Skip to main content

Nefazodone User Reviews & Ratings (Page 2)

Nefazodone has an average rating of 9.3 out of 10 from a total of 161 reviews on Drugs.com. 93% of reviewers reported a positive experience, while 5% reported a negative experience.

Reviews for Nefazodone

  • Answe...
  • Taken for 2 to 5 years
  • September 8, 2021

For Depression "I come to this review page to see if anyone has found a medication similar, at least kind of worked as well as nefazodone. My story is a little different. I haven't been on in for 20+ years, in fact, I’m in my late 20s. I had been on every drug on the market. Living everyday with SI, then I started nefazodone and for the first time I felt like living was possible. I was on it for 3 years and I felt like I was living life like how I imagined it was supposed to be. Then the medication was gone. Ripped out from beneath me. This drug saved my life, and shame on TEVA for not valuing human life. I don’t feel as if I have much time left on this earth, but I beg you all, urge everyone to keep fighting for the medication that showed us, and gave us life again."

10 / 10
Was this helpful?YesNo
24 Report
  • natur...
  • March 19, 2011

Serzone (nefazodone) for Depression "I was on Serzone for 6 years and it gave me my life back. It truly is a miracle medicine and should not get the bad rap. I never had any liver problems, in fact I only had dry mouth as a side-effect. It did not affect my libido or ability like the Cymbalta that I am on now. I had liver problems with Depakote ER and I don't understand why it does not get the negative press. Serzone is amazing and I am going to work with my new psychiatrist to be back on it once again. I can't wait to get my life back once again!"

10 / 10
Was this helpful?YesNo
77 Report
  • Aime_...
  • August 2, 2017

For Anxiety "This drug changed my whole life. Suffering from anxiety depression, it did not feel or look like depression; nevertheless it was. Mostly this expressed in anxiety, especially new events or chores, not to mention jobs or large changes. Within 4 weeks, the Psychiatrist asked me if it was helping; I wasn't sure, but, within 8, I told him, "I feel like...me!" That was 20 YEARS ago. It still works and, no, that is not an illusion. I have tried to gently go off several times under doctor's care, and always return to my unsettled state of fear. I have had a successful career and personal life, am healthy and content. Nefazodone save me."

Was this helpful?YesNo
47 Report
  • harpi...
  • March 26, 2011

Serzone (nefazodone) for Anxiety "I have been using Serzone and the generic versions for over 15 years now. When the brand was pulled from the market, I tried Wellbutron, Celexa and Prozac. All three had horrible side effects and I finally found a doctor who would prescribe me the generic of Serzone again. This medication keeps me on an even keel, keeps the anxious thoughts from overwhelming me and helps me sleep at night. My liver panels are always perfect and my only side effect is that I have to take it right before I go to bed as it makes me sleepy."

9 / 10
Was this helpful?YesNo
75 Report
  • Beatles...
  • Taken for 10 years or more
  • July 11, 2021

For Anxiety "I was on Nefazodone for 26 years after trying several other antidepressants that had side effects. It had no side effects and made me feel like myself again. Now that it been unavailable for almost a year I have had to go off of it while starting Trazodone. I have been off of Nefazodone for a month and on Trazodone for 2 months. I am anxious, depressed, scared and cry everyday. I am hoping the Trazodone will start working since it is the closest thing to Nefazodone. I have been going up in 25 mg increments since starting it. I don't want to have to try something else. I am outraged at Teva. Apparently they don't care about us. I believe that Nefazodone is or was used by so few people that it wasn't worth their while to make it. Back in April I tried calling, writing Teva and the FDA and got nowhere. I am praying it will be made again, but I don't know how difficult it would be to transition back."

10 / 10
Was this helpful?YesNo
24 Report

Are you taking this medicine?

