Skip to main content

Bupropion for Anxiety User Reviews (Page 2)

Brand names: Wellbutrin XL, Wellbutrin SR, Aplenzin, Budeprion Forfivo XL Budeprion SR

Bupropion has an average rating of 6.0 out of 10 from a total of 173 reviews for the off-label treatment of Anxiety. 46% of reviewers reported a positive experience, while 29% reported a negative experience.

Reviews for Bupropion

  • Rod
  • Taken for 1 to 2 years
  • October 21, 2020

"Changed from sertraline to Wellbutrin, sertraline shut my libido down (can't believe she still loves me) and took me a while to figure that out (thanks Doc!) after a few months on Wellbutrin I have many of the same symptoms that I read here, insomnia is brutal, wake up at 4am to the sound of a neighbors car starting and I am up for good. Mood swings, anxiety worse then before... I can go on, blurry vision for sure.. Short tempered... none of which I had before WB. When I told my doc I wanted to stop she upped me to 300mg daily! I took her advise but I have had enough, this is crazy! It didn't work for me. With all these symptoms I forgot why I was even taking it. My original long standing issue was anxiety and OCD. I feel like I have spent most of my life trying to diagnose and find something to help me."

1 / 10
Was this helpful?YesNo
49 Report
  • Su K
  • August 11, 2015

"I have been struggling with Anxiety my whole life, the earliest memory I could think of involved some sort of anxiety. I've learned to cope with it as I got older but it seemed to always be one step ahead of me. I talked to my doctor and she put me on Welbutrin XL 150. As the years went on my anxiety increased due to stress at work, university and life in general. This caused me to develop depression to the point where I cannot watch a commercial without crying because the father said I love you to his daughter. I went to the doctor and she upped me to 300 and I was back to myself again. The medication has helped me cope through anxiety and depression! I am 25 F and using this medication for 8 years now"

9 / 10
Was this helpful?YesNo
94 Report
  • not...
  • Taken for 1 to 6 months
  • March 13, 2016

"Wellbrutrin at 150mg twice a day for is great. Some only need that same dosage in mgs once a day. In response to the medicine I have no racey thoughts. No depresssion, no side efffects as to sleepyines, zombified spells or attacks, no anxiety, no boredom, no crying and or laughing spells. THIS MED at 150mg is a blessing from God."

10 / 10
Was this helpful?YesNo
87 Report

Frequently asked questions

  • Crystle
  • October 17, 2012

"I was on Bupropion XL. I had to up my dose after 6 weeks of not feeling any different. I would get anxious over nothing at all and it was really depressing me because I couldn't control my emotions. I would get angry over little things that shouldn't even matter and have no patience. Now that my Dr. has changed my dose, I feel 10x better. It took about 8 weeks to actually work but it was worth the wait. I laugh more often and am just happy in general. It's not like most medicines where you feel loopy or... it's a subtle change that has big effects. I take my time now and am not so anxious about everyday things. The only reason I gave it an 8 out of 10 was because it took so long to work."

8 / 10
Was this helpful?YesNo
111 Report
  • Danie...
  • Taken for less than 1 month
  • March 9, 2018

"I was prescribed Wellbutrin a week ago for anxiety. Saw marked decrease in anxiety within 3 days. Side effects include weight loss (6 pounds this first week!) and I feel the need to go to bed earlier than usual (works for me!). Have had no negative effects yet."

Was this helpful?YesNo
67 Report

Are you taking this medicine?

  • organic...
  • July 8, 2017

"Just started this at 300MG a day 2 days ago and I literally feel a big and positive difference in my anxiety. I have PTSD from a violent event and have had pretty severe panic attacks for the past 3 years. I haven't been on any anti-depressants before but drink wine every night to relax and sometimes feel very agoraphobic. I know it's only day 2, but I just feel lighter, whenever I think of things that normally trigger me the thought comes and then just fades away. Honestly, I've never been a big believer in medication for mental issues but am really rethinking it now. Also vivid dreams, but they were good. Decreased appetite, a little more energy. Good luck everyone!"

