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Duloxetine for Anxiety User Reviews (Page 5)

Brand names: Cymbalta, Drizalma Sprinkle, Irenka

Duloxetine has an average rating of 6.4 out of 10 from a total of 385 reviews for the treatment of Anxiety. 57% of reviewers reported a positive experience, while 30% reported a negative experience.

Reviews for Duloxetine

  • Lonely
  • July 12, 2016

Cymbalta (duloxetine) "I'm on at this time 1mg alprazalam 3×a day. And Cymbalta 60 milligrams once a day ever since I started taking the Cymbalta my anxiety my mood my pain it all feels way better. I used to take 8 or as many as I needed bars a day for my anxiety. Finally got into a psychiatrist I was so freaked out that they were going to prescribe me Xanax for anxiety because doctors are so blah blah blah about it because people screw it up for people like me that need it well the Cymbalta lowered my Xanax use basically in half I think it's really more mental on my part and the Cymbalta has been really good for me I had one time that I went off of it for 2 days because I couldn't make it to the pharmacy and yes my anxiety came back in full-blown anxiety."

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  • Hiii
  • Taken for 1 to 6 months
  • June 16, 2023

Cymbalta (duloxetine) "Here’s my review. I don’t like it. I don’t care what psychiatrist thinks. I know my body. If my body doesn’t tolerate it then it’s not for me. Stop demonizing stimulants like Adderall that work. Too many people not properly diagnosed and put on wrong medication."

1 / 10
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  • Kelsey
  • Taken for 1 to 2 years
  • September 4, 2020

Cymbalta (duloxetine) "I have been on cymbalta 30 mg for about a year and a half for anxiety. When I first started taking it I could not stay awake. If I sat down and got still I was asleep. After about 3 months that started wearing off (never fully). I have also had muscle spasms since I started and they have not went away. I recently started having panic attacks and couldn’t seem to focus at all. I talked to my dr about switching meds, they decided that moving to 60mg would help my anxiety more. I took 60 mg for about a week and was having so many more muscle spasms. I also had headaches everyday. I felt all over the place. So I went to my dr again saying I thought I need something else. I will start taking Wellbutrin. I really hope this is going to be the medicine for me. My anxiety is out of control right now coming off cymbalta. I also am having a ton of dizziness."

3 / 10
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Frequently asked questions

  • Christy
  • September 22, 2019

Cymbalta (duloxetine) "It worked for me at the beginning in 2017 I went from 60mg to 30mg.I was on it for anxiety. But after a year it really wasn't working, made me very moody and snappy. It actually was giving me more panic attacks and diahrrea. The worst to get off it. Worst symptoms I experienced, I felt better off of it. I feel like got worse after this medication."

2 / 10
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  • Kiyoty
  • October 3, 2016

Cymbalta (duloxetine) "I just started Cymbalta about 2 weeks ago and so far it has been great-My anxiety was really bad for months, leading to severe depression, and I finally had to talk to my doctor about taking something-I was reluctant about taking anything and hadn't before now-I am so glad I did! I take 30 mg now 1x day and like the lower dose-Initially had a couple a bad reactions-after 12 hrs of my first pill, I got severely hyper but it settled about 6 hrs later then I took a day off and restarted-it's been fine ever since-I can't explain how great it feels to not have those negative thoughts constantly harass you and the renewed sense of self and confidence is over-whelming. I only noticed dry mouth and I'm more forgetful it seems."

9 / 10
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Are you taking this medicine?

  • Slash
  • Taken for 1 to 6 months
  • October 28, 2019

Cymbalta (duloxetine) "I was recently switched to Cymbalta for bipolar disorder, severe anxiety, and unbelievable nerve pain! Having Fibromyalgia I was willing to try a almost anything! The drug is marketed for ANXIETY and NERVE PAIN... I can only speak for myself, but Cymbalta HAS NOT... in any way... worked for for either!! Depression... seemed to help that. The drug indications list the worst of my symptoms, with absolutely NO benefit for me !! It's a fraudulent way pharmaceutical companies have to market their product. ITS A JOKE!!"

