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Pantoprazole for GERD User Reviews (Page 2)

Brand names: Protonix, Protonix IV

Pantoprazole has an average rating of 4.7 out of 10 from a total of 249 reviews for the treatment of GERD. 33% of reviewers reported a positive experience, while 51% reported a negative experience.

Reviews for Pantoprazole

  • Recov...
  • Taken for 6 months to 1 year
  • August 11, 2021

"25 year old male, no other medications. I started this medication in February of 2021 for gastritis while my doctor figured out what was really wrong. I have never had a panic attack or suffered from anxiety/depression before. Approximately a month after taking this medication I began having several panic attacks a day and freaking out over several things that I normally would never think twice about. After 2-3 more month on this med the anxiety morphed into depression, and intrusive thoughts. I had several other side effects that developed such as weakness, and ringing in my ears. After months of trial and error on testing, we finally figured out that my gallbladder was working at 19% and had it removed in June 2021. I talked with my doctor about these meds and how I suspected that it may have been causing all of my issues. My doctor agreed due to PPI causing B-12 and magnesium deficiency. Currently weening off and hope to be done soon. I’ve already started feeling better in recent weeks."

1 / 10
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  • rv Rob
  • April 16, 2013

Protonix (pantoprazole) "I have taken it for about 7 years now. I never had stomach problems but got what they thought was an ulcer. Later endoscopy showed no ulcer, but signs of Barrett's esophagus. I also had hoarse voice, especially in the morning. pH study pointed to GERD. Long story short, no more hoarseness. Subsequent scopes show no signs of esophagus damage. Now for the bad. Very rarely, when I eat fast, I do get choking sensations that I did not ever have before. Also, if I run out of the medicine and/or miss a dose or two, wicked bad heartburn. Never had heartburn before. As long as I stay on it, I am good."

7 / 10
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  • ANDY
  • Taken for less than 1 month
  • March 25, 2020

"I've been prescribed 40mg of protonix twice a day for severe acid reflux. Ever since starting on this medicine it's been a nightmare I have side effects of severe migraine in the back of my head to my neck and upper back, and joint pain. I'm 31 year old male and never had experienced anything like this in my life. The pain is unbearable. I just called to see what they can do for me.. waiting for a response.. But I'm defiantly not taking these anymore. I don't take any other medication so I'm almost certain it's the medication."

1 / 10
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Frequently asked questions

  • borde...
  • Taken for 2 to 5 years
  • November 14, 2015

Protonix (pantoprazole) "Unfortunately I have suffered with very serious GERD for 28 years and it has been awful. I have tried every prescription medicine out there and none of them work for me like Protonix does. I feel very close to a normal human being on this medication but none of the others lived up to Protonix. I received a horrible notice from our health insurance provider this past week and after December 31, 2015 they will no longer cover this drug. Their only suggestion for me with severe reflux is to try something else!!! I have tried EVERYTHING else on the market and nothing works but Protonix. NOTHING! I am so sick with the GERD when I am off this medicine I am pretty much house bound because I am so sick. For me it is a miracle drug!"

10 / 10
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  • Anu
  • October 2, 2020

"Took this stuff for 4 months on my GIs advice. I absolutely felt pathetic while I was on it ( stomach cramps, constipation, dizziness, headaches and more). Finally the day arrived when GI said stop doing it (cold turkey), oh boy! It made my life miserable from that day. My b12 went super low (close to 100), I developed gastritis and my GI wanted me to do Prilosec now. What an idiot! Started Pepcid now to manage the acid rebound from my initial dosage of 4 months. Never ever going back on this rubbish again."

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Are you taking this medicine?

  • MsS
  • Taken for 1 to 6 months
  • May 17, 2020

Protonix (pantoprazole) "I took this for about 2 and a half months. Half way through I told my Dr it wasn't working. He said I was under stress. Not. Then I developed a hot, itchy rash on my arms and face. They told me to stop taking it and start Nexium. I didn't because to me they seem to have the same risk. Being off Protonix is almost as bad as being on it. Terrible acid reflux. I am sleeping sitting up, I can't eat very much, I can hardly wake up and start falling asleep around 7 PM and I have had a headache off and on for 3 days. Going to an Internal Medicine Specialist next because I’d like to know the reason for the reflux I have had for 1.5 years not just take a medication."

2 / 10
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  • Tee
  • December 17, 2015

Protonix (pantoprazole) "This was the worst medication I have ever taken. I was just prescribed this medication last week. After on it for only 2 days I stopped. Headache was unbearable. I thought I was gonna have to go to the hospital to get a cat scan until I realized it was probably the protonix. Then there was the nausea they came along as well. Five days later, I'm still nauseous, but used ginger to help with that. Overall, I will never use this medicine again."

1 / 10
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  • MDano
  • Taken for less than 1 month
  • June 20, 2019

"Got prescribed this pantoprazole a month after getting treated for H Pylori. Did nothing at all to control the acid and was still taking Tums to stop the pain. A week after I started taking the drug, I had extreme nausea lasting a day and a half. I felt dizzy and weak. Couldn't eat anything apart from plain crackers and could only stomach water. Nausea only eased when I stopped taking the drug. Be wary of taking this drug, I wish I never took it at all."