8 / 10
Was this helpful?YesNo
67 Report
  • Jman
  • October 30, 2014

"So first off I have generalized anxiety, panic attacks, worry 24/7 etc. At first my doctor prescribed me Lexapro and worked great for 2 months and then started getting depression, and all my symptoms again. Also all I wanted to do was sleep then sleep some more and so on. So my doc switched me to bupropion HCL ER XL 300mg and only took two days to start feeling the effects, from the switch. I feel better already, can actually focus and get out of my head, have energy, feel great, and have interest in hobbies I once had. Felt very little anxiety today but so far I feel like I'm getting my life back! Also take Buspar but only started taking it a few days ago so hopefully all goes well!"

9 / 10
Was this helpful?YesNo
83 Report
  • Zack
  • Taken for 1 to 6 months
  • September 23, 2018

"I've been taking Wellbutrin XL 150mg for almost two months now. It was fantastic for my depression and anxiety for over a month and a half. Up until recently when my panic attacks have returned. Going to have my dosage raised, however; with the less side affects as of many other antidepressants, Wellbutrin overall has been a life saver. From someone who would have panic attacks sitting in the middle of 5 oclock traffic, to someone who can now kick back and listen to the music with my car windows down. Don't be afraid to try it! Also, this may NOT be the meds for you, but that's okay... I went through Celexa and Paxil before I even got to this. Hope you find some relief!"

6 / 10
Was this helpful?YesNo
56 Report
  • Getme...
  • January 4, 2013

"I have been suffering from depression and anxiety for years. That last year my anxiety has reached the point of almost constant panic. It is affecting every aspect of my life, and worst of all my confidence in doing my job. I have been desperately seeking some relief. I have had ruminating thoughts, fear of death/failure, overall guilt, etc. Anyways, I have been on the medication for 10 days. The first 6 were wonderful. I actually got out of bed and played with my kids! However the last four days the an anxiety is creeping back. Doc just upped my dose to 150 from the 100 (SR generic). Hopefully this will work out because I've tried SSRI's and SSNRI's and they make me feel like I'm going to flip out. Complete worsening of depression and anxiety."

10 / 10
Was this helpful?YesNo
90 Report
  • Anonymous
  • May 22, 2015

"As a college student, I felt like I needed some support to get me through difficult times that I couldn't do myself for a number of reasons. I tried meditation and relaxation but to no prevail. My twin has been on Lexapro for years now, so I went to my PCP to try Lexapro. It was not helpful at all - it made me want to chain smoke, when I drank it was not a pretty combo, and I was constantly tired. When I got on Wellbutrin starting out at 150mg, it's like I finally saw the light. Everything has just been so much better! I can concentrate better, I'm almost always in a good mood, and I haven't had any huge issues with anxiety. Now I've been on 300mg for almost a month, so we'll see how this goes!"

9 / 10
Was this helpful?YesNo
74 Report
  • JennyT
  • October 15, 2014

"I was on Lexapro for about 6 months before my doctor switched me to Wellbutrin due to weight gain and sexual side effects. I experienced intense headaches for the first few days, and dry mouth for the first 2 weeks. Both have since gone away. I have also lost 11 pounds in one month, which brings me just below my pre-Lexapro weight. I would attribute much of this to the reduction in appetite I have experienced with wellbutrin, as well as increased metabolism. My anxiety is under control and I feel great!"

9 / 10
Was this helpful?YesNo
76 Report
  • KMano
  • Taken for less than 1 month
  • February 26, 2020

"Over the past 2 years, I have had really bad anxiety. Nervous, sweaty, dizziness, lightheadedness, and a little bit of shortness of breath. This bupropion was the first antidepressant I have ever tried and I don't like it. However, I have to friends who are on it and are doing really well who suffer from BOTH anxiety + depression. I only have anxiety so I'm not sure if this is the right pill for me. It did help me lose weight, and helped my breathing, but it made me very emotional, I would cry for no reason. I took it for 12 days and decided to stop. Best of luck to you, I'm going to try buspar just for my anxiety and if I don't like this I'm going to try Zoloft."