3 / 10
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  • Carol...
  • February 4, 2021

Cymbalta (duloxetine) "I took Cymbalta for only 4 days and had to get off of it. Even with taking 1.5mg of Xanax a day, I could not get over my extreme anxiety and jitteriness. I was constantly in my head and experiencing horrible physical symptoms like heart palpitations, sweating, hot flashes and nausea and having to go to the bathroom frequently. Panic symptoms would crop up like every 2 hours and I felt like the Xanax was barely doing anything for me to stop the anxiety. This was the worst medication I have been on by far!"

1 / 10
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More FAQ

  • Bryan
  • Taken for less than 1 month
  • April 9, 2019

Cymbalta (duloxetine) "I started on 30 mgs a day and stopped on the 5th day. I felt so nauseous and intestinally challenged. The drug also caused my heart to go into afib / aflutter with moderate tachycardia. As soon as I told the Doctor what was happening he had me stop immediately. Now I am waiting to see a cardiologist to assess the arrhythmia situation. I know the literature says that my side affects are rare, but it happened to me."

1 / 10
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  • Misty
  • Taken for less than 1 month
  • September 7, 2019

"I am SO HAPPY I took the jump and tried this medicine!!! I have been put on several different antidepressants and anxiety meds and nothing has worked. I have been on duloxetine for 2 weeks now and feel AMAZING! I was nervous to take this medicine due to the poor reviews. Don’t let those get you down. This could be your miracle drug. I can function so much better now. I have the drive to clean my house now, I can take care of the kids and not feel anxious with the tasks of everyday life. My OCD is also much better. Barely any intrusive thoughts and when they do come they are easy to shoo away. I hope this medicine continues to work the way it is. I haven’t felt this relaxed in years!!!"

10 / 10
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  • Ame
  • November 5, 2017

Cymbalta (duloxetine) "I tried to go about my life without being on an antidepressant, but life didn’t seem very liveable anymore. I tried Lexapro, and though it stopped the heart pounding and shortness of breath, I was still very depressed and always exhausted. I also went from 130 to 150 pounds in about 2 months. I switched to Cymbalta and everything changed, I have never been happier. I wake up full of energy, which is something I have never had. I have also lost the weight I gained! Like others have said, everyone is different and medications will affect you differently. I was surprised to hear my friend had a bad experience with it. I very much recommend at least trying because it has helped me so much!"

10 / 10
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  • Lwes
  • Taken for 1 to 6 months
  • March 31, 2024

Cymbalta (duloxetine) "It saved my life. It was the last thing I tried and it was different than SSRIs. I have no issues on it but it wiped away my daily anxiety and I feel like a person again. It took 2 weeks to kick in and one day I woke up without a panic attack and I’ve been able to change my life since. Try it if you’ve tried everything else."

10 / 10
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  • MoniP
  • January 12, 2019

"Duloxetine/cymbalta- I used this for about 8 years. It was to help me with my anxiety, depression and racing thoughts- I have to say, it worked amazing, but if I missed even a day I could feel the effects. It helped me so much that I eventually wanted to get off of it. I weaned myself off of this slowly. And had a great outcome. I've read so many posts about how awful getting off this drug can be so I was super scared to even attempt it.. but I knew I didn’t want to depend on it forever. I never got sick or had horrible withdrawals. I want everyone to know that even though some people had a bad experience with it, Not all of us did! It worked great for me while I needed it and when I was done and didn’t want it anymore I got off it just fine!"

