Skip to main content

Zyprexa for Depression User Reviews

Zyprexa has an average rating of 5.1 out of 10 from a total of 78 reviews for the treatment of Depression. 37% of reviewers reported a positive experience, while 44% reported a negative experience.

Zyprexa rating summary

5.1/10 average rating

78 ratings from 84 user reviews.

Compare all 183 medications used in the treatment of Depression.

10
15%
9
10%
8
12%
7
8%
6
9%
5
1%
4
1%
3
0%
2
6%
1
37%

Reviews for Zyprexa

  • Emero
  • Taken for 1 to 6 months
  • March 13, 2020

"I was put on 17.5mg of Zyprexa in 2017. I took this for 6 months before I finally decided to listen to my body and stop listening to the so-called experts. Zyprexa made me dull, depressed, and robotic. I now lack empathy, emotion, concentration, and I no longer get pleasure from things I used to enjoy. Zyprexa zaps the joy from your life, basically. There is no upside. Please, please avoid this drug. It will steal your personality, and nobody will believe you except for the people who have also been victims of this drug."

1 / 10
Was this helpful?YesNo
451 Report
  • Trapped
  • Taken for 2 to 5 years
  • August 15, 2019

"Zyprexa made me dull and gain weight, then found it's impossible to stop taking. Even with a very, very slow taper, I have terrible withdrawal symptoms that I never ever experienced before olanzapine. I only took 1.25mg, and after 3 years of tapering I'm down to about 0.7mg. Now I have heart arrhythmia, akathisia, insomnia, I feel dazed and out of it, erectile issues, and don't feel pleasure or get excited about anything. Olanzapine has ruined my life. If I could do one thing differently in my life it would be to never ever start taking this horrific drug."

1 / 10
Was this helpful?YesNo
247 Report
  • tried...
  • Taken for 6 months to 1 year
  • January 10, 2014

"Would give this a 10. Have tried every anxiety/depression, SSRIs and MAOIs, etc. out there. One day on this and I felt wonderful, like I woke up as a new normal person. Yes you may gain a lot of weight but only if you eat carbs. You just cannot take this and eat chips, candy, etc. Lean meats, proteins and veg and you will have NO problems, the effect is worth it. If you can put the fork down, it can change your life. My Dr. warned me about the potential for weight gain, but told me he thought I had the willpower to resist the cravings to eat junk, which I did. Try it."

10 / 10
Was this helpful?YesNo
374 Report
  • TheGo...
  • March 22, 2015

"I am in shock as to the MIRACLE of Olanzapine. A 2-year severe depression, with extreme anxiety, insomnia, and paranoia DISAPPEARED the first week on this medicine. Before, my depression was so bad; I stopped brushing my hair, I could barely function, my sadness was so profound. After 1 week on Zyprexa, I am finally back to myself, taking good care of myself, sadness is 90% gone, smiling again!"

9 / 10
Was this helpful?YesNo
322 Report
  • serj
  • Taken for 2 to 5 years
  • December 18, 2019

"This drug is awful. I should've stopped from day 1. Now I'm in the 4th year and just started tapering because I'm one of the good boys that always listen to his parents and doctors. Please don't be a fool. Don't take this drug; it will make you lose years of your precious life. Better be drug-free as you know the only winner of your supposed condition is the big pharma that only wants your money every month."

1 / 10
Was this helpful?YesNo
151 Report

Are you taking this medicine?

  • Vani
  • Taken for less than 1 month
  • June 13, 2019

"Stay away! I took 15 mg Zyprexa for 2 weeks, and I feel so tired. My vision is blurry, weak hand-eye coordination, and it's difficult to speak or understand anything. Why is this drug still being prescribed?"

1 / 10
Was this helpful?YesNo
152 Report
  • maddie
  • April 19, 2019

"Put on this drug for anxiety, loss of weight, not sleeping, all connected with something that happened to me. On it for a month at 10 mg and had pounding blood pressure in ears, sudden headaches, ankles swelled up 2x their size, gained 25 lbs. in a month, huge appetite, foggy thinking, flat personality, and dizzy. After I got off, I felt much better. Off it now for 2.5 months, and I can't lose any weight, and in fact am still gaining, so can't get it out of my system. How can I get it out of my system? I don't want to become diabetic or get heart disease, but this drug can do that and I'm not even on it! Doctors are putting people on it that should not be given this drug; it should be a last resort if at all. This drug can cause permanent changes chemically, in metabolism, and dopamine receptors in the brain. Is there no antidote?"

2 / 10
Was this helpful?YesNo
146 Report
  • Gigi
  • Taken for 1 to 6 months
  • April 13, 2020

"This medication Zyprexa is a miracle worker ! I was in a very deep depression, suicide thoughts. I started feeling better after just a few weeks.I have been on it 6 weeks now and its keeps getting better. The Doctor is now increase it to 10mg, I feel more tired, but that will lessen as time goes by. I feel like me again !!!"

