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Amitriptyline User Reviews & Ratings (Page 5)

Amitriptyline has an average rating of 7.6 out of 10 from a total of 1,737 reviews on Drugs.com. 68% of reviewers reported a positive experience, while 16% reported a negative experience.

Reviews for Amitriptyline

  • Paul
  • Taken for 6 months to 1 year
  • September 3, 2019

For Insomnia "Been taking this for about 10 months now primarily for sleeping issues. But it's also been good for my hayfever as it has antihistamine actions. I take 25mg at night & can feel it kick in about 45 mins after ingestion, I feel a bit drowsy & my limbs get a bit heavier. Then I get in bed & fall asleep easily. The only issue I have is if I try to stop this drug I just don't sleep at all. Maybe I'm dependant on it but that's ok as long as it works it's better than looking at the ceiling all night."

8 / 10
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  • It Wo...
  • Taken for 5 to 10 years
  • October 26, 2013

For Depression "I was one of those people who thought nothing would work for me - I was too far gone and beyond help. Restless, sleepless nights and all the anxiety and depression were killing me. And then I found Amitriptyline. At last.....Sleep. That's all that mattered to begin with. You simply cannot underestimate the power of sleep. During the day I felt far less agitated and less stressed. Of course life can still throw slings and arrows your way and there are side effects for sure but none as bad as the frazzled state I was in before I took them."

10 / 10
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  • Timel...
  • Taken for less than 1 month
  • June 15, 2018

For Anxiety and Stress "I was having the most horrible panic attacks and pretty constant anxiety where if it had continued, I really don't want to contemplate what I would have done to stop it all. After Taking amitriptyline 50mg for 7 days it all stopped dead! Thank you Amitriptyline! I have my life back and now feel normal again. I highly recommend it!"

10 / 10
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Frequently asked questions

  • Trans...
  • Taken for 1 to 6 months
  • December 21, 2013

Elavil (amitriptyline) for Pain "I started taking this medicine 4 months ago for my nerve pain in low dose of 10 mg twice a day and maybe a bit for depression. It does not help at all for the pain but it does help to fall asleep faster and for my mood."

7 / 10
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  • Feath...
  • September 8, 2013

For Pain "I can't believe that after 3 years of severe widespread neuropathic pain of unknown origin, I am sleeping 8-10 hours and have had total pain reduction from about a 8 at worst to now a 1.5 I've only been on 10 mg at night for 3 days. I hope it's not coincidence or placebo affect. A bit drowsy and a dizzy spell today. But completely worth it. I'm falling asleep faster now. My mood seems to be more calm as well. I hope to get off of oxycodone now."

9 / 10
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Are you taking this medicine?

  • Ryan
  • Taken for 1 to 6 months
  • December 27, 2019

For Insomnia "I was in a four wheeler crash in 2017. Lot of tissue and nerve damage on my left side. Nothing major but the pain was minor enough I just could never get comfortable and would wake up 20+ times throughout the night and was never getting a good sleep. Asked my Dr about it last October and he put me on a dose of 25 mg of amitriptyline to help calm my nerves. It took a couple of months but now when I lay down I get comfy easily and I fall asleep within 30 mins of laying down . I sleep all through the night and don't wake up until my alarm goes off. Lately I've been waking up at 8 before my alarm goes off. Best sleep I've had in a decade."

