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Saphris User Reviews & Ratings (Page 3)

Saphris has an average rating of 7.3 out of 10 from a total of 272 reviews on Drugs.com. 69% of reviewers reported a positive experience, while 18% reported a negative experience.

Reviews for Saphris

  • Any...
  • Taken for 1 to 6 months
  • November 8, 2015

For Bipolar Disorder "I have been on various antidepressants since i was 18, with some relief at times. I've been very functional all along but never happy. I've used other illicit substances to self medicate. I saw a psychiatrist when I finally got sick and tired of spinning my wheels. She diagnosed me with bipolar 2 and put me on saphris. For the first month, I felt AMAZING. I was getting things done at home, at work, and even nurturing a social life again. The med still works weekly for my mood but I've gained 20 lbs in just 2months. This is really starting to get me down. The med had changed my life, but I'm not sure how much longer I can deal with the weight gain. If it weren't for the weight, I would've given it a10."

8 / 10
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  • Mrspi...
  • Taken for 1 to 6 months
  • March 26, 2016

For Bipolar Disorder "Started on Saphris 2 months ago for sleep and bi-polar. I started at 5 mg---total nightmare! Couldn't sleep, picked arguments with my husband and was generally very hyped and energetic ( in a good but bad way!). I never saw a manic episode coming at me--but I saw this one! After 5 days I called the doctor and was advised to go up to 10mg. WOW!! Immediate turn around that night (I only take it at night) and my sleep was fantastic! My attitude was amazing and my husband was delighted with his loving and easy going wife! I felt great--not drugged just happy and content. Work with it--it's turned my life around!"

10 / 10
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  • Negat...
  • Taken for 10 years or more
  • March 10, 2022

For Bipolar Disorder "This drug ruined my life.I started taking it when I was 9 years old until I was 17. I gained 30 pounds. It made me so tired to the point I couldn’t wake up In the morning. I would miss school and sleep till 2 PM.My parents tried to wake me, and I would start throwing up every day if I woke up before 12 in the afternoon or pass out. It was nearly impossible to wake up. Keep in mind-I went to bed at 8 pm daily. I missed out on a lot of my life and failed high school because I couldn’t wake up. Which made me unable go to college. I would wake up drenched in sweat. I would get extreme stomach problems. I got nightmares so bad I woke up screaming. It made me socially awkward, and I slurred my words on it and started to forget how to speak. I had to go to a speech therapist. My parents forced me to take it. I secretly stopped taking both at 17 ,Although I feel it has changed my Brain permanently not for the better & long term health issues. My life became better as soon as I got off it and happier."

1 / 10
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  • Anonymous
  • April 24, 2012

For Post Traumatic Stress Disorder "I have had depression and anxiety panic disorder, suicidal thoughts and post traumatic stress disorder for about 25 years. I've tried pretty much every medicine you can think of for these conditions. When I started on Saphris I started feeling better after the fourth day. I actually felt a little manic because I was cleaning my house like a normal person. I thought this could be it. Finally. It has been a miracle for me, I have nothing negative to say about this medicine it's wonderful. "

9 / 10
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  • Anony...
  • December 20, 2013

For Bipolar Disorder "I have Bipolar Disorder I, with rapid cycling and mixed states. I tried Saphris when I was recovering from a hospitalization which was very unpleasant and ended very badly. So I was a bit manic and terribly anxious going on it. I took it for 6 days. It seemed to work almost right away. I was shakey and anxious throughout the 6 days. Extremely sleepy and dizzy after my 5mg at bedtime. But that wore off after 4 days. Mood-wise, it seemed to completely stall my cycling. Miracle! And I was much calmer and less reactive, but definitely awake during the days. Then after my 6th dose I noticed my lips were puffy, and my tongue was fatter, then my throat got tight = allergic reaction. Worked great until that!"

9 / 10
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Are you taking this medicine?