1 / 10
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  • Terry...
  • February 22, 2016

Protonix (pantoprazole) "I had heartburn and a history of an ulcer so my doctor put me on Protonix and when taking it daily I feel great, however with the new information about this kind of drug being linked to dementia and also that is can cause one to be addicted to it and cause rebound acid I decided to stop it. I am on day 4 and now a mild constant burning is in my stomach and often back up to my chest. I was given them for heartburn but the doctor wrote gerd and later I developed gerd on days I tried not to take it so I am concerned about this all coming back by 10 times worse. I am looking into a natural alternative first as dementia is all around in my family and my new holistic/medical doctor says this type of drug is dangerous."

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  • Reflu...
  • Taken for 2 to 5 years
  • December 29, 2019

"I have taken 40mg Pantoprazole for about five years for reflux. Went to doc because I was hoarse for a long period of time. Doc said it was acid reflux. I thought, NO WAY, because I’ve had acid reflux before after eating pepperoni or something, which was just horrible. Went to gastro doc and he confirmed acid reflux and put me on Pantoprazole, 2 per day. I quickly stopped taking the morning one because I just didn’t need it. After about five years the pharmacy filled my script with Pantoprazole manufactured by Kremers Lannett (white pill) instead of the normal manufacturer, Teva USA ( yellow pill). Within a couple weeks I was having to sleep sitting up and acid was still bubbling up. Horrible!!! Took wife’s yellow pills and it immediately cleared up. Weird!!"

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  • whyte...
  • March 31, 2012

Protonix (pantoprazole) "Worked at first to bring heartburn/acid reflux under control, however I had to stop taking it because it started causing severe stomach & abdominal pain. Now control through diet & Tums EX. The pain from the Protonix side effect was terrible when it started happening."

1 / 10
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  • Sp00ns
  • Taken for 1 to 6 months
  • January 2, 2021

"I’ve had acid reflux for awhile now, alongside POTS, women’s health issues, blood clots, severe anxiety/depression, and more. Needless to say, I’m a complicated case. However, I asked my doctor for something to control the incessant heartburns, pain, and GI issues it’s caused. After Pepcid failed me, she prescribed Pantoprazole. It helped my symptoms within 24 hours. I could eat anything I wanted, and I wouldn’t have heartburn or anything. However, I noticed over the course of 2 months on this, my anxiety has increased so much that it’s causing more frequent panic attacks, or makes me feel all day/night like I’m going to have one only for it to never go away, and makes me feel unable to break out of the anxiety. Definitely recommend if you’re having GERD issues, but if you have any anxiety/depression, be prepared that while you get the upside with treating the GERD, the additional anxiety can be the downside of taking this."

5 / 10
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  • Boot
  • Taken for 2 to 5 years
  • October 26, 2019

"I was put on Pantoprazole about three years ago after having trouble swallowing food. I went to see my kidney doctor today, he told me he found out that taking it was bad on my kidney and not take it any longer, so I threw them in the trash"

5 / 10
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  • Bob
  • Taken for less than 1 month
  • January 20, 2021

Protonix (pantoprazole) "My stomach really started hurting on Dec 23rd. I’ve battled reflux many times over the years. I’m 57 but not like this. I started on Pantoprazole on Monday this morning my stomach is starting to feel bit normal. I hope so as I’ve had this gnawing nausea although has gotten slightly better at times since 23rd. even few occasions like I never had it but didn’t last long. I have slight other symptoms as you all know heartburn indigestion slight feeling through but it’s the stomach that worries me anyone have any thoughts about stomach nausea I’d love to hear. And does it take the meds time to fully kick in. Thank u to everyone nothing short of GODS blessings always."

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  • Jim
  • Taken for 5 to 10 years
  • March 27, 2013

Protonix (pantoprazole) "Started taking this about 8 years ago after developing an ulcer from taking Aleve. Was fine for a few years, with only flatulance and loose bowel movements. For the last 3 years, I started developing asthma symptoms (phlegm in throat and lungs, coughing). Stopping Protonix cleared it up. Took 1 pill again and the asthma started again. Too bad, I really liked this medication."

5 / 10
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  • Cheryl...
  • Taken for less than 1 month
  • October 15, 2021

"Doctor prescribed these to me 7 days ago for GERD. After the 3rd day I had to go off of them . Every bone in my body hurt. I had heart palpitations late at night even after taking my dose in the morning, I am already prone to anxiety, and this made my anxiety 100x worse. I would wake up in the middle of the night unable to go back to sleep. I could feel my heart rate elevated. Then the headaches came. I also had random crying spells that were not brought on by anything happening. I had to go off of them. The side effects immediately stopped the day I went off of them. These pills are horrible. I asked my doctor to take me off of them due to the side effects and she didn't even believe me. She said "well you have anxiety so thats all that is. It is not the pills". It absolutely IS the pills!"

