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Lexapro for Major Depressive Disorder User Reviews (Page 2)

Lexapro has an average rating of 6.4 out of 10 from a total of 114 reviews for the treatment of Major Depressive Disorder. 48% of reviewers reported a positive experience, while 26% reported a negative experience.

Reviews for Lexapro

  • rk123
  • Taken for 1 to 6 months
  • May 28, 2016

"Lexapro has saved my life. I have been on it for one month and I have gone from a severely depressed recluse full of anger, rage and self hate, not wanting to see or hear from anyone ever. I am back at work, socialising, eating normally, playing sport and am about to book an overseas holiday. I felt some positive effects after two weeks and felt good after one month. Depression and social anxiety has definitely improved. I don't have any constant racing negative thoughts anymore, these disappeared after about a week and a half. I had very minor side effects but it was nothing that wasn't manageable, a few minor headaches and feeling spacey for the first week. I take 10mg at night because it makes me feel tired and I have a great sleep."

10 / 10
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  • leeed...
  • Taken for 5 to 10 years
  • July 14, 2023

"Out of all of the other antidepressants that I have been on, Lexapro was the most successful at keeping me stable and able to slow my negative thoughts down to help me get them under control and recognize them. I am on 20mg 1x/day. I don't notice a difference in taking morning or night, not many side effects aside from (unfortunately) lowering some folks' libido. I do not get tired from it. No real interactions with other meds that I am on."

8 / 10
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11 Report
  • CGI
  • Taken for 6 months to 1 year
  • August 30, 2021

"Oh my God. I feel like I have my life back. When I used to feel stuck and unable to move, just paralyzed in bed, I couldn’t function. Now, I can just get up. I cannot rave enough about this drug. I have my life back. I have goals and ambition and plans for the future again. I tried several different medications and several different doses before settling on 20mg Lexapro, and it’s the only one I never had an adverse reaction to. I will always recommend."

10 / 10
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25 Report

Frequently asked questions

  • Tornado...
  • March 22, 2015

"I have been borderline depressive my entire life, I am now discovering. It finally came to a point in my life where I was spinning internally and out of control. At a normal doctor checkup I began to cry and my doctor handed me tissues and waited. When I was done, he calmly asked okay, tell me what's going on. And I talked. He prescribed 10mg of Lexapro (generic and I can't begin to spell or pronounce it) He told me it would take about a month before symptoms would disappear and peacefulness would return. It didn't take a week and there has been such a change in me. Everyone in my life (including my disagreeable boss!!) has noticed and things are just nicer all the way around. Wish I'd been on this stuff decades ago."

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57 Report
  • Pratesi
  • Taken for 10 years or more
  • February 21, 2021

"I thought this worked great but after 12 years or so I find myself extremely reclusive, apathetic, and lonely. I take this with bupropion for major depression and anxiety (GAD) along with Buspar, trazodone at night for sleep, and 0.5mg clonazepam as needed. I find myself drinking or vaping cannabis to feel happier or more numb and less anxious. I feel alone but often content always being alone. I'm usually very tired and often sad."

5 / 10
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26 Report

Are you taking this medicine?

  • Juxta
  • Taken for less than 1 month
  • December 14, 2019

"I've been on Lexapro for 3 days at 10mg, my doctor prescribed it for my depression and anxiety. Every single day I've taken this, I've had horrible symptoms ranging from blurry vision, headaches, drowsiness, dizziness, disoriented, nausea, confusion, panic attacks, tightness in the chest, my whole body would begin to burn and my hands would tingle. I'd have a weird jerking in my legs, just bad side effects that affected my job and personal relationships. My doctor said she'd see me again in 2 months, but I'm not taking this stuff anymore and I plan to call her in the morning. This is horrible!"

1 / 10
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32 Report
  • kikilu
  • September 16, 2015

"I have been on Lexapro for 5 days now and I feel so much better! I can't believe it! I am not feeling all down in the dumps and the feeling of just not giving a """" about anything. I find that it has helped me with my overeating as well. I am having less of a struggle in the morning with getting up and getting on with my day."

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More FAQ

  • Emster
  • November 9, 2014

"I was a very emotional teenager and couldn't handle small problems. After trauma around the age of 17 I was diagnosed major depressive disorder, anxiety, mood swings and a personality disorder. I started taking escitalopram 10 and of course the first weeks were still as bad as before or even worse but for me it felt like I was already in hell. After a month I felt great! Just as clear head, stable, no running thoughts or emotions and just happy and peaceful. After one and a half year I quit drop by drop in a time lapse of 3 months but I had to start again because all the symptoms came back. It is really hard to just start taking again or to admit you need it. All side effects are in my opinion way nicer than uncontrollable emotions."

