Vitamin K1 Oral CapsulesThis page contains information on Vitamin K1 Oral Capsules for veterinary use.
The information provided typically includes the following:
- Vitamin K1 Oral Capsules Indications
- Warnings and cautions for Vitamin K1 Oral Capsules
- Direction and dosage information for Vitamin K1 Oral Capsules
Vitamin K1 Oral CapsulesThis treatment applies to the following species:
Each capsule contains 25 mg of Phytonadione
FOR USE IN DOGS AND CATS
FOR ANIMAL USE ONLY
KEEP OUT OF REACH OF CHILDREN
Vitamin K1 Capsules contain phytonadione with excipients in an artificially colored soft gelatin shell.
Vitamin K1 Capsules for oral administration possess the same type and degree of activity as does naturally occurring vitamin K. The primary function of vitamin K is to stimulate the production via the liver of active prothrombin from a precursor protein. The mechanism by which vitamin K promotes formation of prothrombin at the molecular level has not been established.
Vitamin K1 Oral Capsules Indications
Vitamin K1 Capsules are indicated in dogs and cats to counter hypoprothrombinemia induced by digestion of coumarin-based compounds, common ingredients of commercial rodenticides, and other drug induced hypoprothrombinemia where it is definitely shown that the result is due to interference with vitamin K1 oral capsules. The dosage should be adjusted accordingly.
Regular determinations of prothrombin time response should be performed to guide in the initial and subsequent administration of Vitamin K1 oral capsules. The dosage should be adjusted accordingly.
Hypersensitivity to any component of this medication.
It is recommended that Vitamin K1 oral capsules be used in follow-up therapy only after administration of Vitamin K1 Injection and hospitalization are no longer required. An immediate coagulant effect should not be expected after administration of phytonadione when administered orally.
Phytonadione will not counteract the anticoagulant action of heparin.
Repeated large doses of Vitamin K1 are not warranted in hepatic disease of the response the initial therapy is unsatisfactory. Failure to respond to Vitamin K1 may indicate that the condition being treated is inherently unresponsive to Vitamin K1.
Protect from light at all times. Temporary resistance to prothrombin-depressing anticoagulants may result, especially when larger doses of phytonadione are used.
Dosage and Administration
Dogs and Cats
Hypoprothrombinemia (with hemorrhage) - Administer orally at the rate of 2.5-5 mg/kg body weight (1 capsule per each 22 pounds of body weight for lower dosage or 1 capsule per each 11 pounds of body weight for higher dosage) daily as conditions require up to 3 weeks.
Frequency and amount of oral administration should be guided by regular determination of prothrombin time.
The smallest effective dose should be sought to minimize the risk of adverse reaction.
Vitamin K1 Oral Capsules Caution
Vitamin K1 oral capsules are sold only to licensed veterinarians.
How SuppliedVitamin K1 oral capsules are available in bottles of 50 capsules each.
Manufactured By: Jice Pharmaceuticals, Lowell, MI 49331
Manufactured For: PHOENIX PHARMACEUTICAL, INC., St. Joseph, MO 64507
NAC No.: 12560974
PHOENIX PHARMACEUTICAL INC.
1302 SOUTH 59 STREET, ST. JOSEPH, MO, 64507
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