9 / 10
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  • still...
  • Taken for less than 1 month
  • April 9, 2018

Cymbalta (duloxetine) "After my first dose of the generic version of Cymbalta yesterday evening for major anxiety and minor depression. I was surprised to feel a difference within a few hours. My mood lifted and I had more energy. I still felt slightly anxious. Initial side effects: quite bad insomnia, slight jitteriness, slight diarrhea, very slight confusion at times and nausea for the first 12 hours after taking it. After 2 weeks, I now have zero side effects and have changed to taking it in the mornings. It is a miracle drug for my depression! The constant dark feeling of sadness has lifted completely. It has also helped my anxiety quite a lot, however I still have periods of anxiousness. I am definitely going to stay on this medication as it has drastically improved the quality of my life."

10 / 10
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  • KIWI
  • December 21, 2008

Cymbalta (duloxetine) "Cymbalta is a god send for me and all those people out there who suffer from depression, anxiety, bipolar disorder, diabetic nerve damage, fibromyalgia, pain or what ever else it is used for. I myself have s. A. D [social anxiety disorder] and at times depression. I was taking zoloft and I still felt the anxiety so my doctor prescribed cymbalta and it took about a week 2 actually kick in and when it did I felt it and loved it and would recommend this medication to those who are trying to find a way to help them live there life with ease. It's not a cure but it is very helpful as long as you take it when you are supposed to. Cymbalta is the best. Thanks."

10 / 10
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  • Letty...
  • September 1, 2015

Cymbalta (duloxetine) "I took my first and last 30mg dose of Cymbalta yesterday. The side effects were just unbearable. Dry mouth, blurred vision, tremors, panic attacks, vomiting. I will never take it again. And now today, after only having took one pill and discontinuing, I am having body aches and extreme fatigue. There has to be a better way to beat this anxiety than poisoning ourselves."

1 / 10
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  • zionf...
  • Taken for 1 to 6 months
  • October 3, 2016

Cymbalta (duloxetine) "I'm taking Duloxetine 20mg per day for anxiety and minor depression. I have taken this med for almost two months and keep a daily journal. As a 'blind study' I started this drug without my wife's knowledge. I noticed a decrease in my overall anxiety in ten (10) days and my wife mentioned my calmness in two weeks. I am a 70 year old male and I supplement Duloxetine with Buspar on an 'as needed' basis for anxiety. The Duloxetine seems to smooth things out without the numbing effect of a benzodiazepine. I'm on the minimum available dosage and will soon ask my PCP to up my dosage to 40mg per day. There have been absolutely no bad side effects from the drug."

8 / 10
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  • Anonymous
  • June 16, 2009

Cymbalta (duloxetine) "I've been taking this medication for 3 weeks. First week I was on 30 mg, I felt almost immediate relief from my anxiety/depression. The first six days I experienced fatigue and slept 12 hours a day. By 7th day I was sleeping less and feeling more emotionally balanced. Second week, my dosage was increased to 60 mg and the same thing happened. I slept 12 for about 6 days and by the 7th day I felt good and was sleeping normally. I do have some clenching of my jaw and dry mouth, but a glass of water seems to help. I take my medication at the same time every morning after eating and drink lots of water throughout the day. I'm not taking any other drugs. I've found great relief with Cymbalta. My husband is thrilled with the calmer, happier me. Me too!"

7 / 10
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  • Lisapl
  • January 9, 2017

Cymbalta (duloxetine) "I'm on cymbalta 30mg for my anxiety and depression and I have been on it for a month I have no side effects but nausea and being tired but that all went away in about 2 weeks but great meds works great for me"

10 / 10
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  • Anonymous
  • January 16, 2017

Cymbalta (duloxetine) "First day I took the first 20mg capsule...thought I was going to have a seizure and was having a full blown panic attack. She had given me this for anxiety and for pain (didn't help either: in fact made BOTH the pain and anxiety worse) I couldn't sleep that night. I was supposed to try it for 3 weeks before she upped my dose but I said no way. I threw the bottle away and don't ever want to put one in my body again. It almost strangely reminded me of being on a stimulant (adderall or vyvanse) but it wasn't pleasant or made me focus. I was extremely distracted and panicking so much. I cried for hours."