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  • Kriss...
  • March 21, 2017

"This changed my entire world.. I'm 21 Female I've been on Lexapro for 3 months now. My experience, there was a very quick change in my life. I was not aware I had major depression, that was the real kicker. I do not remember a time I felt this alive/"normal"/happy/connected."

10 / 10
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39 Report
  • Anonymous
  • Taken for 1 to 2 years
  • June 9, 2019

"OK so I started taking lexapro (5mg) after a horrible experience with Zoloft. When I started taking Lexapro it was to treat anxiety mainly, but also depression. But as my life changed, I got more and more depressed and went to a new therapist she bumped me up to 25 mg. It was a high jump and I just switched one day. Aside from the first month of the up in dosage, which consisted more depression than usual, headaches, body aches, and fatigue- since then I haven’t had any problem with it. Lexapro has helped both my MDD (major depressive disorder) and anxiety a lot. The only thing I’ve noticed is weight loss, fatigue, and hand trembling but none of it is like miserable (on Zoloft I was throwing up and passing out sooo). I have been switched for a while and don’t plan on messing with it. May up my dosage eventually. I hope everyone finds what they need!"

10 / 10
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29 Report
  • Happily...
  • Taken for 6 months to 1 year
  • June 5, 2015

"I have suffered through depression most of my life (I am 16 now) and I have gone through many anti depressants but most left me feeling even more depressed (due to weight gain which is one of my triggers with depression). Lexapro is the only anti depressant I have been on that has not caused excessive crying, weight gain/loss, suicidial thoughts, etc. the only thing I noticed is I sleep a little more than normal but hey, sleep isn't bad for me."

8 / 10
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45 Report
  • Lynn
  • Taken for 5 to 10 years
  • April 30, 2021

"After my daughter was born, I developed severe post partum depression and anxiety. I started Lexapro 20 mg. Now 9 years later, same dose. There is good and bad. My anxiety was much better and I was able to function again. I have dealt with the side effects for 9 years - extreme apathy and carelessness, no natural affection to my family, weight gain. I get in a terrible way when I try to taper off and quit. Very ill physically and mentally. I will likely take it forever."

2 / 10
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20 Report
  • avm
  • October 28, 2014

"Rating - 10 -11 Very good and very effective. Taking Lexapro since 2009. Few problems. Have a very serious depression/minor schizo-psychosis problem. Took generic and am taking Lexapro again. Had a few problems with generic. Don't have same calm reaction with generic. Lexapro puts me in a good mood most of the time. Feeling of equilibrium mentally. Am happier/relaxed/calmer. Does make me very sleepy/drowsy, & a few other minor side effects. Only antidepressant I have had few problems with. Able to be more relaxed. Can fall asleep in a matter of minutes instead of hours. Have had a very good experience with it. Trying to get insurance to pay for it."

10 / 10
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44 Report
  • Honey...
  • Taken for less than 1 month
  • August 27, 2019

"So I just started Lexapro 10mg 10 days ago. I still feel down and depressed, so Dr upped it to 20mg. I've been on that for 2 days and anxiety and crying is intense praying I will get better once my body adjusts to new dosage..anyone else feel this way with dosage change?"

7 / 10
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26 Report
  • bell
  • Taken for 1 to 6 months
  • April 30, 2020

"My first antidepressant I was prescribed, sex drive was at 0, I was on it for a month and as the days went by it got worst, I would say so far being on Lexapro cause one of my worst suicide attempts and my self harm was getting way worst. Immediately got taken off after I had my month checkup."

1 / 10
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23 Report
  • yourl...
  • Taken for 2 to 5 years
  • September 9, 2020

"I had several major behavioral changes including aggression, troubles regulating temperature, decreased appetite, weight loss, and severe withdrawals when decreasing dose and when multiple doses are missed."

3 / 10
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21 Report
  • Julza
  • March 26, 2015

"Lexapro was the first medication for what was first diagnosed as adjustment disorder and later major depressive disorder. Lexapro (escatalopram) had me relaxed within a couple of days. I was so chilled. Any more relaxed and you'd think I was asleep. I have a highly stressed involved workplace where I lead teams of people and I was able to get my patience, communicative persona, positive outlook and collaborative nature back on track. My home life improved immensely. I was able to regain my perspective on the importance of issues meaning I could let small things go. The most important thing is I felt better in myself. I was so happy until two years down the track. Unfortunately it stopped working."

