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Pantoprazole for GERD User Reviews (Page 4)

Brand names: Protonix, Protonix IV

Pantoprazole has an average rating of 4.7 out of 10 from a total of 249 reviews for the treatment of GERD. 33% of reviewers reported a positive experience, while 51% reported a negative experience.

Reviews for Pantoprazole

  • Paul
  • June 6, 2019

"Starting having real bad GERD . Went on Nexium one morning and one at bed time. Eating only applesauce and toast in the morning and chicken and rice for diner. Lost 30 LBS. Still having bad GERD. Went to my Doc and he put me on Pantoprazole. On the second day of taking this drug started to have stomach pain. Waiting for a return call from my Doc."

1 / 10
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29 Report
  • Anonymous
  • Taken for less than 1 month
  • November 20, 2016

"I have been on 40 mg twice a day for 2 weeks. I can't shake this awful headache. Then a week ago I woke up feeling as though I was hit with the flu. Body hurting all over, severe headche, restless, no energy, cotton mouth to the extreme, no appetite. Been so sick haven't even noticed if the medicine is actually working for what I am taking it for. Went to the doctor tested me for flu, pneumonia, strep, u name it and found nothing. Pain is unbelieveable and continous. Stopped taking the medicine yesterday and showing huge signs of improvement. I will stick to my bottle of tums a day over that horrific pain. Not worth it. Hurt burn is pain full but at least I can go about my day with it. This medicine I couldnt even get out of bed"

2 / 10
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39 Report
  • Wagriff
  • Taken for less than 1 month
  • October 6, 2016

Protonix (pantoprazole) "I have had severe Gerd/Acid Reflux for nearly 6 years. It has put me in the hospital 7 times now and has totally destroyed my teeth which I have always been meticulous about caring for. Presently, it's also causing me swallowing problems and voice troubles. The pain the Gerd can generate is an actual true "10"-Far far worse than the pain I experienced from a Quad Cardiac Bypass surgery. My doctor gave me Protonix for it and it worked Very well on reducing, perhaps, 80% of the pain. Unfortunately, the medication caused Peripheral Edema Big time and I had to go off of it again. The edema immediately went away, but the pain came back too. I have noticed this reaction from almost all proton pumps that I have tried to date."

5 / 10
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Frequently asked questions

  • Sissy
  • Taken for 10 years or more
  • April 23, 2020

"I've been on this medication for a few years. It did great until now. I have burning and itchy vaginal and anus. Dark urine, gurgling down through the intestines. And I'm having swelling in my legs with chills. Some stomach pains as well. I stopped the medicine to clear up which it is now doing. I had bleeding in the vaginal and anus area too. I will be getting a colonoscopy this summer."

5 / 10
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24 Report
  • Jeannie...
  • Taken for 1 to 6 months
  • June 18, 2023

"I take this for GERD but it doesn't work. I am experiencing headaches, and brain fog, and can’t eat. I have no energy. I don’t walk anymore for exercise, I simply cannot continue it. I was prescribed .40 mg twice daily. I just can’t do this. Is it just me that reacts this way to the medication?"

3 / 10
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8 Report

Are you taking this medicine?

  • Clalu...
  • Taken for less than 1 month
  • April 1, 2017

"I've had moderate to severe GERD for 10+ years; last med I was on was Lansoprolzale for 5+ years. Recently, I was switched to Pantaprozale Sodium 40 mg a day; have taken it for less than a week and it's been hell since the first day I took it. Have had sweats and the worst joint and muscle pains and cramps, and ulcers in my mouth along with a sore throat. At the NP's advice who prescribed it I also take Magnesium. I'm stopping this med today and hope these side effects go away soon."

3 / 10
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  • Diana...
  • February 1, 2021

Protonix (pantoprazole) "I have had GERD for over 10 years now and I tried nexium otc helped but I ended up in the hospital because I had chest pain really bad. The hospital put me on cafarate and protonix it helped right away I take protonix twice a day and cafarate before every meal and at bedtime. I can eat anything I want and have no more pain in my chest. I will continue to take this medication as long as I can because I can eat anything without any pain"

10 / 10
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20 Report
  • Nay
  • Taken for 5 to 10 years
  • April 6, 2016

"I have been taking this medication for 6 years now religiously every morning. I am now concerned of the long term risks. They are linking this drug and other PPI's to a higher risk of devoloping dimensia. I take 40 mg. every morning and my doctor has prescribed me 20mg. So I can start to slowly lower myself off from taking so much. I have not started the 20 mg. yet since I've been on 40 mg. for years im afraid of how my body will react to it. Overall this medicine works better then any other medicine I have tried for my acid reflux. I don't think I will be able to live without it."