  • valley
  • Taken for 10 years or more
  • February 23, 2019

Serzone (nefazodone) for Depression "I went on Elavil to try to help severe migraine. While it was somewhat helpful for the headaches, it immediately began making me gain weight. I put on 40 pounds, and it was a shock because I had never been overweight before. I was 42. I changed doctors, and she put me on Serzone. Within a week I dropped 4 pounds! I was so excited, I began walking again and trying to lose weight. Overall, I lost the 40 pounds and kept it off. Then Serzone was banned, and I had to change antidepressants. The weight piled on, and in six months I gained 60 pounds on Cymbalta. Now, I’m in my late 60s and my new doctor refuses to let me try Nefazodone , which is now available again. I’m so angry. I’ve dropped that doc and am going to a new psychiatrist next week. Here’s hoping she is more brave and understanding and will let me switch to Nefazodone. I hope I can still lose weight even though I’m 25 years older. Being overweight makes me more depressed than any of my life’s problems."

10 / 10
Was this helpful?YesNo
36 Report
  • Its_b...
  • Taken for 10 years or more
  • January 9, 2022

For Anxiety "As of 12/20/21 nefazodone is out of shortage and again available. I was finally able to fill my prescription on 12/27/21. This medication has been so helpful for me. I tried many others and this seems to be the only one that along with controlling the depression also keeps my anxiety in check. I have been on this for over 20 years."

10 / 10
Was this helpful?YesNo
20 Report
  • MzEarle
  • Taken for 10 years or more
  • January 27, 2021

For Panic Disorder "I was prescribed this medication approx 20 years ago after being homebound for 6 years with agoraphobia. 17 years ago when I was became pregnant, they attempted to change my medication and it was all bad. I had horrible effects from it. I was placed back on my Nefazodone and I as back to normal in no time. I just learned today after wondering why my script still wasn’t filled that it is no longer available. Teva you have to put this medication back on the market. My anxiety is at 1000 just knowing what I’m going to go through without it. I’ve get labs done every 6 months and have never had any liver issues at all. Please help us patients that have been saved by your medication."

10 / 10
Was this helpful?YesNo
25 Report
  • tina
  • Taken for 10 years or more
  • January 12, 2021

For Depression "Tried 7 different medications before going on this one. Been on it for 20 years. I don't suffer anymore and this medicine has been a Godsend. I hope it comes back soon. I realize there is a drug shortage on this medicine so I cut it in half so as to save as much as I can. My anxiety, depression and bad mood came back like a monster like it did 20 years ago. Please Teva, hurry and bring this back so the ones like me don't run out."

10 / 10
Was this helpful?YesNo
25 Report
  • nav
  • Taken for less than 1 month
  • January 17, 2024

For Anxiety "I’ve suffered from severe GAD and treatment-resistant depression. Before trying nefazodone, I’ve tried many different classes of antidepressants such as SSRIs, SNRIs, MAOIs, and other medications. None of them worked to calm my anxiety, which interfered in my life in an extremely negative way by preventing me from socializing, causing panic attacks, making me get in fight or flight mode over the smallest things, and causing me to isolate myself from the world. Also, before nefazodone, my depression was unbearable. There was no joy or pleasure in things. I did not look forward to anything, and life felt hopeless. One day, I was looking up medicines to treat severe GAD and treatment-resistant depression, and nefazodone came up. After reading up on it, I decided to ask my psychiatrist if I could give it a try, and he said yes. It has been 27 days since I started taking nefazodone, and one thing I can say with confidence is that it works. Anxiety, panic, and depression have drastically decreased."

10 / 10
Was this helpful?YesNo
5 Report
  • Hope
  • May 27, 2009

Serzone (nefazodone) for Depression "I have taken this antidepressant for as long as it has been on the market. It was and remains the only antidepressant that works for me. It has almost zero side effects when compared to the Tri-cyclics, SSRIs and SNRIs that I tried before this drug. It is in a class by itself and unfortunately will probably remain so. This antidepressant gave me back my life, calmed my panic attacks and even helped with social phobia. It is too bad that it has been given such a bad rap that it is hardly prescribed anymore."

10 / 10
Was this helpful?YesNo
75 Report
  • Threse
  • October 29, 2015

For Major Depressive Disorder "I have been dealing with major depression and terrible anxiety for the last 40 years. I had tried at least 6 different antidepressants, none of them really helped until one doctor put me on the nefazodone. Within 3 weeks what a difference, the relief, the sadness the anxiety, the panic feeling all lifted. This medicine pretty much saved my life. To this day I still take it. It's a wonderful medicine. I hope they never take this off the market."

