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Xyzal for Allergies User Reviews (Page 4)

Xyzal has an average rating of 4.6 out of 10 from a total of 165 reviews for the treatment of Allergies. 32% of reviewers reported a positive experience, while 53% reported a negative experience.

Reviews for Xyzal

  • Pauser
  • Taken for less than 1 month
  • June 10, 2017

"I took this three days ago and was up all night. I didn't make the connection as I had a cup of coffee later in the evening than I normally would. I took another Xyzal the following day. I still have not slept. I have been up for 3 nights!!! I have a heavy duty sleeping pill that I am going to take tonight and I'm hoping that will be the end of it. I can't imagine it would take longer than 72 hours to make its way out of my system. If you are someone who experiences these types symptoms with certain medications, avoid Xyzal."

1 / 10
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16 Report
  • Jewel...
  • November 16, 2017

"I wanted to share my experience with taking this medication. I started taking this medicine and felt a little better with the allergies however, I noticed my mood had changed. I started feeling very depressed about a week into the medicine and that is NOT like me at all. I am usually someone who wakes up with a burst of energy and always in a good mood. My allergy symptoms were improving a little bit but now I am in a state of depression. I was having mood swings and mentally breaking down crying for reasons that I usually wouldn't cry about. I talked with my doctor and we agreed that the medicine was making me feel this way. Today is day 4 without taking the medicine and I am back to my normal bubbly self. No more Xzyal for me."

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15 Report
  • Sotabby
  • October 18, 2009

"I have severe allergies indoor and out. I cough constantly due to post nasal drip and irritated throat. I took Xyzal and within hours the coughing stopped! I ran out of pills and took Allegra. The coughing came back the same day. The coughing doesn't go down well with everyone being fearful of the Swine Flu! I am so thankful to have found Xyzal."

10 / 10
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26 Report

Frequently asked questions

  • Bette...
  • May 24, 2017

"I have had the worst allergies on record this season. I have tried everything from Claritin to Zyrtec and everything in between. Nothing helped. My post nasal drip was so bad I felt like I had bronchitis from all of the coughing. I even thought I was going to overdose on my albuterol inhaler because I used it so much because I could not breath. A friend recommended Xyzal and brought it to my house one day. The symptoms did not go away all at once but after 2 days on the pill I feel so much better. I take it around 6 pm everyday and I sleep well and wake up perfectly fine the next day. Xyzal has saved me. I hope it lasts and doesn't wear off like Claritin."

9 / 10
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15 Report
  • Aller...
  • October 5, 2017

"I never tried this product because I am allergic to microcrystalline cellulose. The cellulose can cause gut pain, inflammation and sometimes itching. Watch for products that use this filler. Even some prescription drugs use this filler. Be aware of the inactive ingredients in what you take."

1 / 10
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14 Report

Are you taking this medicine?

  • holly...
  • September 26, 2017

"The instructions say that you should take it at night as it can cause drowsiness; however, this medication kept me up all night! It also made me feel anxious and weird. And to top it all off, I am still suffering from allergies. Guess it's time to try something else."

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  • Cpm
  • Taken for less than 1 month
  • July 8, 2022

"Healthy adult male, slightly overweight, itchiness from allergies. Half a tablet left me groggy and exhausted for nearly 30 hours. Also some minor chest pains. I cannot risk using it again. It got rid of the itchiness, but the side effects are a big negative"

1 / 10
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  • Anonymous
  • May 28, 2009

"I have a rare skin rash that appears only during summer months. It is an immune system response to heat. Xyzal 10 mg reduces the rash by about 20%, but after about a month, an immunosupressive reaction occurred. I started getting large, painful pimples in weird places like forearm, hand, and neck. Had a similar reaction to Flonase a few years ago. Immune system can't fight the pimples, so they take over. Disappointing because this is the first oral drug to have an effect on the rash. Hay fever gone too."

6 / 10
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  • QMCIII
  • Taken for less than 1 month
  • July 13, 2017

"My doctor suggested this medication for allergies a few days ago. I was taking for two days and I was completed exhausted and wiped out both days (which never happens to me). So I decided to research it and saw that many people had a similar reaction. This was a significant reaction so be careful before you take it. I have now stopped."

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  • wolflew
  • December 9, 2009

"I started using this right after starting immune therapy for indoor and outdoor (perennial) allergies. I had been on Zyrtec and the additional dose of allergans coming from the shots made me miserable with continual sinus mucus draining/blowing; I tried taking Benadryl (on top of the Zyrtec) but that put me to sleep. The Xyzal stopped the allergic reaction, so I'm on it now for the second month with no side effects; and very happy to have it."

9 / 10
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  • sneezee
  • January 30, 2010

"I have chronic sinus allergies and my ENT prescribed Singulair and Allegra 180 mg one tab each per day. These worked fine for me, but my Doctor then asked me to try Xyzal instead of the Allegra, I've been using this new combination for about a month or so, but for me, the Allegra may be more effective, and I don't get the "drowsies" from it as I get with Xyzal. I then did something stupid, I tried being my own doctor, and took (2) Xyzal tabs with my usual 20mg of Singulair. The result being INCREASED histamine and drowsiness... so folks, the moral here is; Don't play Doctor,... abide by your Doctor's instructions... he/she knows best."

8 / 10
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  • puddi...
  • July 27, 2009

"This medicine has helped me through allergy seasons, hives, and hay fever. Most of my family uses it, too. My dad is 56 and he loves it. He goes on and on about how "medicine is so advanced now-a-days" and how it was "back in his day". He says he has never seen anything like it and swears by it. I do, too. It's great!"