10 / 10
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  • Hayley
  • October 5, 2019

Endep (amitriptyline) for Pain "I am 37 years old I started getting headaches at 13 from what I can remember I went on day to day year after year when I was 26 I was put in hospital with all the drugs Well I was getting headaches monthly bad ones I couldn’t even handle light As the years went on I got them once every 6 months putting me in hospital Then they started coming on every couple of months then once a month all the way down to 3 a week By this stage my face was numb I couldn’t talk or walk could not have any light, losing memory about 3 months ago I went to a brilliant doctor and I couldn’t see so I needed help going there and walking to him He said to me have you heard of ENDEP I have taken my endep every night since for over 3 months now And only had two very very small headaches I’ve been given a second chance at life I’m very grateful I thank my doctor so very much"

10 / 10
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  • Anonymous
  • September 1, 2014

For Insomnia "I have taken this medication during certain times in my life due to events and change of time zones for long periods of time when my sleep pattern is broken. It is great. I have been able to stay at 25 mg without increase for more than a year and work myself off when fully recovered. Be prepared to wait for it to kick in up to 2 weeks after starting it. It needs to fully get into your system. Everyones body is different. Recently I tried zolpidem for a more immediate sleep and found I could only get 4 hours a night. I read about the addiction of it and possible rebound insomnia after weaning yourself off. I am going back to that old model medicine, Amitriiptyline. It is great and I get back to a 7-8 hour sleep pattern."

9 / 10
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  • uniqu...
  • October 18, 2013

For Anxiety and Stress "I started taking amitriptyline this year (2013) after having a medicine cabinet looking like a pharmaceutical company. I must say this is the only one that helps me. I have severe anxiety and panic attacks along with constant worry and stress that had me on rock bottom. I take 25mg which is fine, it does make you sleepy but it's so worth it. I'm 27, no kids just coping with life."

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  • Matvei
  • Taken for 1 to 2 years
  • August 19, 2020

Elavil (amitriptyline) for Insomnia "I've had insomnia almost every way you can have it, so I've tried the whole raft of sedatives and hypnotics. Only three have worked: diphenhydramine (Benadryl), doxepin/Silenor, and this. Just the fact that it keeps me asleep is such a godsend that I can't give it a bad review, but ... Of the three drugs that work, this is the worst. It has more neurological side effects, it puts me in a lousy mood that lasts most of the next day (not terrible, but maybe 25% grumpier than usual), and it leads to weight gain even at the lowest dose (10mg). If my hormones are out of whack (high cortisol) amitriptyline doesn't make me groggy, but if they're in line it really does, leaving me wool-headed until the middle of the afternoon. It also has negative interactions with a bunch of other drugs, so be careful to check it against your other prescriptions/recreational drugs."

7 / 10
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  • Tony
  • Taken for 1 to 2 years
  • July 18, 2019

For Insomnia "Since I was prescribed amitriptyline by my doctor a few years ago I feel it's the only thing that works for me I've been prescribed Somas, Valium, Xanax, Tramadol, Percocet, Vicodin even though I like the way these make me feel when I take the amitriptyline I don't feel withdrawal I am able to fall asleep and stay asleep. I've gained an appetite again back pain is minimal I really don't see any negatives to this drug. A lot of people say they have bad dreams so on so forth I feel this is the best drug 4 me. I was diagnosed with sciatica degenerative disc disease a cracked disc in my back bulged discs in my neck and rheumatoid arthritis but with a little bit of exercise and stretching. Now I do not take any other medication besides 10 mg amitriptyline do not wake up feeling groggy still able to function I definitely recommend this drug to anybody with the same conditions plus depression and insomnia in my eyes this is a miracle drug for me."

10 / 10
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  • Anonymous
  • December 11, 2023

For Insomnia "I probably tried every prescription drug; every natural remedy... everything. I suffered from brutal insomnia for 30 years. After 2 years on Amitriptyline, I can honestly say this medicine has given me my life back. I'm shocked to sleep well every night. Incredible relief."