4 / 10
Was this helpful?YesNo
41 Report
  • Ninja...
  • May 13, 2016

"Female, 26, suffer from anxiety, depression fatigue, sexual dysfunction due to heart surgery, hysterectomy, and traumatic couple of years. This stuff helps so much! I have energy and able to have conversations with strangers and enjoy a social life and after over a year of a complete lack of sexual interest and problems, I finally have a labido again! Not that I needed to lose weight but I was 133 lbs and due to thyroid trouble was unable to get back to my 120 lbs until starting this medication."

9 / 10
Was this helpful?YesNo
66 Report
  • R0x4nn3
  • January 13, 2017

"I took this medication for anxiety, bc it was recommended by my doctor and therapist. I also read some reviews of how well it did for others. However, I didnt have a good experience at all. I only took the medicine for 3 days, and my anxiety increased exponentially. The 1st day I experienced migraines, dizziness, increased heartrate, ringing in ears, and nearly all other side effects. The second day I felt frantic and wanted to crawl on the walls. I also woke from panic and fear in the middle of the night. On day 3, I woke up angry like the Hulk, violent like. The side effects continued to get worse through the morning- flashes of heat, dizziness, further increased heart rate, panicked feelings, on & on. I DO NOT suggest this for those w/ anxiety"

1 / 10
Was this helpful?YesNo
60 Report
  • Poppy
  • March 9, 2015

"I've been on Seroquel for 4 years on 300mg. Everyday I woke up like a zombie had no energy. Everything has dark and gloomy, plus I had no energy whatsoever. I researched Bupropion I'm on 150mg only once a day. I'm still coming off Seroquel from 300/150/50mg. Since taking Bupropion I have so much more energy everything seems brighter. I seem more interested in simple things, more organized. I actually notice myself laughing at little things, I feel like I forgot to laugh so it was a strange feeling when I was. I'm still a bit groggy coming off the Seroquel but hopefully this will work for me."

8 / 10
Was this helpful?YesNo
67 Report
  • Review
  • Taken for 1 to 6 months
  • April 9, 2016

"Was on lexapro for maybe 3 years for panic attacks and anxiety. That made me kinda numb. Not really any sex drive, I used to sweat at night with lexapro, it helped with PA & A, but gained weight, and raised cholesterol levels dramatically! I asked to start welbutritin to quit smoking and slowly tapered off lexapro. I'm now taking .5 lexapro maybe 2 times a week till brain zaps disappear..... Now on to the welbutritin... 3 months of Xl 150 a day in the morning, I lost ten pounds! Feel amazing.... And the sex drive is Wonderful. Until I started Wellbutrin I didn't realize how much lexapro affected that because, you just don't think about it, that's part of the numbing I guess. I'm very happy that I switched!"

10 / 10
Was this helpful?YesNo
60 Report
  • Cano
  • Taken for 1 to 6 months
  • October 28, 2019

"On week 6 of taking 150mg bupropion per day to treat the feeling of taking on too much (anxiety). No depression, nor history of depression. Last night, I was driving with my kids in the car and had a major panic attack. I have never in my life had this sort of attack. It was completely debilitating and I had to pull off the road and into a parking lot. I was crying uncontrollably, shaking and had no idea what was going on. My oldest son called for help and we got home safely. I stopped taking this drug this morning and will likely never take another antidepressant again."

1 / 10
Was this helpful?YesNo
38 Report
  • am1020
  • Taken for less than 1 month
  • December 16, 2017

"I have tried many anti-anxiety medications and each one always seemed to have a side effect. The main side effect was loss of libido. So with that being said I went off anti-anxiety medications completely. Until the past month, I was have panic attacks, tightened chest, depression. I went to my doctor and explained how all the anti-anxiety medications caused loss of libido. So he put me on this medication and it has been a life saver. No more panic attacks, I feel happy and content. Plus libido is back! 100% Recommended."

10 / 10
Was this helpful?YesNo
46 Report
  • Anne...
  • Taken for 1 to 6 months
  • December 25, 2019

"I have been on Bupropion for only 6 -7 weeks. At first 150 XL then 2 - 150 XL after a week. I had to drop back to one tablet after the second week because I felt too wired and couldn't sleep. The day after dropping back the dose I was very tired and sleepy. Finally a week later I went back to 2 - 150XL and its going better so far. My anxiety is definitely lower as is my blood pressure. When first starting the medication I felt more sexual. This has happened before on SSRIs as I recall. With just the Bupropion now, I seem to have atomic orgasms. I also have more alertness, very much improved memory and much less dyslexia. I am not sure if my erections are somewhat more difficult, definitely amazing orgasms."

