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Prolia for Osteoporosis User Reviews (Page 2)

Prolia has an average rating of 2.7 out of 10 from a total of 322 reviews for the treatment of Osteoporosis. 15% of reviewers reported a positive experience, while 78% reported a negative experience.

Reviews for Prolia

  • bbass...
  • June 22, 2021

"I had my first injection in April 2021 and started having side effects right after—severe headaches, muscle pain, and dizziness. It has been 2 months now, and my bp has gone up, severe headaches, hip pain, and every muscle in my body aches. I was told by the doctor that this was unrelated to the Prolia. I had none of these until I had the injection. I will never take this again and be warned—this is a horrible drug and should be taken off the market. I suffer daily and do not know how long this horrible drug will stay in my body and give me side effects. I live in severe pain every day, and my doctor had to increase my pain meds. There are days I feel like I am never going to be the same person! Please read all about this horrible drug and do not listen to your doctor as it is horrible!"

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  • Jo M
  • Taken for 6 months to 1 year
  • June 12, 2023

"I was a very fit 87 year old lady, living independently, walking 2 km a day, etc etc. Three weeks ago I had a 6 month renewal Prolia injection. I am now a cripple, hardly able to walk. This is a dangerous drug."

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  • Anonymous
  • March 30, 2012

"I've been on Prolia for just over 1 year. Just had my 3rd shot. It is so much easier than taking pills, which I did have problems with. I will get another bone scan this fall and will find out how I am doing on Prolia. I love that it is just every 6 months. Pretty much painless shot. No side effects at all."

10 / 10
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Frequently asked questions

  • David
  • February 2, 2020

"My mother stopped taking because her teeth started to fall out. Within a few months, her back broke and then it broke over the next year, broke a total of four times. I’ve read hundreds of similar stories, and a class action needs to be started to get this drug off the street and to collect damages for families. Let’s start putting together a pool of people."

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  • Judy...
  • Taken for 1 to 6 months
  • June 7, 2023

"I had my first Prolia injection April 5th, 2023. I was so hopeful it would help my bones. Instead it made my life worse! I feel terrible. My bones hurt, I have pains in my body where I never had pain before. Muscle aches and cramps. I feel so tired all the time. I'm 80 but I am constantly on the go. I do most of our yard, take care of the car and our own home. It is a large home and takes a lot of time. I also am blessed to have a great husband and a cute dog who loves to take walks. I struggle taking care of all of it now. In May I had a terrible bladder infection. Still not completely over it. I did research on Prolia but did not do enough. I finally got a sheet listing all the side effects. It is a whole page! It is then I started to put two and two together. I am NOT going to take another shot. It is not good for me. I am looking into other ways to improve my bones. Be ware! Prolia is not good for you!"

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Are you taking this medicine?

  • SuzQ
  • Taken for 1 to 2 years
  • January 29, 2020

"I'm 71 years old. After two hip replacements, my orthopedic surgeon placed me on Prolia in the summer of 2017 in order to build bone density. Bone density was reversed and I was pleased. It's January 2020, and now the side effects are beginning. I'm feeling severe jaw bone pain. After an MRI of my jaw, it's determined I've lost bone density in my jaw, my gums are very sore, and now I'm being treated with laser surgery. My dental implants will need to be removed by the oral surgeon within 6 months. Ladies, what do we do now and Amgen...Where are you?"

3 / 10
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  • Skeeter
  • Taken for 1 to 2 years
  • May 11, 2021

"I blame Prolia for my late wife's death. She died from cervical cancer at 72 even though she had a hysterectomy at 30. I think it lowered her immune system so much that she could not fight off the cancer. Even though the doctor knew she had a thyroidectomy at 31, she still administered the Prolia injections. I would urge everyone to stay away from it."

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More FAQ

  • MDano
  • February 6, 2020

"I have had two Prolia shots and the third one will be due in March. Right from the outset, I experienced bone pain through my hips and down both thighs. Fit, healthy, and active, I have had to force myself up flights of stairs. I notice that in the past couple of weeks, the pain in my legs has taken on a burning sensation and has moved down to my shins. I get out of chairs as if I have arthritis. Absolutely ridiculous! I am going to my GP tomorrow to let him know I have finished with this drug. I saw an endocrine specialist who reluctantly wrote me up for a bone scan later in the year, 'because we know this drug works, we don't need to do scans.' Well, I will continue to take my good calcium supplement and D3 (5,000u a day) and hopefully can get back to running and walking the long distances I did easily prior to these injections. I have two friends on the injections with no problems. A third has just had her first one, and nothing adverse yet!"

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  • LMano
  • July 29, 2019

"I am a 45-year-old female with severe osteoporosis of the spine, osteopenia of the femur and hips. I took Prolia in September of last year and it will be the one and only time that I take it! I was sick within two months of taking this drug! I have been running a fever nonstop, terrible headaches, abdominal pain, nausea and vomiting, weakness in legs, joint pain, and rashes! This drug is so bad! My life has been turned upside down with this sickness from Prolia, numerous ER visits, doctor appointments, and missing work. I am a single mother who couldn’t afford any of this. PLEASE DO NOT TAKE THIS DRUG!"