10 / 10
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  • Fortu...
  • Taken for 10 years or more
  • June 15, 2020

Endep (amitriptyline) for Depression "I have been taking Endep for well over 12 years without any side effects whatsoever. It has helped me greatly my maintenance dose is 100mg. It also helps my pain as well as being able to get about 6 hours sleep at night. l am an elderly person but Endep has contributed to giving me a better quality of life -"

10 / 10
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  • Bende...
  • October 13, 2013

For Migraine Prevention "I don't like taking medication, but my headaches were now in a state of chronic tension/migraine being triggered by anything excessive like exercising, too much cleaning, too much activity, too much light or stress. I was prescribed Elavil for headaches, irritable bowel syndrome, sleep trouble, back, neck, and arm pain. I've taken it for a week, and after one dose, the first thing I noticed was an awesome night's sleep, and no neck or jaw pain, pain on rising. I feel completely relaxed in the morning, a little drowsy but am able to function and get my three kids to school. I have been taking it at 10pm and feel tired until noon, so I think I'm going to take it earlier in the evening. I haven't noticed any side effects at all. I am taking 10 mg."

8 / 10
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  • Happier
  • Taken for less than 1 month
  • June 6, 2019

For Pain "I had exhaustion, roving pains, burning eyes, and tummy troubles for 5 months and it was starting to interfere with my daily life. We did blood work and ultrasounds but nothing showed. The Dr. decided to try Amitriptyline. The first few days I experienced dry mouth and random prickly sensations. That went away and I was left with slight constipation, and a near constant craving sensation, BUT... I am 3 weeks into it now and even though I'm not exactly back to 'normal', I do have a happier outlook, more of my playful self, and I'm kinda.. "detached" from my pain. I dream more, but sleep more soundly. I do feel it 'hit' me about half an hour after I take it but it's not enough of an effect to knock me out or anything though. Overall, I am very happy with the results so far. I take 10mg between 8 and 9 pm (any later and it's a bit too hard to wake up in the morning). I'm very happy we tried this and I'm hopeful that it will continue to improve my daily life."

9 / 10
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  • Hugs
  • Taken for less than 1 month
  • December 11, 2018

For Interstitial Cystitis "I have had IC and Vulvodynia for around a year and a half. My symptoms include painful intercourse, pelvic pain, burning urethra. I tried Elmiron and it made my symptoms 10 times worse, so I stopped within three weeks of my start date. I recently was prescribed Amitriptyline 25mg and I have been on it for a month. I take it at night around 9 PM and find that it makes me drowsy. It also keeps me in a deep sleep (which I love). In the morning, it is a little harder to wake up, but once I am up, I am fully functional and not tired. During the first two weeks, I didn't experience any relief, but by the third week, my symptoms disappeared. I am in shock that something actually worked being that I have tried almost EVERYTHING. I now can drink an 8-ounce cup of coffee a day and not feel any burning or pain when I urinate. If you have been suffering for some time with IC/Vulvodynia, I highly suggest trying this medication."

10 / 10
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  • MrsF
  • March 21, 2011

Elavil (amitriptyline) for Anxiety and Stress "I'm bipolar. I've been on various medicines for almost 10 years. Well, my Dad died a few months ago. The depression and anxiety was so bad I could not function. My Doctor prescribed this along with my 40mg of Celexa. It took about a month -6 weeks before I felt any better. But I also have chronic pain from spinal arthritis. This medication has helped me get my life back! But in the process, I've gained 20lbs in 8 weeks and I was already overweight. Its helped with my chronic pain and with the depression. I love how I feel on this but not the weight gain. "

8 / 10
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205 Report
  • pain...
  • Taken for 2 to 5 years
  • September 19, 2014

Elavil (amitriptyline) for Pain "I took Elavil 100 mg for migraine and sleep back in 90's wow solved my problems. Quit taking, and now I'm on 200 mg sleep and neuropathy from diabetes, sleep and stress. I take other medicines. I'm not healed just no more pain. Sometimes fall asleep and times just breeze through the day. Elavil helps for many medical problems. Don't like the new medicines. The old medicines work best for me."