9 / 10
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  • Lew
  • Taken for less than 1 month
  • April 18, 2019

"Prescribed pantoprazole by specialist twice a day. Started with massive headache then terrible nausea. Throat burns! Can't even eat mild foods without pain. Seems counter-productive. Even water is hard to swallow. This drug is not good for me. Only been on for a week and a half. Every day is worse even though I'm eating considerably less (and bland) due to discomfort. Foods I could eat 2 weeks ago cause me pain now. I tried to stick it out for at least a couple weeks, but this is the worst. I need to go back to doctor to see if something else is going on."

1 / 10
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  • MacMo...
  • March 7, 2009

Protonix (pantoprazole) "I love protonix. Only wish it was more affordable. My insurance company will only cover the generic form--which is NOT the same. I found the name of the manufacturer but again the insurance company won't cover it. The three months I was on the generic all my symptons returned. Back on the protonix for two weeks and everything was gone!"

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  • Anony...
  • Taken for less than 1 month
  • July 18, 2018

"20mg worked really well with heartburn/reflux symptoms, but unfortunately this gave me terrible bloating, constipation and horrific smelling wind (literally had to open windows and put a fan on to air out ONE small room, and even then it still stank and lingered - talk about embarrassing and unpleasant). Not to mention I looked like a combination of 6 months pregnant/ a fat overstuffed sausage around my lower stomach which was very distressing and made me even more self conscious - (I'm a very petite woman and it was so bad it was showing through even my loosest t-shirts) like the awful wind wasn't enough! Perhaps it will work for you but I cannot say I'd recommend as it was awful. As soon as I stopped the digestive issues began to ease off , literally 24+ hours after the last dose I was already getting relief from the constipation & bloating. It's a no from me."

3 / 10
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29 Report
  • Anonymous
  • Taken for less than 1 month
  • March 28, 2018

Protonix (pantoprazole) "I took Protonix for about a week and every time I took it, I got a severe headache every day. It did help to keep my heartburn at bay but to me, it is not worth it for the side effects. My mood dropped because of this medicine and I just did not feel like myself. I have stopped taking this medicine and I am now taking Zantac 150mg. Took effect and it is working wonders for me."

1 / 10
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30 Report
  • Piceno
  • Taken for less than 1 month
  • December 23, 2016

"If you have diabetes type 2, I strongly urge you not to take this drug. Even though they say that increase of blood sugar is rare, this happened to me. About five days I started taking this drug (40mg), I started to feel lightheaded. My morning reading of blood sugar is normally about 6.6 three hours after breakfast, but I started getting readings of 11.6. I felt like hell. Even worse, the spike in blood sugar caused my blood pressure (controlled by medication) to also spike to about 165/80. I decided to stop the Pantoprazole. The lightheadness went away, and my blood pressure returned to normal. Be very careful with this drug. There are a couple of websites which warn of increase in blood sugar."

2 / 10
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34 Report
  • Bad...
  • December 1, 2011

Protonix (pantoprazole) "I only discovered I had GERD from an endoscopy. I've always had a horrible stomach, but recently had a constant sore throat. The Protonix worked wonders! But then I noticed I was constipated and had a huge appetite. I briefly switched medicines but went back to Protonix. It was when I started taking it again and had two abdominal exams that I realized my liver was enlarged. The doctors immediately dismissed it since I've had my gallbladder removed. They said it was scar tissue. My daughter has eosinophilic colitis so I'm really just focused on her gastrointestinal care, but at my next follow up I will address the issue. I did cut out milk/dairy from my diet and that seemed to help as much as the medicine!"

7 / 10
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49 Report
  • MaryMac
  • October 29, 2008

Protonix (pantoprazole) "I loved this drug--until my insurance company said it was the 'same' as another less expensive drug. I've been miserable ever since. The acid reflux is returning, I am bloated and bowels are always a surprise. My surgeon is thinking a second surgery might be needed - if only I could afford the Protonix it could be avoided."

10 / 10
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57 Report
  • Jenny
  • Taken for 10 years or more
  • September 17, 2019

"I have been taking pantoprazole 40 mg for 15 years for acid reflux and it has worked well. Three months ago I got a yeast infection in my esophagus with severe burning and esophagitis. Took 200mg of Difulcan for 3 weeks which cleared it up. Now 3 months later it is back with a vengeance. I have a-fib and am afraid of side effects of anti-fungal. Anyone with this experience? Did anything help?"