  • Kite
  • October 14, 2016

For Schizophrenia "Hi! I have been on this medicine for only 2 weeks and I already know that its the best thing that could happen for me. I wanted to post so others know that the benefits of Saphris are real in my case. Perhaps peoples side effects are from other medicines/withdrawal from other medicines??... I was on olanzapine but I continued to have unclear thinking and my weight gain over a year was astronomical. I live in Australia and its a subsidised medicine here, it is truely the lucky country and Im so very greatful, this medicine is changing my life."

10 / 10
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37 Report
  • needy...
  • Taken for less than 1 month
  • July 31, 2019

For Bipolar Disorder "First night I took it, sent me into a psychedelic dream. it was like a full psychedelic trip. I went into the 4th dimension and was communicating with my past/present/future self all at once. I was everything and everyone. I was matter. energy. I was the universe. Before this drug, I never dreamt. I slept like a baby, but Saphris completely changed that.I was in full blown insanity, and on and off psychosis for days after the trip. In my mind, we are all one. so death is nothing. I am everything anyway, this shell of a body I use is not me. waking up felt like I had just come out of a coma, I had no idea who I was, where I was, and how long had passed. one second in our time felt like millions of millions of years in my dreams. I took it for another 3 days, then stopped. to this day the nightmares have never left. Some nights are worse then other. From just this one 'dream', whatever was in that drug changed something in my brain forever."

1 / 10
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26 Report
  • Anonymous
  • October 23, 2011

For Schizophrenia "For the first few weeks, I felt amazing. So much better, I couldn't believe it. I hadn't been that totally free from visions with any other medication. I didn't much enjoy randomly falling asleep when I took my afternoon dose, but at the time it seemed worth it. However, after about a month, I started feeling like the best thing for me to do would be to kill myself. I didn't get depressed, none of my old symptoms returned, I just felt like it was the logical thing to do. It felt so normal that I didn't report it to my doctor for a month. He told me to stop taking Saphris and within 2 weeks all of my suicidal thoughts stopped. My symptoms returned, but it was a fair trade. I just want people to know and to be careful."

3 / 10
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53 Report
  • Jessie
  • September 13, 2017

For Bipolar Disorder "After 15 years of trying different meds, this is the first one to give me a positive change. I used to be suicidal everyday & had a hard time leaving the house. Everything was overwhelming. Since starting Saphris my mind finally feels like it has "brakes" and my thoughts feel lighter. I'm feeling true happiness, even happy to wake up. Little to no side effects 3 months in. I take it at night because it does make me sleepy. Sugar cravings I've noticed but an trying to control that because honestly this med is giving me my life back. Cons: 20 minutes of a nasty taste in your mouth because you dissolve it under your tongue. Sugar/carb cravings but no excess weight gain yet."

9 / 10
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33 Report
  • Tater...
  • Taken for 5 to 10 years
  • March 3, 2020

For Bipolar Disorder "I've been on saphris for about 6 years or more, in my personal experience I believe I have been exceptionally well, when I miss a few days I realize how off I become but go back to normal while I'm on this medication. I think doctors should familiarize themselves with this medication more because I think it would be great for others that suffer with bi-polar disorder"

10 / 10
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23 Report
  • Lovaj...
  • Taken for 1 to 6 months
  • September 14, 2016

For Bipolar Disorder "I had tried many medications to level out my bipolar disorder and relieve my GAD and it seemed that when I would get one symptom straight one of the others would reappear. Years it took, eventually my doc decided to try something new when the depression hit and nothing seemed to be helping. So I started trileptal, which helped noticeably but I wasn't sleeping so he recommended saphris to help me sleep, I was a little apprehensive but desired to feel better so I agreed to try it. I am beyond satisfied with it. I feel better than I have been in as long as I remember. I am back in school full time and working full time without the edginess if mania. I feel like myself again. My friends and family have commented on how well I seem to be."

