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Amitriptyline for Depression User Reviews (Page 3)

Amitriptyline has an average rating of 8.1 out of 10 from a total of 124 reviews for the treatment of Depression. 76% of reviewers reported a positive experience, while 11% reported a negative experience.

Reviews for Amitriptyline

  • Mirry...
  • Taken for 5 to 10 years
  • March 27, 2022

"Am on amitriptyline for 10 years and now am on 100mg. I am 30 years old have weight gain, tiredness, some nightmares, vivid dreams, but apart from all sides effects, amitriptyline is a very effective antidepressant and good other mental illness. I have tried other meds for depression but they don't work for me. Give this drug a chance, be patient and it will amaze you. God bless you all viewers"

10 / 10
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22 Report
  • sac32...
  • October 31, 2015

"I am an ex heroin user and currently been on a methadone programme for fifteen years I'm on propranalol for anxiety and chlorpromazine 50 mgs for psychotic episodes also on serequel 200mg day 250 mg at night my psychiatrist put me on amitriptyline 50mgs for depression and really bad anxiety I haven't felt so good in years get a great nights sleep and I take it during day helps anxiety attacks I was constipated really bad for years and now I can go every day excellent results for me"

10 / 10
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61 Report
  • bpmabq
  • August 17, 2017

"I have taken many SSRI's, none were all that great. Fluvoxamine helped my OCD some. So my prescribing psychologist put me on amitriptyline. It really works for me. Helps me sleep some, and I'm not having the chronic depression and low mood. Sometimes the oldies are the best."

10 / 10
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51 Report

Frequently asked questions

  • OrcaL...
  • Taken for 1 to 2 years
  • December 22, 2015

"Diagnosed with depression/anxiety 10 years ago. Have practically been on every SSRI, SNRI, Seroquel, ALL kinds of benzos (do NOT recommend- highly addictive!) I felt so frustrated that none of the anti-depressants were working for me and avoided tricyclics for fear of weight gain. Last week I finally realised that I need serious help as I was planning suicide. I'm back on 100mg endep and 25mg Seroquel if needed at night. I sleep fantastic, wake up feeling so refreshed. Sleeping makes a HUGE difference, and the funny thing is now that I'm feeling good, I'm out of bed and exercising. I know it's scary to think about weight gain but it really is different for everyone and it's worth a shot! Endep's been the only one for me. Good luck!"

8 / 10
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59 Report
  • amitr...
  • Taken for 1 to 6 months
  • January 3, 2024

"I've been diagnosed with anxiety and depression since I was 16 years old. My first antidepressant was Paxil, which was great. It made me calmer and relieved my depression symptoms. After about 10 years, Paxil 40 mg/day started to lose its effect and anxiety symptoms slowly came back. I increased the dose to 60 mg/day and it somewhat worked, but it came with side effects like weight gain and feeling tired all the time. So, I tried sertraline, fluoxetine, and desvenlafaxine, but none of them worked well for me even at the maximum dose. Then, my doctor prescribed me escitalopram, which worked great, but I still felt the need to use alprazolam 0.5 mg per day to control my anxiety. In order to stop taking alprazolam, my doctor prescribed me escitalopram 20 mg per day + amitriptyline 75 mg per day, and these medications worked very well for me. My anxiety is now under control and I'm feeling good. Amitriptyline is still a good medication till this day."

9 / 10
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6 Report

Are you taking this medicine?

  • affff
  • Taken for 1 to 6 months
  • October 15, 2015

Endep (amitriptyline) "I was on 75mg of Endep & noticed 2 extreme side effects which lead to me having to stop taking the medication. The first was rapid & excessive weight gain; I gained 6 kgs (13 pounds) within 8 weeks (at 160cm, this is quite a bit of weight). I had no change in my diet, my exercise stayed the same, so the Endep was the only thing that could have caused the weight gain. The second was extreme Night Terrors. These occurred every night & were extremely frightening for myself & family, as I would wake up screaming & kicking every night. This occurred almost immediately after starting the Endep. Since stopping the Endep 2 weeks ago, the Night Terrors have ceased completely, & I have lost 1kg with no change in diet."

4 / 10
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56 Report
  • 5catmom
  • Taken for 1 to 2 years
  • July 20, 2016

"I've been on 300 mg of Effexor for depression and anxiety for years. Last year I was diagnosed with fibromyalgia. My rheumatologist gave me amytriptyline because I couldn't sleep. Wow!! What a difference. I can sleep. I'm upbeat. I feel great. I am one of the few who has hallucinations - only at night, only when I wake up not long after I've fallen asleep. Usually I see bugs - bees, spiders, etc. They are always black because it's dark in the room. Once I saw white feathers coming from the air conditioner. They usually stop as soon I become coherent. It was scary at first, but now I'm more conscious of it, so I usually just fall back to sleep. It's worth it to have my fibro and depression undet control."