9 / 10
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41 Report
  • Chris...
  • Taken for 1 to 6 months
  • August 31, 2015

"I was really suicidal before I started this and its helped me a LOT. I take this for my anxiety also and I don't find that it helps but it does help with my depression. I had problems with self harm and ripping my hair out before I started lexapro and I haven't relapsed on that. This medication has also helped a ton with my anger issues."

9 / 10
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38 Report
  • cj rose
  • Taken for less than 1 month
  • December 26, 2014

"I have been on Zoloft for 5 years and it was horrible for first 4 months! Then it began to work. But after 5 years and had recently upped to highest dose, it stopped working. So after discussion with psychiatrist, decided to try Lexapro. I was weaning slowly off the Zoloft and was doing good then boom! Horrible brain zaps, unorganized thinking, it was terrible! Psych told me to start with a quarter of a 10mg tab, as I continued to wean of the Zoloft. The very next day was great...no more brain zaps, mood stabilized because the side effects from weaning off Zoloft were gone! I'm now on the full 10mg Lexapro and down to about 10mg of Zoloft. Lexapro is great so far. I am well pleased. I also take 1mg Klonipin twice daily."

10 / 10
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36 Report
  • Itsme
  • Taken for 10 years or more
  • October 9, 2021

"Been on Lexapro for 20 years or more. Had a traumatic situation and I needed additional help. Drs put me on two different meds and took me of Lexapro. Last week I'm back on my original 10mg and going through the ramp up period. I'm going through constant crying (not uncommon for me), fatigue, and trying to get through the day. Lexapro worked wonders for me for all those years, I'm so hoping that I'll be back me again soon."

10 / 10
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14 Report
  • mh1214
  • Taken for less than 1 month
  • December 6, 2015

"Was once on Lexapro 20mg many years ago. Stopped taking because of pregnancies. Been 20 months since my youngest was born and started to struggle badly. I finally caved in and went back in them. Have been on them now 12 days and still get a bit of nausea and always tired. Constant yawning. But mentally I have been great! I do feel a little dull in the emotions part but to be honest its better than it was before. Hopefully the side effects subside :)"

8 / 10
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33 Report
  • Coryman
  • Taken for 6 months to 1 year
  • September 2, 2018

"I suffer from Schizoaffective disorder which is like schizophrenia combined with Major Depressive Disorder, and I take Lexapro as my anti-depressant/SSRI and so far love it. Been on it for about 1 year and what it does for me is lessen anxiety, prevents panic attacks, prevents traumatic flashbacks, AND controls my depression and prevents me from harming myself. So I have nothing but good things to say about Lexapro. Before this I was on Celexa but that had stopped working after a number of years. My psychiatrist explained Lexapro is supposed to be a newer form of Celexa that is more effective and fewer side effects, and based on my experience on this medication I would have to agree with that."

10 / 10
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24 Report
  • Lucy...
  • Taken for 6 months to 1 year
  • August 5, 2016

"Lexapro has been the only antidepressant I've taken that has alleviated my depression at all. It worked well for me and it started working within 2 days! I could laugh again and my anxiety went down. I took 20 mg daily. Unfortunately, within 6 months I gained 25 lbs! That was the only drawback and I had to stop taking it bc of the weight gain. The first couple times I took it, everything looked fuzzy and psychedelic but that went away quickly. I'd say it's definitely worth a try if you're depressed or anxious."

8 / 10
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30 Report
  • roooo...
  • Taken for 1 to 6 months
  • March 14, 2024

"Hello everyone, I've been on many antidepressants during the last 7 years, all SSRIs, SNRIs, and NDRI (Wellbutrin). So tomorrow will be the third time I will try Cipralex for my MDD. The last 2 times the benefits outweighed the negative side effects, I would say it made a difference for anxiety and also gave me some energy to get things done, things were not perfect, but overall I was feeling better. I was an anxious wreck all my teen years, Lexapro helped my GAD and SAD. For those who want to start this medication, all I can say, be brave enough and try it because it's a life-changer for many of us!"

8 / 10
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  • Shuler
  • Taken for less than 1 month
  • December 16, 2017

"My husband is a retired veteran from the Army he has PTSD, depression and anxiety. I introduced my husband to Lexapro which I have taken over the years. I have seen a big change in my husband, and I am thankful. He has stated that I saved his life by introducing him to this medicine. Finally my husband can enjoy life again. Lexapro is an amazing drug anyone out there who suffers from PTSD anxiety or depression I highly suggest you give this medicine to try talk to your Doctor. I for one can say it saved my husband's life"

10 / 10
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25 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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