10 / 10
Was this helpful?YesNo
124 Report
  • jpurp...
  • Taken for less than 1 month
  • May 8, 2016

"Started taking 2.5 mg Zyprexa a day 3 days ago. For years have taken 60 mg Celexa, 0.5 mg Clonazepam, and 0.5 mg Xanax if I need for an emergency panic attack. They worked well until 6 years ago; my husband died. A year later, my dad died. Two years after my dad passed, his wife died. Then, 4 months later, my son, who had Down Syndrome, died on the operating table. I was really going into a deep black hole by then, but it just got worse. A friend of 25 years died of cancer not even a year after my son. I can really feel a difference in just 3 days. No crying so far; been outside and to the store without panic attacks. Sleep really well. So far, eating hasn't been a problem; have lots of energy, and just feel better. Hoping for a new lease on life!"

10 / 10
Was this helpful?YesNo
202 Report
  • Josh
  • Taken for 1 to 2 years
  • October 29, 2019

"I've been on Zyprexa for about a year and a half at 15mg. I was put on Zyprexa to help with severe treatment resistant depression. I also take 150mg of Effexor and 300mg of Welbutrin. In the past year my depression has slowly gotten worse and I suspect it's the Zyprexa. About 3 months ago I decided to taper myself off Zyprexa. I went from 15mg to 7.5mg for 3 months. I experience moderate sleeping issues (I sleep between 4-8 hours and wake up about 10 times during the night), nausea and a dramatic increase in depression. My highs are lower and my downs are longer and more severe. My two questions are this: 1) Has anyone experienced increased depression as a result of taking Zyprexa 2) Has anyone experienced an increase in depression as a result of Zyprexa withdrawal. "

6 / 10
Was this helpful?YesNo
110 Report
  • Anonymous
  • Taken for 1 to 6 months
  • March 27, 2019

"Zyprexa made me feel very tired and irritable. I almost cussed my boyfriend over a small convenience, My eyesight kept blurring up, always hungry, and then I started getting this uncomfortable drowsy feeling that lasted the whole day. STAY AWAY from this garbage."

1 / 10
Was this helpful?YesNo
112 Report
  • Ed Mc...
  • Taken for 5 to 10 years
  • September 15, 2017

"Zyprexa withdrawal is the worst thing that has ever happened to me in my 55-year-old life. I took 2.5 mg for 6 years. Sure, it helped me sleep for a few months, and that is why I did not know what was causing the terrible grief and overall health problems I was experiencing. I was fainting without warning because of this drug. It ruined my life, and I have not touched Zyprexa in almost 2 years! It is a drug so terrible it should not be prescribed to anybody. The makers of this drug should be totally ashamed of themselves. They really should be punished for what they have done and continue doing to people's lives with this drug. No joke."

1 / 10
Was this helpful?YesNo
128 Report
  • kestrel
  • Taken for 2 to 5 years
  • May 25, 2013

"I started taking Zyprexa over two years ago for intrusive thoughts I was having as a result of obsessive-compulsive disorder/depression. While the Zyprexa helped remove intrusive thinking, it added about thirty pounds onto my slender frame, made me severely tired, and took away my sex drive. In addition to these adverse effects, I was unmotivated/uninterested in many activities that used to give me pleasure. I had a 'so what' attitude about life in general. All because of this medicine. What really frightened me about taking this was my cholesterol went sky-high, and my blood sugar was also very high, making me an at-risk candidate for diabetes. I am finally off of this."

2 / 10
Was this helpful?YesNo
183 Report
  • lovem...
  • December 13, 2014

"Had a few psychotic episodes a few years ago, was hospitalized and was put on Zyprexa and a few other meds. I was diagnosed with BPD (borderline personality disorder), major depression, and fibromyalgia. I felt hungry all the time and gained 70 lbs. My dose was 20mg a day plus I was on other meds. Finally, I was weaned off all other meds as the months went by. I cannot say my hunger and weight gain were completely due to Zyprexa, but I do know that I now take only 5mg a day at night, sleep well, my hunger is normal, and I have lost weight with good healthy choices and exercise. I no longer have depression, and life has never been better. Zyprexa, therapy, exercise, support, and nutrition have saved my life."

7 / 10
Was this helpful?YesNo
149 Report
  • audhep
  • Taken for 1 to 6 months
  • February 16, 2021

"After reading the reviews, I was hesitant to start Zyprexa, but I was at rock bottom with my central nervous system. Let me tell you, 2.5mg has saved my life. I have CRPS and severe anxiety. It calms down the mind, calms the severe anxiety, and makes me sleep at night. I’ve had no side effects from this med. it really is a life saver. Don’t be afraid to start this medicine if you really need it."

10 / 10
Was this helpful?YesNo
64 Report
  • Onzin
  • Taken for less than 1 month
  • March 23, 2021

"So, one doctor recommended me to take this pill without no reason why. The effects of this drug were: -insomnia -bruises on my neck -weight gain -desire for sugars -anger and low estimation of situations Giving drugs for schizophrenia for just depressive People? Think about it twice."

