Amitriptyline for Depression User Reviews (Page 4)

• Cera
• Taken for 1 to 6 months
• September 17, 2018

"I switched to this from clomipramine because I was having terrible side effects, unfortunately the amitriptyline is WORSE. My doctor tried taking me up to 150mg in hopes that it would break my depression, instead I've developed the worst acid reflux I could have imagined. At one point my entire throat was spasming all day. I can't get the rest I desperately need and it's making eating difficult and I'm already underweight. I've tried medications to get rid of it, but nothing is working, just making my stomach feel worse. I just pray that the reflux stops when I get off of it as it's driving me completely insane! I'm down to 50mg and go to 25mg tomorrow. I can't wait to get off this drug. It's literally not helped me at all, just made things worse than ever."

• Tinni...
• March 2, 2016

"Drug worked like a miracle on anxiety and depression - BUT, it made my ears ring and caused hearing loss. NOW more depressed than ever. 75 mg for 6 days and ear went numb. Nightmare scenario and I'm living it."

• Bright...
• February 29, 2016

"I used Tryptanol 20 years ago and found that this med worked for me. After trying so many other anti-depressant medications and I have found that I am always have to increase them, then they work for a while and then I have to increase the meds again. I recently went on Endep and I could notice a difference in a few days. I chose to go back on these meds. It wasn't the Dr's suggestion. I'm so glad I went back on these :) The only side effects I have noticed is a dry mouth."

• Alano
• Taken for 1 to 6 months
• October 6, 2019

"I’ve been on 30mg amitriptyline for 6 months it works well with treating my depression and helps me sleeps, but I’ve put weight on and feel confused often. I’m reducing it and thinking of it replacing it with healthy eating and exercise ."

• Pattie
• March 15, 2018

Endep (amitriptyline) "I dropped 50mg of Endep cold turkey over 3 years ago. I ended up with 24/7 migraines for a month, collapsed and was taken to Hospital and unfortunately the Doctor started me back on Endep He said they were good for Headaches. Left Hospital on a small dose and started having Panic Attacks all day every day, collapsed and was put back in Hospital. They increased my Dose of Endep. I am now trying to get off it again as it is not working, I am decreasing the Endep by 5mg a week."

• START...
• Taken for 2 to 5 years
• May 11, 2022

"Why don't they start "cocktails" with Elavil? Over the last 10-15 years (of misdiagnosed "anxiety" when really I had Graves Disease), only Ativan or Xanax helped. Yes, I still take Xanax, but no SSRI had helped at all (severe reactions to those, probably due to my hyperthyroidism, but one SSRI pill would land me in the ER); I went through the laundry list of stupid "tricyclics" (Remeron, which was okay for 25 days, then my usual easy-going self got enraged for no reason, so my doc pulled me off that: I'm not an 'angry person'; trazadone). After I got my thyroid diagnosed, I still had panic attacks and needed Xanax, but the doc said he had to put me on something else. I expected a failure, but said I'd "heard of" Elavil and could I try it. It's been a few years now, I take 25mg/night, knocks me out but not "hard" (I get good sleep), and I feel like "me" again. START with this one! It's GREAT!"

• Stephen
• Taken for 10 years or more
• March 20, 2019

"I suffered from headaches for 40 years until I started to get depression after some horrible life events. It did help with the headaches and does help with the depression, but I do have bad days which may last for 3-4 days. I take 125mg which I am told is a lot. I do get side effects. I have been on it for 12 years. I am going to ask if there is a better alternative."

• Carlo
• Taken for less than 1 month
• February 16, 2019

"Good information. My daughter was started on Amitriptyline 25gm for depression treatment. On day 5 we tried increasing dose to 50mg which immediately induced train of unwanted thoughts with compulsive reactions-obsessive compulsive disorder(OCD). We dropped dose to 25mg but OCD persisted. We withdrew Amitriptyline on day 10 and started Prozac 10mg. OCD with unwanted thoughts improved immediately and stopped 3 days later. Concluding, amitryptyline improved depression but induced OCD."

• mame
• May 24, 2018

"Experience is the best teacher, my journey with amitriptyline started last year. I was sick for a very long time with no single day of relieve, antibiotics and antimalarials with no result.From the area I come from people will term this unresolved issue spiritual.I went from church to churches still no result until I went for a proper medical check up when all test results came out negative. I was prescbed amitriptyline December 2016 and this drug happened to be a life saver. I increased the dose from 25mg till as high as 125mg, at this point I felt very good with myself, my life was blissful. After sometime my doc started to help me taper off it. I gradually tapered off the same way I increased using it. All was fine all the way I stopped using endep the last week of last month. Right now I'm in the depression stage. I am using 50mg but still no improvement. I sleep but wake up at intervals. Will increasing it help?? This drug has really worked for me."