8 / 10
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  • Heidi...
  • February 18, 2016

For Bipolar Disorder "I took Saphris and was given 10 mg samples from my Dr. I felt great! After a few weeks of samples- I went to fill my prescription.....After insurance it was $400.00! I couldn't afford to get it filled. It really stinks that a medication that made such a difference for mental health could be so costly. I can only imagine this is why so many go without medication for mental illness."

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  • Life...
  • Taken for 6 months to 1 year
  • April 9, 2014

For Bipolar Disorder "I started out with 20 mg of Saphris but stayed groggy. Went down to 10 mg and have been on it for 6 months. I also take a sleep aid at night and now I sleep 6-7 hrs compared to 3-4. No running thoughts in my head. The longest time I have ever stayed out of the hospital in 12 years. I feel wonderful, when I start getting anxious, I take a 5 mg with my Xanax and I am good to go. Downside: Gained 50 pds and cholesterol is through the roof, even though I do not eat red meat. Always have the munchies though. Had to start on a statin medicine. Blood sugar is higher than usual but within range. Keeping an eye out on this too. But this is the only medicine that has worked for me without being a zombie or continued mixed episodes."

9 / 10
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44 Report
  • djeck
  • Taken for 6 months to 1 year
  • June 29, 2014

For Bipolar Disorder "Bipolar with mixed episodes, ADHD and severe anxiety. Saphris was a miracle for me also. I've been on disability for 10 years and this is the first medicine I've taken that has made me functional. Absolutely can't take it the morning; it makes me incoherent for about 3 hours and I eat everything in sight. So I take all 20 mgs at night and am doing fine. Have mouth sores, though. My doctor said to alternate between taking it sublingually, supra lingually and but ally and it's helping. "

9 / 10
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  • KristiR
  • Taken for 6 months to 1 year
  • August 17, 2013

For Bipolar Disorder "I am currently taking 1/4 of a 5 mg tablet (but started out on a 1/2 tablet) of Saphris at night. I am also on Lexapro, 10 mg for depression and anxiety. The combo works great. I have horrible insomnia/waking in the night on just Lexapro (or other SSRI's I've tried) but with Saphris I sleep great and wake up refreshed! Only downside is that I've put on 10-15 pounds in the last 6 months, but not sure if it is due to the Lexapro or Saphris or both. I eat very healthy (just too much) and exercise regularly....but find myself always feeling hungry. Oh well...at least I'm happy!"

9 / 10
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46 Report
  • Grann...
  • Taken for 1 to 6 months
  • March 10, 2013

For Post Traumatic Stress Disorder "I have been on Saphris for about 5 weeks. I started at a low dose, 5mg at bedtime and just increased to 10mg a couple days ago. I love this medicine! I sleep at night and wake up feeling good in the morning, I haven't experienced that in YEARS! My PTSD episodes have greatly decreased in intensity, duration and how often they occur. I really do feel like a new woman!"

10 / 10
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  • Boxer...
  • Taken for less than 1 month
  • October 25, 2012

For Bipolar Disorder "I have been taking Saphris for 10 days. I went cold turkey off Seroquel 600mg/day. I have had terrible insomnia. My psych said this should improve over next few weeks, I hope so. Agreed that it tastes awful and numbness under tongue only lasts approx half an hour. My mood improved the next day after my first 5mg dose. I feel so happy and enthusiastic about life, which is amazing. The Seroquel fog has lifted and I have lost 3.5kgs in 7 days (Seroquel munchies are gone)."