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  • Never...
  • July 20, 2019

"Had my first shot of Prolia on 4/4/2019 and will never have another one. Side effect started with 14 days. Red hot blotches under my arms on my hips night sweats, day time chills and pain that has impacted on my life dramatically. All this started with a Bone Density Scan that you have when you turn 70 was told I had a high fracture risk and Prolia would help. I am very active ran 10k a day until 6 years ago when I started have problem with osteoarthritis in my knees stopped running, took up walking 10k instead but since this injection have found it extremely difficult pain and fatigue. Please if anyone is thinking of taking this poison do not. Do your own research when a doctor tells you a drug will work, go off and do some research before you take it. Doctors don’t advise side effects then when you go back to see the Dr you're an oddity because all their other patients on this poison don’t have side effects."

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  • Another...
  • Taken for 1 to 6 months
  • October 10, 2019

"First time I was asked about taking Prolia, I refused, having read all the side effects. My bone density test was a little better than the previous one 2 years prior. Wasn't warned about the cost that insurance didn't cover, even though I asked to be notified of my copay. My doctor talked me into it and I'm so sorry. Constipation was totally out of control even with medication for it. I started with the leg pain and hip pain waking me up at night! And all of a sudden, my dental health totally went down the tubes! Also, I had times of nausea for no reason. I have always had no trouble sleeping until the shot. Now that I have read extensively about the side effects, I am refusing it. Did I mention I was healthy, on no meds, and do weight exercises and cardio classes along with some yoga, and 76 years old. Hoping some of the side effects go away! So sorry I agreed to take this!"

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  • Can_t...
  • December 25, 2019

"I have years (30+) dealing with Fibromyalgia, Osteoarthritis in every joint, chronic pain, anxiety and doctors that seem to feel my suffering is better than having any quality of life because the side effects of those remedies may mean physical dependence. So at 53 years old, a diagnosis of osteoporosis so MD says let's go with Prolia. I figure the doctors are finally taking my health as seriously as I do. I have never felt more exhausted, heavy chest crushing chest pain, high blood pressure, tachycardia and exercise intolerance where I cannot even climb a flight of stairs. Multiple emergency room visits and sent home like a hypochondriac. Started pretty much with the first Prolia injection and there will not be a second. I only hope I do not have a major coronary event before this thing wears off. I have a high-stress nurse manager job that I have always been able to manage. This treatment sucks and I would rather break every bone in my body due to the OP than go through this a moment longer than I have to."

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  • Dani
  • Taken for 1 to 2 years
  • August 10, 2019

"I just had my second Prolia shot and it has been a nightmare. My doctor did not tell me about the perils of stopping this drug. I feel like a street drug addict. I have had severe bone pain. I cannot keep my calcium level at a correct level. When I report other numerous side effects to my doctor, he says it was not the Prolia. Now I find out that doctors are getting paid to prescribe Prolia. This is a medical nightmare that will not end. DO NOT TAKE THIS NO MATTER WHAT A GREEDY DOCTOR TELLS YOU."

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  • Aliem...
  • Taken for 5 to 10 years
  • October 27, 2019

"OMG, having read some of these comments, I'm more convinced than ever that my symptoms are Prolia related!! I have lost count of how many doctors/specialists I have seen. Rheumatologists, Endocrinologists, Neurologists. I have been tested for every imaginable thing, all come back clear!!! 'You're a mystery woman,' they say!!! I have questioned Prolia, 'doesn't do that,' they say... 'keep having it for your bone's sake,' they say!!! Well, I'm done with it. I'm miserable, can hardly walk. Everything hurts, bed is a nightmare. Can't do anything without groaning, life sucks!! I can't believe that no one listens to us, the users... aren't we the real voice of how this drug is affecting us?"

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  • Anonymous
  • August 24, 2023

"Had my second shot on July 13, 2023. Then on July 27, I broke my rib. I've never broken a bone in my whole entire life. I am 67 years old now. My whole body is aching. My fingers, wrists, and arms hurt. My jaw hurts. My back is in tremendous pain constantly. I feel like my whole bones are breaking inside. I can't sleep. I won't take this again. It really saddens me that they give this to people."

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  • Bone...
  • April 27, 2023

"My first injection of Prolia was in April of 2022. Six (6) hours after the injection a mass started growing on top of my left foot, within days I had severe pain in my left thigh, my left ankle was extremely painful, my teeth felt terrible and two of my lower front teeth chipped. When I went to the dentist to have my teeth examined and cleaned, I did not tell them I had taken Prolia. I was scared they would not see me. My left foot would not flex normally when I walked or tried to swim. I knew I would not take another injection. A year after the injection I developed a large bone cyst/tumor in my left foot. Amgen's new drug being advertised for bones in Evenity is twice the cost of Prolia. The recommended dosage of Prolia is two injections a year at the cost of $2,400.00. Evenity is two injections for $4,80.00. Amgen is making a fortune selling this poison. Please do not take these dangerous drugs. Taking Prolia was one of the biggest mistakes I have ever made."