1 / 10
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  • Bobby
  • Taken for 1 to 6 months
  • March 1, 2018

Protonix (pantoprazole) "I would wake up coughing up fluids and constantly have acid reflux symptoms, which began to lead to swallowing issues and high anxiety. My doctor put me on pantoprazol (protonix) and I take it once every morning. 40mg. I am not someone who likes medicine and won't even take tylenol for a headache. I love my pantoprazol (protonix) and hope it continue to keep my issues away."

10 / 10
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  • Atari
  • Taken for 1 to 6 months
  • June 4, 2019

"I was put on this drug for GERD & gastritis, I wasn’t scoped then I was just scoped year later. I have acid reflux worse since starting this med it gives me severe anxiety I’m bloated 24:7 and constipated brutal. My bowels reek foul. I have migraines and sore chest back and abdomen gurgles. Try getting off but I get acid rebound so bad you have no choice. I’ve been in bed for 3 months. I’m exhausted from side effects. I wouldn’t take this drug ever again I can’t even walk barely nausea bloating 8/10 24/7."

3 / 10
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  • Carri...
  • March 7, 2014

"Pantoprazole helped with the acid reflux. My problem started four years into taking it. For months I experienced flu like symptoms, such as muscle and joint aches, diarrhea, weakness and extreme fatigue. After MANY tests were done, I was told that I was vitamin D deficient. I know that any meds that control stomach acid also block the absorption of vitamins and things your body needs. I stopped taking Pantoprazole and was put on prescription vitamin D. After just one week, I felt like a new person. I cut out foods that bother my stomach and cut my portions in half. I may have to chew a Tums once in a while, but I feel great. So watch how long your doctor has you on this drug. It took four years to have the side effects that I had."

7 / 10
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  • looking...
  • September 17, 2011

Protonix (pantoprazole) "If you don't get ahead of an attack, this pill won't work. I have been on it for years now and have had little problem with it until it didn't work one weekend so I doubled up on it and ended up in the hospital a week later with seizure due to hypomagnesia (or however you say lack of magnesium). Make sure you are getting all your electrolytes when taking proton pump inhibitors."

8 / 10
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  • Anonymous
  • Taken for less than 1 month
  • November 16, 2019

"I had been taking OTC Zantac twice daily for GERD. During a medical appointment with PCP, I was prescribed Pantoprazole because my abdomen was tender on palpating. My visit had nothing to do with heart burn, rather for an elevated BP and heart palpitations. I took the Pantoprazole for about 10 days. During that time, my abdomen became horribly bloated. I looked like a pregnant woman with an old face. The sense of pressure and fullness was miserable and made it difficult to discern cardiac symptoms from the discomfort of stomach bloating. It also caused my heart to race even more, despite being placed on a BP medication. That’s when I remembered having been prescribed Pantoprazole last year and stopping it due to racing heart. I also experienced loss of appetite and a constant bitter taste in my mouth. It did eliminate GERD, but was not worth the side effects, especially those affecting a vital organ like the heart. I will refuse future instructions to take this drug."

4 / 10
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  • Clavo
  • Taken for less than 1 month
  • September 22, 2020

"I have used Prilosec for over 10 years, without any issue, however, my Doctor felt that Pantoprazole would be safer for me. Well not at all, after taking 1 pill a day for a 5 day period, I came down with severe abdominal pain, to the point that I could not roll out of my bed, the pain then move to my left shoulder, the the right, then my neck, then my hips. All of these within a 3 week period. I have been prescribed a muscles relaxer, I think that it has helps, but I still have the neck cramps and hip bone pains. be very careful with Pantoprazole."

1 / 10
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  • Dlighty
  • Taken for 1 to 2 years
  • October 17, 2019

"I was taking Pantropazole for around 2 years. My primary dr. said to get off it as she don't like me on it long term. After about a month of being off it my stomach aches stopped. I no longer have bowel problems, the drowsiness stopped and I feel better . I haven't had any GERD issues yet either."

2 / 10
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  • Jett
  • Taken for 2 to 5 years
  • May 30, 2018

Protonix (pantoprazole) "Since my early twenties (I am mid 50s now) I have had great difficulty swallowing with a feeling that something was stuck in my throat, followed by esophageal spasms, followed by projectile vomiting of stomach acid. Episodes could last for up to 10 hours. I've been hospitalized several times while have sever episodes of uncontrollable spasms/vomiting for hours. I was misdiagnosed for decades, had my throat stretched by laparoscopy/balloons periodically and tried a variety of medications. Nothing helped. I was extremely underweight from not being able to eat for so many years. Finally, a doctor put me on Protonix and it was a miracle. Unbelievably life changing. My only complaint was I gained 20 lbs in the first year I was on it. I take it twice a day and can eat whatever I like with no reaction."

10 / 10
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  • Anonymous
  • April 15, 2009

Protonix (pantoprazole) "I had the worst side effects with Protonix. I took it for 15 days and experienced increased anxiety and heart palpitations. I also had dizziness, nausea and insomnia. Going off of it took 6 days to feel somewhat normal."

1 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.