10 / 10
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  • BAano
  • Taken for 2 to 5 years
  • September 8, 2018

For Migraine Prevention "Amitriptyline is my miracle medicine. After trying so many migraine prevention medicines and other miscellaneous things (ear piercings, stretches, pressure point therapy, etc.) with little to no effect, I was beyond frustrated. With this medication 90% of all my tension headaches and migraines are gone. When I had to stop taking it for 3 months, they came back. Once I started amitriptyline again, within day they were basically gone. It has changed my life in a tremendously positive way!"

10 / 10
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108 Report
  • sirius
  • Taken for 6 months to 1 year
  • August 5, 2018

Elavil (amitriptyline) for Insomnia "I'm 65 years old so when the benzo stop being effective, I used Amitriptyline ( elavil) to sleep. I have to take 3 X 10mg with half of a banana to make it smoother on the empty stomach, to make it work. It has some nasty side effects but they tend to go away after a while. Constipation will not be a problem anymore after a 1 months, drink a lot of water early in the evening to prevent constipation. Dry mouth will always be there, but will become less severe after a while, so chew some gum to fix this problem. Sex will also take a low profile :-) This drug can also be use to make the withdrawal of the benzos much easier to do. You will still sleep and will only need a small dosage of benzo which you can lower slowly but surely. I get a better sleep pattern than the benzos. Waking up ready to drive my car if I need to , unlike the Ambien. Cheap to buy also. My old mother still use it after almost 50 years of usage. She is 85."

9 / 10
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  • outat...
  • Taken for 2 to 5 years
  • February 24, 2016

For Anxiety and Stress "I struggled horribly with severe anxiety for years I tried all kinds of natural remedies and doctor prescribed medicines but nothing worked long term then two years ago I was diagnosed with interstitial cystitis and was prescribed AmItriptyline for pain but what I got was amazing relief from my anxiety and stress now I know what people mean when they say "I got my life back" I take 5mg before bed I sleep great and have a little trouble waking up cause I sleep so well but once I'm up I'm fine no drowsiness and no more anxiety"

9 / 10
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  • Rastus
  • Taken for 2 to 5 years
  • July 28, 2019

For Depression "I had experienced anxiety and depression..It was horrible!! I started on Elavil for a number of months, I got my life back!!!!! I absolutely thought I would never over come the anxiety! I'm on 100 my at night now n feel soooooo good! Back to my old self!"

10 / 10
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94 Report
  • Charlie...
  • Taken for 10 years or more
  • March 25, 2015

For Migraine Prevention "Amitriptyline is nothing short of a miracle for me. I used to be plagued by terrible migraines. I've been taking amitriptyline for about 25 years, and I have not had a single migraine in all that time."

10 / 10
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152 Report
  • Anonymous
  • July 16, 2016

For Fibromyalgia "I believe fibromyalgia symptoms started when I was around 14, it wasn't diagnosed until I was 41. I had been to many doctors complaining of lethargy and body pain/aches, and I never had any answers, one doctor said "do you think this might be all in your head."My life changed at 41 when I started on amitriptyline, I finally went into a deep sleep, felt more refreshed, and it substantially reduced the pain. I am currently 55, original dose lost its efficacy overtime. I am now on 125 mg, but I am very active and run and bicycle weekly. Don't get scared if you feel even more tired in the first 2 to 3 weeks of taking the medication, that will dissipate and you will feel refreshed all day."

8 / 10
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  • IBS...
  • Taken for 6 months to 1 year
  • November 30, 2014

For Irritable Bowel Syndrome "I was skeptical and did not want to take this. My doctor prescribed Amitriptyline and Citalopram in approx. 1/4 dosage given for depression. I had just gone through the worst 4 four months of my life with debilitating Irritable Bowel Syndrome attacks nearly every day that would last for two to up to 8 hours. I gave in and tried the medications. I have not had a single IBS attack since the very first night I took the medications. It feels like a miracle. My attacks were so bad the thought of dying seemed better than having the attacks regularly. I thank my incredible doctor and God for introducing me to this medicine. "

10 / 10
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154 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.