10 / 10
Was this helpful?YesNo
46 Report
  • Decades
  • Taken for 10 years or more
  • February 25, 2019

For Depression "Been on Serzone / Nefazodone 22 years. My liver has been fine for 22 years, this Medicine Saved my Life, and was the only thing that worked for me ! Right now it is on Manufacturer Backorder till April. I got enough to last, it has saved my Life, PLEASE never discontinue this lifesaver for some of us, especially those of us who have been on it long term like me for 22 years"

10 / 10
Was this helpful?YesNo
32 Report
  • venkman
  • Taken for 5 to 10 years
  • December 31, 2020

For Major Depressive Disorder "Hey guys, I just wanted to give you an update. Many of the reviews informing us that nefazodone has temporarily been discontinued, is slightly incorrect. Teva Pharmaceuticals has temporarily stopped making it due to a shortage of its main ingredient. That does not mean it's discontinued as of yet. In the meantime, those of you who need to wean off of it so that you can successfully get on to a new antidepressant, please call around to pharmacies across your city. Many pharmacies other than the one that you currently use, have supplies of it still left in their inventory. I managed to find many pharmacies around where I live, and have been able to get an another months supply so I can wean myself off. Good luck to all of you all, and I pray and hope that they will soon restart manufacturing. I hope this helps"

10 / 10
Was this helpful?YesNo
23 Report
  • Huggy...
  • November 18, 2020

For Anxiety "A close friend of mine and I have been on nefazadone 50mg for 20+ years. It has been a life saver.we cannot tolerate any other anti depressant or anti anxiety medication. Now we are experiencing a shortage of the 50’s. Wondering if we can group together to let Teva know that we depend on this drug. I called Teva to find out the availability but all the representative would say is there is an ingredient that has been difficult to obtain to make nefazadone . She would not give me anymore information. Wondering if we group together and let Teva know how important and necessary this drug is to us. Don’t know how to get this going. Please help."

10 / 10
Was this helpful?YesNo
23 Report
  • marky...
  • December 17, 2009

Serzone (nefazodone) for Depression "I started taking this drug for chronic daily headaches in 1999. Turns out they were caused by stress & serious depression. The Serzone was a miracle drug for me! I saw the world so much more clearly and without the negative lens. My headaches were gone (turns out it actually has a patent for preventing migraines!). I was on it for 8 years until I moved to a new city and had trouble finding doctors to write for it. So I was off it the last two years, and my doctor had me on awful Depakote instead. I hated it! I found a doctor this week to put me back on Nefazodone (Serzone). I look forward to ramping up the dosage and feeling alive again! It was a great drug for me without sexual side effects, which is important to many men."

10 / 10
Was this helpful?YesNo
65 Report
  • Teton
  • December 24, 2017

Serzone (nefazodone) for Depression "I was in a major depression after my baby died in the second trimester. Thoughts of suicide, the works. When I finally reached out for help I was put on serzone....truly a miracle drug. I was young, 28 and never had side effects. After a year I weaned off. Three years later I had my daughter and started spiralling downward, post partum - after you have a baby it is supposed to be the happiest time! I reached out for help and could no longer obtain serzone. I have literally been on EVERY antidepressant for the past 16 years. Nothing has worked like serzone. I am in a bad spot depression-wise again and am thinking it will be worth the liver risk to try to feel normal again."

10 / 10
Was this helpful?YesNo
34 Report
  • mabe
  • December 10, 2009

Serzone (nefazodone) for Panic Disorder "I was having many panic attacks and could barely manage my life. I started Serzone with the few side effects of dry mouth, sleepiness at first, and constipation. Only the dry mouth remains. I have now been on it ten years through many major stress issues. It has kept me functional through all these, and I have avoided breakdowns that could have occurred. (On measures of stress tests, I usually rank in the "Go to the Hospital" area). No liver problems, and it is tested yearly. I have had to slightly up the dosage two years ago. I did have a horrible time in trying to quickly change to another drug when it appeared that serzone was going out of production. I am grateful for it, and wish it was more widely used"