10 / 10
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52 Report
  • BUTT...
  • Taken for 1 to 2 years
  • October 22, 2014

"I take this for Bipolar disoder 2, with severe depressive episodes. Helps tremendously for my depression symptoms, as well as aiding in controlling mood swings along with a mood stabilizer. Helps with insomnia tremendously. Sometimes the daytime sedation can last a long time at higher doses, and you'll probably get dry mouth, constipation, or blurry vision/dizziness, at least at first. This medication works great for a lot of people when other things fail, just be aware that the trade off is that some annoying side effects are fairly common. Myself, the benefits far outweigh the negatives."

8 / 10
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60 Report
  • biagina
  • June 10, 2008

Elavil (amitriptyline) "I was on Elavil for many years to help ward off migraines and it did great. Then my neurosurgeon prescribed ultram and I had a tachycardia incident. I am very sad that I can not be on Elavil. I used to take 10mg at bedtime and it was helpful."

10 / 10
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82 Report
  • Migra...
  • Taken for less than 1 month
  • April 26, 2017

Elavil (amitriptyline) "I was prescribed Elavil for depression and migraine prevention. After taking only two 10mg doses of elavil, I had a severe manic episode. (Note: I am not bi-polar.) I was shaking, pacing, unable to sleep, talking a mile a minute but making no sense, full of anxiety and rage, unable to eat or keep anything down and in a total panic. My husband took me to the ER when my heart rate went through the roof and I became short of breath. The hospital kept me overnight on a heart monitor and gave me sedatives to calm me down. My doctor wants me to try another medication but I am terrified at the prospect. Honestly, I'd rather be depressed and have migraines than try another anti depressant. One bad experience was ENOUGH."

1 / 10
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44 Report
  • Anonymous
  • May 26, 2010

"I used this medication in '94/'95 and in '97/'98 to treat major depressive episodes. It was the first antidepressant I ever tried, and it worked wonders the first time I used it. I could sleep and eat again, depression was gone within 2-3 weeks, no side effects. I was given amitriptyline again in '97/'98 after months of trying several newer anti-depressants which doctors were convinced would be better, even though I told them amitriptyline had worked for me previously. It worked very well then too, but I developed side effects (irregular heart rhythm.) I chose to take beta blockers along with amitriptyline so I could complete the course of treatment."

8 / 10
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73 Report
  • Pedal...
  • Taken for 5 to 10 years
  • February 18, 2020

"I was originally prescribed amitriptyline to help with my depression and back pain but I think it also helped my sleep, a few doctors seem keen to take me off it I don’t know why because I’ve been on it for over 10 years and I sleep well while I’m on it and my pain is kept in check as is my depression, as soon as they try to take too much of it away I’m awake again all hours like at 4.13 am like at the moment and I start getting headaches and feeling unwell again so I told my doctor the other day that I’m not reducing further than 1 tablet!!"

10 / 10
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29 Report
  • Jeni
  • Taken for 10 years or more
  • August 20, 2023

Elavil (amitriptyline) "It worked great for my depression and helped me sleep, but the effect is now not as strong as it was. While it lasted 15 years, it was amazing, a miracle! Now I'm on Prozac and my panic attacks are crazy. I think I will go back to Elavil!"

10 / 10
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8 Report
  • Indig...
  • Taken for less than 1 month
  • November 17, 2015

Elavil (amitriptyline) "Elavil works in my case as a pain killer/anti depressant. I does have some cons that I was not warned about. I was told by my doctor to take 150mg before bed so I did as told and woke up only when my wife shook me for a second I would eat and go right back to sleep this happened for the first 24 hours the next I had no choice but to stay awake. being awake I had problems with balance and depth perception. my mind was racing with what felt like hundreds of thoughts. my ability to speak was reduced to short sentences. it felt like my jaw was not moving fast enough to make more than a few sentences. after taking that dosage down from 150mg to 37.5mg I am able to speak clearly but my mind is still a little foggy. and the back pain is not as bad"

10 / 10
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44 Report
  • edward
  • March 9, 2023

Elavil (amitriptyline) "I have been diagnosed with depression since college. Since then I have tried every anti-depressant and had no luck. My doctor put me on elavil, and boom depression is gone though I have IBS-C big time. Tried to taper down from 100 mg, and got down to 60 mg, but am still constipated. It's a nightmare, I am now taking Linzess290, Motegruty, miralax, and coconut oil which helps a little bit. Has anybody else had the same problems?"

9 / 10
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10 Report
  • Antonia
  • Taken for 2 to 5 years
  • May 18, 2018

"I was prescribed Elavil after 3 years of terror with SSRI and SNRIs. I have to say that it helped me tremendously with sleeping, energy and headaches. I suffer from anxiety/depression. It helped with anxiety a lot. I threw away the clonazepam after 2 weeks. However for my bad luck it didn’t give me the remission —my old self. I was disconnected for three years and a half.. I was like circled not living the daily routine. If I would feel my old self I wouldn’t mind for the dry mouth and weight gain. Anyway I tapered it off and after 4 months I crashed. I tried Fetzima, Cymbalta without result. Now my doctor wants to put me back to Elavil and I’m crying all day because I know will help me with most of the symptoms except for not feeling my old self—just flat all day. I can’t imagine my life feeling disconnected from my children.. what should I do?"

