF of 40% 8 months ago, and have Cardiomyopathy. I started on Entresto 50mg twice a day. Had many side effects for a month or two whilst my body adjusted to the medicine. But after that only sometimes have back pain. Now 8 months on I just had another Echo. 62% EF (heart function). My cardiologist is very happy for me. He said I will be on Entresto for the rest of my life. I will say that since day 1 of being on this drug I stopped alcohol consumption. I also eat better foods and do exercise twice a day. Fast walk in the mornings around 2km and at night 1km. Dr said no hard core running or anything like this with my condition and on this drug. Overall I think my brain function has improved as well. I highly rate Entresto as a 'wonder drug' and so does my cardiologist."

10 / 10
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  • Newtown...
  • Taken for 6 months to 1 year
  • May 9, 2022

"I began taking Entresto at the recommendation of a cardiologist after I went in for a routine exam and echo. My echo was an EF of 25. I began taking Entresto and realized an improvement in my echo. Problem was my Blood pressure, which normally was in the 140/95 range dropped to 90/60. I became extremely hypotensive everyday, nauseous, shortly after taking my morning dose and then fainted twice within 8 weeks, falling to the floor. I met with other doctors and they told me to get off Entresto. Since now I take no Entresto I have a regular blood pressure and no fainting or hypotensive feeling or episodes."

1 / 10
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  • TraceP
  • Taken for less than 1 month
  • September 19, 2019

"Can't give the best review as I have only been on it about a week but noticed that I am not nearly as tired. Hoping this is because of the entresto.. Was previously on ramipril, carvedilol, and furosemide. Currently EF is 20% so hoping this helps long term."

8 / 10
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  • Toffe...
  • July 23, 2017

"After 3 weeks on this trial drug, Entresto I started having breathing problems. Was out of breath going up stairs and short of breath most of the time. By my 4th month I had gone from being a 51 yr old to seeming like an 81 yr old. I had no energy and a 10 min walk home now took over half hour. Even though I was walking as slow as possible I had many stops to catch my breath and get my heart rate down. I can no longer walk anywhere and rely on a lift. Stopped taking drug. Maybe down to feeling like a 71 yr old now. Just hoping the side affects will completely disappear. Meeting with consultant end of week."

1 / 10
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  • Die...
  • Taken for less than 1 month
  • March 17, 2019

"I have had CHF for 4 years and still try to body build and my EF has been 10 to 15 and no higher. This drug better work I was diagnosed at 39 I'm on spirolactone and lasix. Also and if I gain weight that will be fine but only ten pounds I need to gain I been in and out of hospital over 50 times and I'm in stage four heart failure that's why I continue to hit the gym and work full time even though it's hard so I will keep u updated just started three days ago."

5 / 10
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  • Mommaof
  • Taken for 1 to 6 months
  • August 12, 2018

"I’ve only been on Entresto for 3 months, and after reading a lot of negative reviews, I was very leery about this medication. However, after adjusting to the med (it does take time, it will make you tired, it did make me feel like I lost my spark), I started to feel increasingly better. My fatigue lessened and my energy increased. I started to feel more normal, for the first time since being diagnosed with left ventricular noncompaction cardiomyopathy (LVNC) 2 years ago. My EF (ejection fraction) went from 12% to 32%, and I’ve only been on it a few months! I cannot express how thankful I am for Entresto! I know it’s not for everyone, but I have tolerated it so well. Every weekly blood draw has been great, and most importantly, I continue to feel a little better each week. As a mother of 5 children ranging from age 2 to 13, I’ll take all the energy I can get!"

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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