• user10k
• May 8, 2021

"Been suffering from depression and anxiety for over 10 years. This medication did nothing to alleviate my symptoms. I've been taking it for almost 3 weeks now, yet I'm exhausted, lethargic, I feel spaced out most of the time, I force myself to do things that I absolutely must do but I don't do a good job because I really don't want to do them. I'm going back to my Dr's office to see if my dose could be increased or I could go on a different antidepressant. I've tried SSRIs in the past, and while they had their own problems, they seemed to work instantly for my mood. Giving it 3/10 because it does help me sleep at night and it didn't have any side effects unlike the SSRIs I was on before."

• S777
• Taken for less than 1 month
• January 2, 2023

"Since 2005 I suffered a long battle with Raynaud’s disease and severe depression. I have been hospitalized many times for both ailments. This medication took all my pain away and gave me clear thinking. I was taking Cymbalta which is horrible to wean off from and seemed to make me more agitated. Amitriptyline has made me feel normal again. Right now I’m taking 25mg at night but I may have to increase it to 50mg. I don’t know why or how it works but it does."

• mizu
• Taken for 1 to 6 months
• December 30, 2022

"I'm18 and was diagnosed with major depressive disorder and anxiety two years ago. I never thought I'd try medication for my depression, but I had gone to a doctor about my migraines and eye aches. They prescribed me with amitriptyline 10 mg, which happened to also be an antidepressant. I could easily pick it up from the pharmacy for $10 for 90 pills. I've been on it for more than a month and have noticed my feeling of sadness is much better, as well as a decrease in my impulsive thoughts. Plus my headaches are basically gone (except when I went off my meds for 5 days LOL). Don't feel like I'm gaining weight from this btw, but I do have an increased appetite, as I'd never feel happy enough to eat :) I would definitely recommend it!"

• blueb...
• Taken for 1 to 6 months
• July 30, 2021

"When I was 15 I was diagnosed with depression but being so young I refused to take medicine. This year has been the toughest year for me and I found myself in a really bad state of mind. My doctor prescribed me 10mg of Amitriptyline for my headaches and said it’ll help with depression too. I never felt the way I felt after taking this. The past 8 years I don’t think I ever went a day without telling myself “I’m so depressed.” I’ve only been on this medicine since May but it has made me feel better. Up until recently I started to feel down again for no reason. Maybe I need to up the dosage. Either way I’m so lucky to have started this medicine and have gotten no side effects. I truly felt like I was about to live a normal life for the past two months :)"

• Anonymous
• Taken for 1 to 6 months
• September 3, 2021

"Diagnosed with general anxiety disorder In March 2020. As is typical, I was on Lexapro for 7 weeks which made me feel worse. Switched to Effexor for 4 days and stopped as the side effects were unbearable so I totally come off antidepressants. I continue to be miserable and nauseous all the time. Finally I see gastroenterologist who diagnosed me with a functional GI disorder due to anxiety and prescribes Amitryptyline 10 mg and nausea is gone but my depression is still continuing as I have been dealing with this for months and although not nauseous all other symptoms exist. I slowly increase by 5 mg each week. The depression was awful but I persisted with the plan and by 30 mg the cloud began to finally lift. I’m at 35 mg now and I actually feel normal when I never thought I would ever feel normal again just a couple weeks earlier. Thank god for my gastroenterologist because my psych wouldn’t have even tried Amitryptyline. Thank God for this drug. It saved me."

• camsg...
• Taken for less than 1 month
• July 26, 2014

"I'm taking this more as a mood stabilizer. The medicine has caused my tongue to be sore, excessive dry lips, mouth and throat. It has help with my mood though. I can't take this medicine anymore. I'm contacting my doctor for some other medication."

• klshe...
• Taken for 1 to 6 months
• February 8, 2015

"I've had severe anxiety my whole life paired with depression and bipolar disorder. Ever since I was a child, I've had chronic migraines and headaches, especially at ages where I just shouldn't be having them. My doctor prescribed me this to calm me down and help stabilize my brain activity, so as to halt the anxiety and depression he thought was causing my headaches and migraines. The pill worked fine after the first few doses, but I guess my body developed a tolerance. Now, when I don't take it, I'm extremely nervous and my depressive tendencies skyrocket. My headaches and migraines never went away. I feel that this pull had a negative effect on me rather than actually helping, and I will be consulting my doctor for something else."

• Bunny
• Taken for 10 years or more
• July 18, 2021

"I was on Amitryptline for well over 25 years for various conditions including depression.I decided to slowly withdraw myself over 6 months. The most I ever took was 45mg nightly.THIS IS A WARNING TO EVERYONE: Make darn sure that you intend to stay on this drug because the withdrawal is horrendous. I have been off it for 8 weeks and it is pure nightmare material: insomnia, aches, bloating, panic attacks etc.I am struggling and wish I had never heard of this drug. I believe it is addicting. Yes,it helped me that is why I am warning users of this medication to be very careful because going off/staying off is the most nightmarish time you will ever have. Good luck."