9 / 10
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48 Report
  • Kenis
  • Taken for less than 1 month
  • December 18, 2015

For Bipolar Disorder "I have been on Saphris now for 1 month. I have not been this happy in 35 years! I am working out ever day now at the local health club. Last night I swam for over 40 minutes straight. The only side-effect of this med is excellent REM sleep and a good night's rest. Heaven help you if you don't have insurance....Very Pricey $$$$$"

10 / 10
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  • kenboy
  • Taken for 1 to 6 months
  • February 25, 2018

For Bipolar Disorder "I don't know what the big deal is about the taste---I have the cherry and yeah, its not great, but if you want to feel better than you have to deal with it-----feeling better is all worth it to me...has helped me greatly------do not be afraid to try it---"

10 / 10
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30 Report
  • johne...
  • February 22, 2010

For Bipolar Disorder "Dissolves very quickly compared to other sub-lingual tablets that I have taken - tastes horrible though! I have experienced no negative side effects, and it has definitely elevated my mood and taken away the "shadows" and some of the "noises" that accompany my diagnosis....overall seems to be much better than the last two meds I was prescribed (Lamictal and Abilify). I give it a ten!"

10 / 10
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55 Report
  • ELaet...
  • July 30, 2017

For Schizophrenia "Saphris has done wonders for me. I have been on 10mg at night since July 7th and I have lost 4lbs already. I was on Invega paliperidone 9mg for 10 years. No matter how hard I tried (fasting, counting my calories) I couldn't lose weight. I like how Saphris puts me to sleep right away but I'm not tired the next day.Also, I have my sex drive back which I never had on Invega. I am so glad they have come up with better medications these days."

10 / 10
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31 Report
  • Tonya...
  • March 31, 2012

For Bipolar Disorder "I am bipolar and I was not on a mood stabilizer, due to severe sensitivity to side effects. I take Klonopin 1 mg and Lamictal 150mg twice a day. I was taking Ambien for sleep, but now with the Saphris, I don't need any sleep medicines and I am so much more relaxed and not stressed out. I'm very happy that I've finally found something that is working. My mind has slowed down, deeper sleep modes and less stress reactions to people. I feel great. Not manic great, just great. I'm thankful to my family for their support and standing by me in the rough times of the disease. My family is benefiting as well. I have to rate this as a 10. The taste is bad, but the cherry is helping. Much luck to all to try and see if it can help you too!"

10 / 10
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47 Report
  • Anonymous
  • March 19, 2012

For Bipolar Disorder "I have struggled with bipolar disorder for twenty-some years and never been stable. I've tried most of the atypicals and all the mood stabilizers. After Saphris, I am stable for the first time in my life. The shadows, delusions, mania, depression, anxiety and sleep problems are all gone. I take the black cherry as I cannot tolerate the original, but the taste is worth it in how well it works. Two weeks after starting it it was like someone turned the lights on. The world was literally brighter! I am back in school, working part time and happy and I didn't think it possible. I've been through 38 ECT treatments and every medicine without success before 20 mg Saphris. It's a miracle for me. I now take two medicines, down from 9!"

10 / 10
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  • Just...
  • Taken for 1 to 6 months
  • October 20, 2015

For Bipolar Disorder "I like saphris but have experienced the nasty side effect of weight gain. I had tried 4 other anti psychotics and all of them made me put on weight without relieving me of my bi polar symptoms. I am staying on saphris because for the first time I feel normal. No more high highs or low lows. However the increased appetite drives me nuts. I literally obsess about food all day. I recently cut out all processed sugar to see if this helps. If anyone has any advice I'd love to hear it."

7 / 10
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36 Report
  • HiSpR...
  • Taken for less than 1 month
  • February 7, 2015

For Bipolar Disorder "Diagnosed ADHD, Bipolar, Major Depression, GAD, Panic disorder. Have been on Saphris 5 mg at night for 1 week. After the first dose I could tell a huge difference in my mood. For the first time in months I woke up in a great mood. After a few days, I knew I was no longer in mania. Which I've been in for at least 4 mths. My thinking is back to normal. The only problem I'm having is keeping my mood stabilized. When I take it at night it puts me to sleep in 15 min. No longer using sleeping meds. For one week of use I think it's a great medicine."

9 / 10
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38 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.