9 / 10
Was this helpful?YesNo
62 Report
  • NCCHICK
  • July 8, 2009

Serzone (nefazodone) for Depression "I have just started on Serzone (Nefazodone) after reading up on it. I have tried so many other SSRI's that did not work so I am hoping that this class of drug will. I wish people wouldn't worry about the the liver issue. Depakote and Cymbalta both have the same risk but they haven't been pulled off the market due to the bad rap. I decided to try Serzone regardless of the liver issue. I will have my liver checked at least every 6 months and if it becomes abnormal, I will stop taking Serzone. No big deal. It is as simple as that. But I read that the risk is only about 1 in 250,000. I will take those odds if this drug really helps me. So far I feel drowsy but I can live with that. The alternative is debilitating fatigue and horrible negativity."

9 / 10
Was this helpful?YesNo
60 Report
  • OCD
  • Taken for 10 years or more
  • July 29, 2021

For Anxiety "Teva NEEDS to get its act together and get this drug back on the market! I have taken this off-label for OCD for 12 years and it is the *only* thing that works for me. My psych put me on Trazodone after I ran out of Nefazodone and it is not even close to the same thing. I'm close to quitting my job because my condition is degenerating so badly. Before Nefazodone I tried every SSRI and tricyclic in the book and nothing worked. My psych made sure I understood the (tiny) risk when he put me on Nefazodone. Teva, please please PLEASE fix this, real people are suffering!"

10 / 10
Was this helpful?YesNo
17 Report
  • Anonymous
  • September 21, 2009

Serzone (nefazodone) for Depression "Serzone is the only one that has helped me and I've never had any liver problems that are associated with it. It makes me feel better right away. Really though I am certifiably depressed and it works. If nothing else works then try this. If the ones you are on work, then by all means don't, thanks."

9 / 10
Was this helpful?YesNo
57 Report
  • xjb99mr
  • July 17, 2015

For Depression "Nefazodone changed my life. I have taken it for 17 years. Within ten days of first taking it, I stopped dwelling on negative things in life, found myself laughing more thanI had since I was a teen. And, my communication skills increased dramatically. No more brain farts, searching for words from time to time. I get blood tests 4 times a year to be liver safe. Nefazodone taken in evening,helps you sleep too. It's a wonder drug"

10 / 10
Was this helpful?YesNo
36 Report
  • Jackie
  • June 8, 2023

For Anxiety "I have taken this drug for many years. I’ve tried many others before, and all they did was cause dizziness or more anxiety for me. When they took this off the market, I struggled to live my life normally. I have not been the same!! When I found out that they were manufacturing it again I was so relieved! I just had my doctor fill it for me and I am a happy camper. I had agoraphobia for 7 years before they put me on Nefazodone . I can’t begin to tell you what I went through with two young children to take of. But I found a self help group and this medication saved my life‼️"

10 / 10
Was this helpful?YesNo
7 Report
  • Mark
  • Taken for 10 years or more
  • September 5, 2019

For Anxiety "I had debilitating anxiety and was prescribed Nefazodone. I have experienced no side affects as far as I can tell and almost perfect relief. I'm back to normal. I only need 100 mg a day. When I'm very stressed I sometimes have to take another 50 mg."

10 / 10
Was this helpful?YesNo
22 Report
  • Nefaz...
  • Taken for 10 years or more
  • January 15, 2022

For Anxiety "After trying several antidepressants and anti anxiety meds my psychiatrist gave me Nefazadone. It saved my life! I went from having almost daily panic attacks to none. Severe depression to mild at times. I got my life back and was able to function! This was 20 years ago and still doing well. This is a unique medication and usually works when others fail. My only side effect was some visual effects for about 3 months. There has been a shortage recently but now it’s back and I am so grateful! If your dr. is concerned about liver problems do not be discouraged! Unfortunately this drug got a bad rap from its brand name serzone years ago. It is no more dangerous than many other antidepressants and medications on the market including Tylenol. Hope this helps someone like it did me."

10 / 10
Was this helpful?YesNo
13 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.