Estradiol topical for Dyspareunia User Reviews
Brand names: Vagifem, Estrace Vaginal Cream, Imvexxy, Yuvafem, Estring
Estradiol topical has an average rating of 4.2 out of 10 from a total of 16 reviews for the treatment of Dyspareunia. 25% of reviewers reported a positive experience, while 56% reported a negative experience.
Reviews for Estradiol topical
- kasey
- Taken for 1 to 6 months
- November 16, 2019
Imvexxy (estradiol) "Pros: packaging is better than Yuvafem and Vagifen since it is inserted manually without all those plastic applicators. Cons: The first time I went to renew the Rx they hiked the monthly price by $15 (from $35 to $50). Otherwise I would have continued trying it for longer. Instead I ended up using it for only 8 weeks. The tablet dissolves easily, but that makes for significant discharge overnight. The tablet is pink (they use Red#40) and the discharge stains clothes (needed to use a stainremover) so I needed to use pantiliners at night."
- SassyG
- Taken for 1 to 6 months
- February 13, 2020
Imvexxy (estradiol) "I have been taking Imvexxy 10mg twice a week for 6 months now at night before bedtime. It has not helped at all with painful intercourse and dryness. My dr told me not to expect instant results and to try it for a few months. I had also hoped for at least a small bump in libido, but nothing. I usually get a slight headache the day after using and there is some external burning as well. My hair feels thinner. I don't like having to insert the capsule manually; it's awkward and never feel that I've inserted it far enough. Have not had any of it come out, though. Also feel that I may be starting a yeast infection. This is not for me and I will discontinue after this month."
- Dee
- Taken for 6 months to 1 year
- October 1, 2019
Imvexxy (estradiol) "I took Imvexxy for four months. It is an easy pill to pop in with little mess. However, I think the pill should be white because the pink discharge that you get from the pill could be confused with spotting. Anyway, the medicine worked right away for my pain with sex. However, I could not tolerate the pelvic cramping, breast tenderness, and hair shedding. I had to go off of it because I was too uncomfortable with these side-effects. I am now on Estrace cream and so far no bad side effects, but the only downfall is that it is messy. Ugh. Nothing is ever a perfect fit :)"
- Jean
- Taken for 1 to 6 months
- January 21, 2019
Imvexxy (estradiol) "I had been taking Imvexxy for almost 5 months. I had seen no positive changes. I started having heart palpitations after 3 months of usage. Then I began to notice pain from my fibroid tumors returning. I have discontinued taking this product. I’d rather have painful intercourse then live with fibroid tumors and heart palpitations. I’m wondering how many other women have had these same problems and never reported them."
Are you taking this medicine?
- Ingrid
- Taken for 6 months to 1 year
- August 3, 2020
Imvexxy (estradiol) "Have used Imvexxy for over a year. Dye should NOT be in a vaginal insert. I also have had leakage - with used overnight or during the day. A year on the medication - sex is still extremely painful and atrophy has not improved per my yearly exam. Many issues with getting the pharmacy to properly bill. Now my prescription just went up by more than $11 per month. Called the Imvexxy number and they tell me I have to wait until Jan 2021 to get another discount card. This has been an extremely frustrating experience between fighting to have the discount applied each month, no improvement with the painful sex, and the leakage of the drug."
- col
- June 30, 2020
Imvexxy (estradiol) "Used one Imvexxy tablet. Felt burning. Spotting, which I thought was blood. It was washed out pinkish, but it may have been the pink outside of the tablet. Felt burning for a day or two and will not use again."
- Dee
- Taken for 1 to 6 months
- June 6, 2019
Imvexxy (estradiol) "I have taken Imvexxy for about five months. I took the 4 mcg and it helped. I probably should have taken the 10 mcg for painful sex. However, I had to stop using it-- pelvic cramping, breast tenderness, but the main thing that made me stop was my hair was falling out. I am sad because it was an easy fix for awhile."
- Karen...
- Taken for 1 to 6 months
- April 23, 2020
Imvexxy (estradiol) "Three months on imvexxy now. No issues at all other than a minor itch I had the first month I was on it but the minor issue went away after month two. Now on my third month going into my fourth month and things have been very positive."
- Regis...
- Taken for 6 months to 1 year
- November 7, 2021
Imvexxy (estradiol) "My physician prescribed Premarin vaginal cream, with good results. After a year CVS, my prescription provided, notified me they would no longer cover any of the cost of Premarin and recommended the physician order Imvexxy 10mcg twice a week. Even using this medication faithfully, I have had minimal to no improvement in the dyspareunia and the residual headaches are miserable."
- michblu
- Taken for less than 1 month
- August 20, 2018
Imvexxy (estradiol) "Actually very very impressed with the results. My intercourse went from painful to very pleasurable within days after using imvexxy."
- Joano
- December 28, 2018
Imvexxy (estradiol) "Had abdominal swelling and a headache right away, couldn’t tolerate it; went back to vitamin e suppositories."
- Char
- July 27, 2019
Imvexxy (estradiol) "Did not work for me and gave me headaches."
- No...
- Taken for less than 1 month
- July 23, 2023
Imvexxy (estradiol) "I think the Imvexxy is helping. Sex is more comfortable and there is much less dryness. My vagina feels just younger."
- amand...
- Taken for 1 to 6 months
- May 19, 2020
Imvexxy (estradiol) "All in all everything so far is a very delightful experience"
- Denise
- Taken for less than 1 month
- August 23, 2018
Imvexxy (estradiol) "Really not impressed so far..."
- Helen
- Taken for less than 1 month
- January 20, 2022
Imvexxy (estradiol) "Decided to give it a try first 3 nights no issues then started with migraines the side effects are worse than the treatment not sure I will continue"
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
Learn more about Dyspareunia
Care guides
Symptoms and treatments
Medicine.com guides (external)
More about estradiol topical
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (473)
- Side effects
- Dosage information
- During pregnancy
- Drug class: estrogens
- Breastfeeding
- En español
Patient resources
- Estradiol vaginal local drug information
- Estradiol Vaginal Tablets
- Estradiol Vaginal Cream
- Estradiol Vaginal Insert
- Estradiol Vaginal Ring (Estring)
Other brands
Vagifem, Estrace Vaginal Cream, Imvexxy, Yuvafem, Estring
Professional resources
Other brands
Estrace Vaginal Cream, Yuvafem
Imvexxy (estradiol) "I have been using Imvexxy for 6 months. I use the 10mcg one time per week. I would be fine using the 4 mcg twice per week, but it is easier to use the 10 mcg once per week. One minor side effect I noticed is that sometimes I get a slight pelvic cramping a couple of hours after I insert it. It usually does not last more than a few minutes. Other than that, so far it is working for me. I am finally able to resume intercourse with no issues. Everything feels like it was before menopause. I spent a lot of money on the Mona Lisa touch prior to using Imvexxy and it did not work at all."