Was this helpful?YesNo
34 Report
  • MsTexx
  • September 15, 2011

Wellbutrin (bupropion) "After trying several from the Prozac family, with really bad results, I was given Wellbutrin - what a live saver! It completely smoothed out the rough edges so I could feel normal, not anxious and irritable all the time."

10 / 10
Was this helpful?YesNo
74 Report
  • She...
  • August 5, 2015

"Diagnosed with Social Anxiety Disorder & GAD, I started taking this medication at 150mg. After 4-5 weeks of dry mouth, headaches, night sweats, abnormal dreams, and a slight head jerk every now and then, my anxiety had almost disappeared. I lost 10 lbs the first 2 months but eventually gained it back which I didn't mind. WB has made a huge difference with the physiological symptoms of my anxiety, meaning that I no longer feel physically uncomfortable, especially in social situations. My doc has increased my dosage to 300mg after being on 150mg for 8 months. So far after one week on the new dosage, all the initial side effects I had when I first started taking WB have returned, but with the addition of dry eyes & blurred vision."

9 / 10
Was this helpful?YesNo
56 Report
  • somep...
  • July 17, 2018

"I was prescribed this for my depression and generalized anxiety after zoloft (sertraline) failed me. At first definitely had a hard time adjusting to the energy spike and having a harder time falling asleep. After about a month those went away completely and my depression was workable and similarly with the generalized anxiety overall. However I do have certain side affects such as decreased appetite, I can still eat I just don't realize that I haven't gone awhile without eating on some days, once I became aware of that it wasn't a problem (expected to an extent as this is apparently also prescribed for weight loss?) I have developed a generally more sensitive stomach however not to the point of impeding my life or outweighing the benefits. Sometimes I do feel like I have too much energy or more than I should for whatever situation I'm in, which can lead to a panicky feeling similar to a borderline anxiety attack, but just being aware made the difference in controlling it."

9 / 10
Was this helpful?YesNo
41 Report
  • SlimTee
  • November 10, 2013

"I started this medication at 150 mg xl about a week ago... I feel slightly different. ... I had a panic attack at work the other day.... which scared me.... I dont get as upset as before. My sex life is great! I think Im going to give it another week and maybe increase my dosage..."

6 / 10
Was this helpful?YesNo
61 Report
  • Emma
  • Taken for 1 to 6 months
  • October 14, 2019

"I absolutely hate this drug. Within the past year I have been experiencing the worst anxiety and panic attacks I’ve ever had. I went on lexapro which seemed to calm my panic and my anxiety in general. However, I thought I started to gain some weight and I thought it was the cause so I asked my doctor to switch me to something else. She switched me to bupropion. At first it was fine, but now it’s about my 5th week on it and if I thought my anxiety has been bad this past year it’s NOTHING compared to how I feel now. Pure panic when doing the most mundane tasks and my brain is racing with anxiety and scary thoughts. I went on this drug for anxiety and it has made my anxiety 100 times worse and has even begun to cause depression which I wasn’t struggling with before. I would absolutely rather deal with the weight gain of lexapro then this horrific drug."

1 / 10
Was this helpful?YesNo
33 Report
  • Crys
  • Taken for less than 1 month
  • November 27, 2019

"So, today is day 3 for me. I’m a lot more awake. I was prescribed this bupropion to take with Lexapro. It started slowly, and if I’m not focused in on something, I realize how anxious(energized) I am. I have a busy schedule, and have had problems getting out of bed before this. Nothing too serious, just took more effort than most. To have this extra boost is different. I have had crying spells at times, nothing I couldn’t control though. I little more sensitive to negativity. But, like I said, it’s only day 3. Really trying not to get discouraged with all these negative reviews."

4 / 10
Was this helpful?YesNo
32 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Anxiety

Care guides

Medicine.com guides (external)