10 / 10
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21 Report
  • glenn...
  • May 18, 2017

"I normally use zyrtec liquid gels- the tablets are no where as effective. But they last only about 3 hours. This stuff made me a little groggy, but not when I wanted to sleep, and if it had any allergy effect it was indistinguishable from nothing at all. Waste of money- I had so wanted a longer lasting alternative - NG"

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11 Report
  • Anonymous
  • Taken for 1 to 6 months
  • May 3, 2021

"Wow, so glad I found these comments! I couldn't figure out why some days I feel like a zombie and have to go back to bed. Linking this with when I've taken Zyzol the night before makes so much sense. As far as helping with my allergy symptoms, not so much."

1 / 10
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  • Traope
  • Taken for less than 1 month
  • May 31, 2017

"BAD EXPERIENCE FOR ME. First side effect was tired. Turned into totally wiped out. Lack of energy, feeling sore, then the sore throat! This drug kicked my butt. It's not for me, I want to be outside active.. This drug will keep you on your sofa..... I'm going back to my old faithful. I tried this because of the coupons."

1 / 10
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  • Conce...
  • Taken for less than 1 month
  • August 14, 2019

"Xyzal was prescribed for my daughter by her allergist for abdominal pain & bloating and with hives and itchy mouth after certain foods. Symptoms getting worse over 5 years. Started whole tablet for 3 nights before cutting it in half due to severe drowsiness and slow response time. Ugh. She weighs 105 lb and is 22 yo. She currently complaints of being horribly fatigued all day after 12 hours of sleep. Senior year in college begins next week. Bloating is still occurring as is abdominal pain."

3 / 10
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8 Report
  • Anonymous
  • February 1, 2023

"I have one kidney that I have had two surgeries on, so if I feel pain in my side from a drug, I have to stop taking it. I finally found Xyzal which works great, but I get heart pain from it. I didn’t realize until the second year I took it for seasonal allergies. Then I finally put it together."

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  • Tom
  • Taken for 6 months to 1 year
  • September 30, 2018

"It worked great for me. I get hives and become really itchy near dust. I thought everyone was itchy all the time but it turns out it wasn't normal. The doctor said to take this. It hasn't made me tired or have any mood changes. Though there are barely any medicines that do make me drowsy."

10 / 10
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  • Trlaw...
  • Taken for less than 1 month
  • May 29, 2017

"So I have terrible allergies, which most people on here say they do. I typically use Claritin and Zyrtec. I switch the 2 every other month. Also I use allergy shots. (3 shots every time, which sucks!) Some co-workers of mine mentioned using Xyzal and having good experiences so I decided to try it out. I decided to get the 10 pack first just to try it out since it's so expensive. As far as helping my allergies... the medicine has helped me a lot. The downside is it makes me extremely tired. Basically I better be ready for bed soon after taking it. But I having had any grogginess the next morning. I just wake up feeling really good. But keep in mind, what works for me may or may not work for you. Benedryl and Allegra does nothing for me."

10 / 10
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  • Kayjohn
  • Taken for 1 to 6 months
  • June 1, 2017

"My allergies are terrible, it doesn't matter the season. I have tried Claritin, Zyrtec, you name it I've tried it for my allergies. I finally came sleep at night and wake up without an itchy throat. No more constant sneezing, coughing. I can finally go outside and enjoy the spring time. I have read other reviews of people being tired the next day and I haven't experienced that."

10 / 10
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  • JenRDH
  • Taken for less than 1 month
  • May 22, 2017

"First time using Xyzal last night for allergies. Normally, I take Benadryl but wanted to give this product a try as it's new OTC. I only took half a pill at bedtime. Yes, my allergic symptoms cleared up but WOW did it make me tired. I'm thankful I have the day off as I don't know how I could function at work. I expected some drowsiness but this far exceeds the effect of a full dose of Benadryl."

7 / 10
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  • mikel
  • September 19, 2009

"I have used a lot of different allergy medicines (for dust/mold/pollen) and I have never gotten a side-effect as bad I got from this. I switched from Zyrtec to this because of a discount that was given; I have been on it for close to 10 months and then I started losing my short-term memory, lose creativity, and it even started to make me slur words. I don't blame it entirely on this medicine, it MAY have been the combination of this and Astepro; but in my experience this definitely causes drowsiness. I can't completely say to stay away from it just be sure to monitor it right away and after about 5 months. I switched to Allegra 180mg. Hope this helps."

6 / 10
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17 Report
  • Anonymous
  • Taken for less than 1 month
  • October 13, 2021

"This pill did help my allergies, when Claritin and Zyrtec didn't, but the anxiety I had after a day was the worse I had ever experienced. I have frequent panic attacks, so I know the feeling. I almost went to ER one night. Since stopping, anxiety is back down to normal levels. Unfortunately, the relief isn't worth it."

1 / 10
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  • MBFox
  • Taken for less than 1 month
  • October 16, 2017

"For allergies and allergic reactions this medication worked well. Benadryl had stopped being effective and Claritin has always been useless so I decided to give this a shot. I took it around 5 p.m. and within an hour the misery of the allergies was less and by morning I felt 100% better. Took the product for two weeks until whatever was triggering my allergies finally stopped. No side effects noticed while taking the medication (which for me is rare as I'm allergic to nearly everything). No problems with interactions with heart medication either. Was well worth it."

8 / 10
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  • Joan...
  • Taken for 1 to 6 months
  • May 16, 2023

"Best allergy medication I have tried in 10 years. No drowsiness, no side effects. It's working perfectly. I take one a day, at night, just as it states on the bottle and it's working perfectly. Every once in a while I have to take a sudafed for a little nasal drip when allergies are severe, but that's rare."

10 / 10
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2 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.