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Vitamin K1 Oral Capsules

This page contains information on Vitamin K1 Oral Capsules for veterinary use.
The information provided typically includes the following:
  • Vitamin K1 Oral Capsules Indications
  • Warnings and cautions for Vitamin K1 Oral Capsules
  • Direction and dosage information for Vitamin K1 Oral Capsules

Vitamin K1 Oral Capsules

This treatment applies to the following species:
Manufacturer: Clipper (Phoenix Pharm.)

Each capsule contains 25 mg of Phytonadione

FOR USE IN DOGS AND CATS

FOR ANIMAL USE ONLY

KEEP OUT OF REACH OF CHILDREN

Description

Vitamin K1 Capsules contain phytonadione with excipients in an artificially colored soft gelatin shell.

ACTIONS:

Vitamin K1 Capsules for oral administration possess the same type and degree of activity as does naturally occurring vitamin K. The primary function of vitamin K is to stimulate the production via the liver of active prothrombin from a precursor protein. The mechanism by which vitamin K promotes formation of prothrombin at the molecular level has not been established.

Vitamin K1 Oral Capsules Indications

Vitamin K1 Capsules are indicated in dogs and cats to counter hypoprothrombinemia induced by digestion of coumarin-based compounds, common ingredients of commercial rodenticides, and other drug induced hypoprothrombinemia where it is definitely shown that the result is due to interference with vitamin K1 oral capsules. The dosage should be adjusted accordingly.

NOTE:

Regular determinations of prothrombin time response should be performed to guide in the initial and subsequent administration of Vitamin K1 oral capsules. The dosage should be adjusted accordingly.

CONTRAINDICATION:

Hypersensitivity to any component of this medication.

Warnings

It is recommended that Vitamin K1 oral capsules be used in follow-up therapy only after administration of Vitamin K1 Injection and hospitalization are no longer required. An immediate coagulant effect should not be expected after administration of phytonadione when administered orally.

Phytonadione will not counteract the anticoagulant action of heparin.

Repeated large doses of Vitamin K1 are not warranted in hepatic disease of the response the initial therapy is unsatisfactory. Failure to respond to Vitamin K1 may indicate that the condition being treated is inherently unresponsive to Vitamin K1.

Precautions

Protect from light at all times. Temporary resistance to prothrombin-depressing anticoagulants may result, especially when larger doses of phytonadione are used.

Dosage and Administration

Dogs and Cats

Hypoprothrombinemia (with hemorrhage) - Administer orally at the rate of 2.5-5 mg/kg body weight (1 capsule per each 22 pounds of body weight for lower dosage or 1 capsule per each 11 pounds of body weight for higher dosage) daily as conditions require up to 3 weeks.

Frequency and amount of oral administration should be guided by regular determination of prothrombin time.

The smallest effective dose should be sought to minimize the risk of adverse reaction.

Vitamin K1 Oral Capsules Caution

Vitamin K1 oral capsules are sold only to licensed veterinarians.

How Supplied

Vitamin K1 oral capsules are available in bottles of 50 capsules each.

Manufactured By: Jice Pharmaceuticals, Lowell, MI 49331

Manufactured For: PHOENIX PHARMACEUTICAL, INC., St. Joseph, MO 64507

Net Contents:

NDC

 

50 Capsules

57319-395-12

Rev. 02-05

NAC No.: 12560974

CLIPPER DISTRIBUTING CO., LLC
PHOENIX PHARMACEUTICAL INC.

1302 SOUTH 59 STREET, ST. JOSEPH, MO, 64507
Telephone:   816-364-5777
Order Desk:   800-759-3644
Fax:   816-364-4969
Website:   www.clipperdist.net
Email:   info@clipperdist.net
Every effort has been made to ensure the accuracy of the Vitamin K1 Oral Capsules information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2016 North American Compendiums. Updated: 2016-10-31

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