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  • Jenny
  • Taken for 1 to 6 months
  • August 20, 2020

"I love this medicine pantoprazole other than the fact that it has given me insomnia. I have absolutely no acid reflux like I did with Nexium, I just cannot sleep at night now. I would love to be able to fall asleep at a normal time rather than when the sun is coming up."

9 / 10
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19 Report
  • ikp
  • Taken for less than 1 month
  • February 3, 2024

"I only took one pill after diarrhea and GERD kicked in high gear. It worked like a charm. Don't need any more, but was grateful of having them from previous ER visit 1 year before. Just take one and try to eat better; it's really the best way. No alcohol too."

10 / 10
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  • Hll
  • Taken for less than 1 month
  • November 11, 2021

Protonix (pantoprazole) "I started taking protonix a few months ago. I’m 19 and have never had any prior health issues besides bad acid reflux. I was taking protonix for about a week and started to notice awful headaches. By week two I was having awful dizzy spells and I avoided going to class because I thought I was going to pass out. I thought all of these side effects was related to when I had COVID a month prior so I overlooked it. After taking this medicine for a month I went to the ER twice because I felt like my heart was skipping beats, I was nauseous, couldn’t catch my breath, tingling in my hands and feet, and my dizzy spells were unbearable. The doctors summed it up to panic attacks which I knew was wrong because I’m not an anxious person. I researched protonix online and realized a lot of other people had the same side effects. DO NOT take this medicine!!! It made me feel like I was going crazy and for a whole month I couldn’t do anything because of dizzy spells!"

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • November 12, 2018

"Instead of fixing my acidity it increased and now my stomach is more sensitive that it has ever been. I can't eat almost anything. I have acidity on basic foods like pear, boiled vegetables and bread. So yeah, don't recommend to anyone."

1 / 10
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  • rickw...
  • February 2, 2010

Protonix (pantoprazole) "My gall bladder was acting up and the pain was terrible. I took a Protonix as soon as I got out of the doctors office (with a sandwich and doctor pepper) about 15 seconds later I was burping like CRAZY. Viola!! The pain subsided considerably in less than 3 minutes. AN hour later it was like I never even had the pain! I felt MUCH, MUCH better."

9 / 10
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50 Report
  • Faith
  • Taken for 10 years or more
  • August 20, 2019

"I had my gallbladder out years ago, so long ago this medicine wasn't generic and very expensive. It was the only thing that relieved my pain. Since I've tried so many times to get off this medicine but I experience heaviness in my chest an lots of pain. Trouble breathing. My body is now so depending on this I'm stuck. I pray no one gets dependent on this or any other medicine with all these side effects."

8 / 10
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21 Report
  • Tester
  • July 2, 2008

Protonix (pantoprazole) "I have a Lap Band. Before I had the band I had no problem with heartburn, then after I got a couple adjustments, I had acid reflux and heartburn so bad I was eating like 20 Tums a day. Zantac no longer works, or anything for that matter, so I went to my doctor and he gave me samples of Protonix. Within minutes my heartburn was gone. I have slept through the night without vomiting my own stomach acid. Highly recommend this drug. If you have a Lap band then you know how horrible it can be."

10 / 10
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  • lvb
  • Taken for less than 1 month
  • February 19, 2020

"I have taken it for mild reflux (which was discovered through gastroscopy, but produced no specific symptoms, however could be linked to throat problems and bloating). I've stopped it taking after 4 weeks, because occasional stomach pains appeared and some old skin problems flared up. After another month my reflux was becoming stronger than ever, with clear symptoms."

2 / 10
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  • Good-...
  • November 11, 2013

"I have been on Omeprazole / Pepcid for 5 years and pantaprazole for couple months in the middle, if the symptoms became worse. I used to feel little itchy + seon my hands 5 years ago when I took pantaprazole for a month. My doc had me to switch to Omeprazole regularly. After an year my doc had me to switch to Pepcid regularly since Omeprazole gave me acid rebound! So it became like, if the symproms show up bad, I would start with Pantaprazole coupld weeks and switch to Omeprazole and finally switch to Pepcid ongoing. But since an year ao. Pepcid + Omeprazole do not work! My doc had me to take Pantaprazole for the past 6 months regularly. Its perfect, its working very well for me. No more sleepless nights! Surprisingly no itching this time!"

8 / 10
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37 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.