• Anonymous
• Taken for 10 years or more
• January 13, 2022

"Amitriptyline 150MG once daily every night when he goes to bed is a life saver and helps him with his daily chronic depression disorder and daily chronic anxiety disorder. He takes it with his anxiety medication Busprione 10MG three times in the morning and afternoon and night and he gets the complete total daily protection with both medications everyday. They really help a lot and says goodbye to his daily depression and daily anxiety and if it wasn't for Amitriptyline and Busprione it would be really difficult to get through his days especially with this crazy COVID-19 coronavirus pandemic crisis this world has been going through 24/7 for nearly 2 years already. I think COVID-19 is going to be the daily normal thing that everyone is going to have face day to day for the rest of there life everyday and pray that this COVID-19 coronavirus pandemic crisis would go away for life and forever!!!"

• Molly
• Taken for 1 to 6 months
• October 20, 2018

"I was only on amitriptyline 25 mg for a few months and I started waking up with pain and stiffness in palms of my hands I don’t know if it’s from the medication but I stopped taking it and I’m waiting to see if the pain and stiffness goes away. Wondering if this has this happened to any one else?"

• Pk721
• Taken for 1 to 6 months
• November 12, 2015

"Not recommending this, on 25mg, knocked me out for 12 hours and groggy for the next 12 hours. Cut pill into quarters and still had strong effect causing groggyness all of next day. Went to trazadone, which is perfect for me."

• test...
• Taken for 1 to 6 months
• March 2, 2021

"Took zoloft (Sertraline) for social anxiety x 3 years. Feelings were too numbing, couldn't even cry when I wanted....not natural. Doc put me on 50mg of amitriptyline at first, but dose resulted in severe constipation. So reduced to 25 mg/bedtime, and stool softener, more water, fiber and workouts 2 or 3 day/ week. If your taking iron- may cause moderate constipation, be aware it could possibly make bowel movements difficult."

• owen
• April 4, 2021

"I'm really sad about probably having to need to stop this med as it has been absolutely brilliant for my depression & anxiety. Me = 47 year old male, long term depression/anxiety sufferer. I would always find that the common SSRI meds I tried in the past would ease my depression & anxiety, but not actually get rid of it fully enough so that I felt 'normal'. Then I tried amitriptyline (75mg a day) & for the first time in about 10 years, ALL depression/and anxiety, gone! Unfortunately I'm getting a side effect: 'tachycardia', which means this med is making my heart beat too fast. I was just sunbathing in the garden, totally relaxed, & even then my heart was beating way over 100 bpm. Note: a very common side effect which I get from amitriptyline, is dry mouth. This didn't actually bother me though, as it lessened as the weeks went on, plus I would just drink some water."

• D88
• Taken for 1 to 6 months
• March 1, 2023

"I took this for Seasonal affective disorder (SAD). I changed over from mirtazapine as I didn’t want weight gain. I’d rate it 8/10 for what it did for my mood, it lifted me out of hell within a week. Took between 10-30mg However, it had too many awful side effects so I stopped after 5 weeks. I experienced a faster heart rate and getting out of breath, chest pain, insomnia (I either could not sleep at all, woke every hour, or would sometimes wake with my brain feeling like it was fizzing), significant impact on my libido which also caused my vagina to go dry (resulting in painful sex and sores), some occasional emotional blunting and dry mouth. I also constantly bit my nails as it was so stimulating for me. Horrible withdrawal is still ongoing 5 days after stopping, I still have insomnia (even though I’ve started mirtazapine), and I have body aches and a headache. I’ve never had withdrawals from any medication in my life."

• dmgjgg
• Taken for 1 to 6 months
• July 7, 2022

"My depression/anxiety lasted almost a whole year, and I truly thought I was never going to feel better. Initially, my psychiatrist tried increasing Cymbalta (my medicine at the time) which only made me more anxious. I tried several different antidepressants, including Prozac, Wellbutrin, Clonodine, and Buspar before being put on Amitriptyline. Make sure you stay on Amitriptyline for 6 weeks before trying something else, because that is how long it took for me to feel myself again. I am also on secondary antidepressants Seroquel and Trintellix. Initially, I was put on 100mg of Amitriptyline, but I found that dosage actually increased my depression. My psychiatrist finally agreed to lower the dosage to 75 mg, which worked perfectly. It also helped my insomnia. I never thought I was going to get better and felt so hopeless. I was even ready to try ECT, but now I don’t need to. The only negative side effects are constipation and dry mouth."

• Anonymous
• Taken for 1 to 6 months
• January 20, 2018

"Was prescribed for bipolar depression. At first it helped with insomnia (& relieved constipation!) which was a godsend, but faded faded after a few weeks. After 1 month I had crippling fatigue & it seriously jacked my heart rate up, so lowered from 75 to 50mg. Spent another month developing akathisia before finally ditching it. I’m sure it’s great for some, but my body hated it. Not to mention it did squat for my mood."