1 / 10
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  • Jezy
  • January 6, 2017

Cymbalta (duloxetine) "Just started taking this med 5 days ago after 5 years on Celexa. Celexa always left me at an "I'm fine" state and I just said that "I just am older, so I shouldn't expect to have the energy I had in high school" (I'm 26). Two months ago, my meds seemed to stop working all together. My doc decided we should counter-taper meds between Celexa and Cymbalta. Day one of Cymbalta on the lowest dose, I felt absolutely amazing. I have all of my full range of emotions and so much energy and concentration! For about 8 hours on Day 2, my eyebrow would twitch on and off, but that's gone. I'm planning on discussing with my doc about keeping the low dose (he suggested one up) and just completely getting rid of Celexa and see how that works. I'm ecstatic!"

8 / 10
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  • Ken
  • Taken for less than 1 month
  • June 21, 2019

Cymbalta (duloxetine) "This medication really did work, and helped me with my anxiety, it increased my appetite, I was talkative, but... It turned me into a complete douche bag, I would scream at people and completely lose it after something insignificant happened, I was in a dark place and always on the edge."

4 / 10
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  • OCDAn...
  • Taken for 1 to 2 years
  • December 2, 2013

Cymbalta (duloxetine) "Cymbalta worked somewhat on my obsessive compulsive disorder, anxiety and depression better than other medicines. However, I felt like I couldn't do much. I had zero energy even though I took my dose (60mgs) at night. It became too tiring to even make myself something to eat. I did not want to go anywhere or do anything because I didn't have the energy. At higher doses (90 mgs), I had stomach upset and pains if I did not take my dose with food. I would also have diarrhea/loose stools at the higher dose. Sexual side effects were decreased interest and desire in sex. Could be attributed to just not having the energy to enjoy it. It did help with my OCD and lowered my anxiety but did not help my depression."

6 / 10
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  • Pursuit
  • Taken for 6 months to 1 year
  • February 11, 2019

Cymbalta (duloxetine) "I've had GAD pretty much all my life but developed increasing depression and withdrawal from social activities. Finally I bit the bullet and told my doctor. He started me on duloxetine, 30 mg with the warnings about weight gain and sexual dysfunction and commented we could increase to 60 mg in three or four weeks if needed. Never needed the increase - 30mg is perfect. I have gained 4 or 5 pounds. I did notice the sexual dysfunction (loss of interest and difficulty "finishing" at first so I would hold my meds a day or two before bath and treat night which worked fine. Pretty much back to normal in that regard. The best thing is I can get more than one or two errands completed now. I call my pills "do lots of things" now!"

9 / 10
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  • Stefan...
  • April 5, 2012

Cymbalta (duloxetine) "I love this medicine! My anxiety started off as mild and as years past slowly got worse. I went from having social anxiety to generalized anxiety and then major depression. It took me 7 years to find this medicine but once I found it I gained my life back. Still have a little anxiety but most is gone. This medicine was great for my major depression. Yes it does have some side effects but most will disappear with time and like most other users will vouch, the benefits far outweigh the side mild side effects. "

9 / 10
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  • Momma...
  • Taken for 1 to 6 months
  • February 17, 2023

Cymbalta (duloxetine) "All I can say is wow wow WOW! Since my early 20’s I have been on several antidepressants/anti-anxiety medications because well… genetics. LOL Zoloft was awful and made me extremely depressed, Effexor was okay but it had side effects and getting off of was so awful that it scared me from ever using a antidepressant again. Wellbutrin worked decent for a while but i developed resistance, and I had trouble sleeping on it. Cymbalta is HANDS DOWN the best psychotropic medication I have ever taken. I was on 20mg for a month and started 30mg today. The effects started within a few days, literally! Since day 4 or 5 on it my DAILY anxiety attacks and panic attacks for months are GONE. I’m getting out of the house again. In terms of my depression, I have hope for the future, and no longer wish I could disappear off the earth on a daily basis. I don’t realize how dark things felt for me before starting Cymbalta. This may not work for everyone but this medication has saved me."

9 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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