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  • nana
  • Taken for less than 1 month
  • May 6, 2021

"I had my 1st Prolia shot 2 weeks ago. 24 hours after injection, I got a severe headache which I still have. I am having bone and joint pain to the point I have to take prescription pain meds to even function. Previously, I had taken a Reclast infusion; I almost died from side effects. So, my doctor put me on Fosamax. I had no reaction to Fosamax, but my bone scan showed only minimal improvement. That's when my doctor suggested Prolia. I should have refused and stayed on Fosamax, but unfortunately I didn't."

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  • Smurf...
  • January 5, 2020

"I took my 1st & last Prolia shot in Nov. 2019. Immediately, my mouth and tongue went numb and has continued to happen off and on. Severe headaches, the worst jaw and ear pain ever. I’ve also had 2 different cases of MRSA in my right ear. My leg muscles feel locked up at times, making it hard to walk, and sometimes causes me to lose balance. I have constant bone and muscle pain in my neck, shoulders, back, ribs, and abdomen. I itch so bad at times I scratch constantly. Severe constipation. Bouts of vomiting that come out of nowhere. Fever and chills. I’m sure I’m leaving other side effects out. I was already living with chronic pain daily basis, this shot has caused my pain level to skyrocket and become constant. I hope the side effects will subside soon and go away completely at some point. My GP asked me to at least try one shot. In 2018, I fractured my back at the L-2; Oct. ‘19, another fracture at the T-8. I would strongly advise you to not take it, based on my experience."

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  • PAMELA...
  • Taken for 2 to 5 years
  • August 16, 2019

"My first shot of Prolia in 2017 was ok, then after the second shot the side effects broke loose. Now 2 and a half years later (I stopped taking it of course) I still have a screwed up bowel system, bad IBS (irritable bowel syndrome), lots of small fractures, my life is ruined by this awful medicine. Don't take Prolia no matter what!"

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  • Kaydee
  • September 12, 2019

"My main experience with this drug is having doctors and nurse practitioners practically force me to take it, through fear tactics and intense pressure. I tried the once-a-year Reclast infusion, but got bad vertigo and nausea, so they switched me to Prolia. I read reviews and was so scared that I decided to never take it again and skipped about a year. My rheumatologist met with me and convinced me to take it again because my bones were so bad. After the second shot, I developed a UTI, but the ensuing bone density scan was encouraging. My third shot was on April 3, 2019, and on April 4, 2019, I woke up with severe vertigo, and landed in the ER. The doctor said it was just a coincidence. I told the doctor I'm not taking it again. We have an appointment next week, as he says we need to discuss a plan, as getting off this can cause fractures in the spine. This sounds like a no-win situation... not sure what to do now, and I have no one I can trust for good advice!"

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  • Lizzy...
  • September 3, 2014

"Received the first shot at the end of June. Within a week, I started with a rash on my neck. It was red, swollen, and itched day and night. Second week started with red blotches on either side of my mouth. They blistered and peeled, and were painful and itchy. It is now over 2 months later, and the redness is fading, but the itching is still awful, waking me up at night. I have tried everything with no relief. I will not be taking another shot."

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  • Sandy
  • Taken for less than 1 month
  • January 25, 2020

"I am two weeks in from my first injection of Prolia. I am experiencing fatigue and generalised muscle ache/pain. I would not have accepted this drug if I had prior knowledge about the vague knowledge available regarding the length of time side effects last! The side effect may or may not improve; they may get worse or even create more problems. I do not intend to continue this treatment where the benefits appear to be outweighed by the deficits. I was an energetic, vibrant person, now requiring paracetamol to keep moving and off the couch! And this might be permanent?"

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  • Mari
  • Taken for 1 to 6 months
  • April 19, 2023

"My doctor bullied me into taking the Prolia. I had taken Fosomax and had mouth and teeth problems. She said she could do nothing for me if I did not take it. Do doctors get a huge bonus for prescribing? The dentist said every patient he saw taking these bone drugs had problems, especially dental bone collapse. This is a nightmare."

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  • Patar...
  • June 30, 2019

"I was fine after the first shot of Prolia. However, after taking the second shot I almost immediately started experiencing side effects. Terrible pain in my hips, back, and legs. For some reason if I drive for more than 10 minutes, the pain becomes so severe that I have to pull over off the road and stand for a while. I told my doctor about these issues and how they began right after my second Prolia injection. She had an X-ray of my back and hips to look for fractures, but none were found. She said that Prolia builds bone! However, I have decided not to take another Prolia shot. In my opinion within 10 years there will be numerous lawsuits about this drug. Disgusting greedy pharmaceutical companies know about this drug!"

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  • Pood
  • October 28, 2015

"Prolia has the worst side effects of any medication on the market because it tampers with the immune system. I have had to call Amgen and the FDA numerous times for very serious side effects. This drug should be taken off of the market until medical doctors learn how to combat it. Once it's in, there is nothing they can do. In all reality, it is a chemo drug as its twin Xgeva just has more of the active ingredient in it."

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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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