6 / 10
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32 Report
  • pinky
  • Taken for 1 to 6 months
  • December 26, 2019

Endep (amitriptyline) "My Father has been on Endep (low dose) for a few months and has slept 20 hours a day however he is pain free for the first time in a long time. I don't now if the trade off is worth it but his pain unbearable, but now he has no life. Just sleep."

6 / 10
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25 Report
  • Thank...
  • Taken for 2 to 5 years
  • May 12, 2020

"I take 25mg Elavil to augment my Luvox and aide in sleep. I have very severe depression and sleep issues and this dosage works really well for me. It’s not strong enough to put me to sleep, but it helps me wind down. As an added bonus, it helps keep away my migraines and nerve pain. I’ve been on this medication for 2 years. My main side effects are weight gain (went from 115-135lbs in a year), nighttime eating, and an occasional dry mouth. Be warned. This medication makes you very hungry!"

9 / 10
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23 Report
  • Scott
  • Taken for less than 1 month
  • April 8, 2021

"Been on multiple antidepressants over the years but none have helped me like this old drug. It does have a lot of side effects, but I'm willing to put up with them because it completely wipes out my anxiety and depression."

10 / 10
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19 Report
  • Jaxte...
  • Taken for 1 to 6 months
  • November 2, 2021

"This medication got rid of my depression. I take 25mg an hour before bedtime. It took 2 months but I can honestly say I am back to my normal self. This truly works. Hang in there and wait. Depression is cruel and happens to everybody at some stage in life. Do not give up hope."

10 / 10
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16 Report
  • Lk1015
  • Taken for less than 1 month
  • November 19, 2020

"Is amitriptyline finally the one??? I'm on day 6. Have only had I minor day of feeling like a robot. Starting to notice some change in mood but nothing significant yet. Drowsy all day but hear this wears off after time. I'm on only 10mgs before bed. I just want to have a normal life of being happy and wanting to do fun things in life. I am also on clonazapam which I'm sure doesn't help with the grogginess. I have taken citalpram and wellbutrin before. Both gave me extreme panic attacks and bad thoughts of harming myself and others. Was afraid that would happen with this med. But so far, so good. Excited to see how the next few weeks goes and hope this will be a life changer."

7 / 10
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19 Report
  • mag
  • February 28, 2018

"I was prescribed this drug for migraine prevention and when I took the first dose of 10 mg I could not wake up the next day and then stopped. But I did notice for about 5 days after that my mood was better. I was having all these un-diagnosed health problems and doctors thought I was having silent migraine, but now, I do believe I was battling depression. I did have a few bouts of depression over a 20 year period and was taking Zoloft and that helped, but this time I did not feel like the last time when I was depressed, as I did not have the "classic" depression symptoms. I am also going through menopause and I believe this is what is causing my depression. I cut the pills in half and started with 5 mg until I got used to the effect and then upped them to 10 mg after and week and I feel great and after 6 months, I feel like myself again. It has only been 2 weeks, but I am hoping that this is the answer."

9 / 10
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29 Report
  • Xalares
  • Taken for 2 to 5 years
  • August 19, 2020

"Hi everybody, I come to share my experience of Amitriptyline to treat anxiety and depression. I've spent 3 years of my life under this medication. It was 3 painful years during those I was constantly tired, because of the Amitriptyline. Last year I started withdrawal and I've spent 1 year and a half reducing the drug, but as I was getting closer to the end, some abdominal aches appeared, and now even if it's been months that I've stopped the medication, I still have those pains (which are not diagnosed but I think its the irritable bowel syndrome). I've poor sleep because of the pain, and I despair to stop them. The only thing that used to stop them was taking Amitriptyline again."

4 / 10
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18 Report
  • abdul...
  • November 11, 2021

"I'm taking this medication for 1.5 months, no side effects except dry mouth some times, literally its great med, gave me the hope again to get in full remission. My power increased obviously, my mood is much better It literally saved my life, just give it enough time"

10 / 10
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13 Report
  • Anonymous
  • Taken for 10 years or more
  • May 9, 2022

"Please don't be afraid to take Amitriptyline it has taken control of my major depression disorder and helps me sleep as it relaxes the uncomfortable painful pains of my daily major depression disorder. Amitriptyline to anyone that suffers from daily serious major depression disorder and anxiety disorder and everyone please don't be afraid of Amitriptyline daily. I've taken it for at least the last 10 years and I get full relief from my daily serious major depression disorder from Amitriptyline 150MG once daily and I feel blessed and I'm happier with my life day to day then ever. Thank you Amitriptyline for making me have a happy life everyday."

10 / 10
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11 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.