1 / 10
Was this helpful?YesNo
56 Report
  • Missy
  • Taken for 6 months to 1 year
  • May 5, 2020

"I've been on zyprexa for 9 months now, zyprexa has done wonders for me. No more spontaneous deep dark days ahead of me, my close family can really see a difference, I'm just worried about long term effects of this drug. I have bipolar 1 with psychosis."

8 / 10
Was this helpful?YesNo
67 Report
  • wildc...
  • May 3, 2016

"Started up Zyprexa 5mg along with 80mg of Prozac and 200 mg of lamctiI don't remember the last time I have felt this good.My family feels like they are living with a different person.I feel like a different person.My does of Prozac was upped and the lamctiI the same day they added Zyprexa.I feel wonderful but gaining weight.Even if my stomach feels full and bloated I sometimes still want to eat.Afraid to stop the Zyprexa because my life was a living hell for me and everybody in it.I never want to go back there.I could not survive such a deep dark depression again.I used to believe all the good years were gone and I was just existing.But I am living and loving it!!!!But extremely worried about the weight gain.Already have type 2 diabetes."

10 / 10
Was this helpful?YesNo
100 Report
  • Meano
  • Taken for 1 to 6 months
  • October 31, 2018

"A doctor said I had bipolar and put me on Zyprexa and Lexapro. It was a nightmare, I told my doctor it made my depression worse and that I developed restless leg syndrome while on it. The doctor completely ignored me. After months of this horrible nightmare, I switched doctor's and was told I am NOT bipolar, but suffer from depression. I was tapered off Zyprexa and now I feel 100% better. Thankful"

1 / 10
Was this helpful?YesNo
67 Report
  • Anonymous
  • January 16, 2011

"I took Klonopin and Paxil for 15 years to treat my anxiety disorder. I had to detox from the Klonopin this past spring. I got off the Klonopin and switched my Paxil to Lexapro (sex side effect issue). I am also a recovering alcoholic. My doctor did not want me on Benzo's anymore (says it increased alcohol cravings). I stayed on Lexapro only for 9 months, but my anxiety came back strong on just the Lexapro alone. I almost resorted to taking Xanax before I switched doctors. My new doc gave Zyprexa a chance. I am on my 7th day and I haven't felt this 'normal' in 5 years. I take 5mgs at night and it has ended the 'chatter' in my head, and removed my anxiety. Great medicine so far."

10 / 10
Was this helpful?YesNo
127 Report
  • rb1979
  • Taken for 1 to 6 months
  • April 9, 2016

"Was on Zyprexa from Mar 2015 till Aug 2015. At first it seemed like it was mellowing me out a bit, and I could sleep through the whole night, which was an improvement. After a few months I noticed my depression was getting much worse. Came off the drug cold turkey, and went through one of the most serious withdrawals one could face. Depression, severe anxiety, PTSD, night terrors took over. To this day Apr 2016, I have still not returned to the way I was before I started taking this horrible drug. Depression and anxiety are still bad, not as bad as 6 mos ago, but still worse than when I first started taking it. I'm convinced this drug can cause permanent brain damage."

2 / 10
Was this helpful?YesNo
87 Report
  • jogra...
  • November 2, 2011

"I have taken Zyprexa 2.5 with Zoloft for years and couldn't function without this combination. It was prescribed because the Zoloft just didn't take care of the insomnia and mood swings. Zyprexa 2.5 has been a God-send."

10 / 10
Was this helpful?YesNo
116 Report
  • Lilone
  • Taken for 1 to 6 months
  • September 30, 2018

"I have ever been a fan of antidepressants as I feel they are a bandaid for underlying problems. I starting to think differently. My doctor put me on 2.5 mg along with 0.5 Xanax. After years of feeling depressed and hopeless I now have more energy, sleep well at night waking up feeling great. I have also have gained weight which I needed to do. I give Zyprexa a 10 stars"

8 / 10
Was this helpful?YesNo
62 Report
  • Renay
  • October 22, 2013

"I have been on this medicine for about 3 weeks now. I wake up hungry, drenched in sweat, and have also gained 15 pounds. Im thinking about getting off this medication. I have also had crying spells, irritability, and mood swings, then some other days I have felt fine. Its weird. I'm going to give it a few more weeks, and if nothing improves as far as my moods i will get off of it."

Was this helpful?YesNo
95 Report
  • Anonymous
  • February 13, 2012

"This medication is a great sedative, if that's what you're looking for. It's not euphoric, it just makes you sleepy. But it caused me to gain over 40 pounds in less than 2 months. I now get depressed just looking in the mirror. My doctor says it just makes you hungry, not gain weight, but the amount of weight I gained in such a short time is unnatural!"

7 / 10
Was this helpful?YesNo
99 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.