Does Spironolactone really work for women w/high testosterone?

Spironolactone can be helpful for women with "unwanted hair" - a phenomenon called hirsuitism. It is important to be aware of all the potential side effects of the medication. The drug must not be used during pregnancy.

A small number of studies have shown that for the treatment of hirsuitism, 200 mg may be more effective than 100 mg and 100 mg more effective than 50 mg.

50 mg may be beneficial, but speak to your physician if you do not achieve the desires outcome in terms of hair reduction.

Jeff Donovan MD PhD FRCPC FAAD
US & Canadian board-certified Dermatologist
Toronto, Canada

Yes it can.
Spironolactone is an anti-androgen, which means that it counteracts the effects of male hormones (androgens).
It can decrease the level of testosterone and block androgen receptors.
Because of these effects it is frequently used to treat a variety of cosmetic conditions in which androgen hormones such as testosterone play a role, including excessive hair growth, androgenic alopecia (hair loss), acne, and seborrhea (skin rash).
It is well worth trying. All the best.