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Vitamin K1 Injection (Canada)

This page contains information on Vitamin K1 Injection for veterinary use.
The information provided typically includes the following:
  • Vitamin K1 Injection Indications
  • Warnings and cautions for Vitamin K1 Injection
  • Direction and dosage information for Vitamin K1 Injection

Vitamin K1 Injection

This treatment applies to the following species:
Company: Vétoquinol

Phytonadione Injection, USP

Sterile Aqueous Colloidal Solution

10 mg/mL

Veterinary Use Only

DIN 01950150


VITAMIN K1 INJECTION is a sterile aqueous colloidal solution containing per mL:


10 mg


Benzyl alcohol

9 mg

Vitamin K1 Injection Indications

Cattle, horses, swine, sheep, goats, dogs and cats:

As an aid in the treatment of coagulation disorders associated with hypoprothrombinemia due to Vitamin K deficiency or interference with Vitamin K activity, or anticoagulant induced hypoprothrombinemia such as sweet clover disease in cattle and poisoning with anticoagulant rodenticides in dogs.


Cattle, horses, swine, sheep and goats:

Acute hypoprothrombinemia (with hemorrhage):

0.5 to 2.5 mg per kg of body weight, by slow intravenous injection at a rate not to exceed 10 mg/minute in mature animals and 5 mg/minute in newborn and very young animals.

Non-acute hypoprothrombinemia:

Intramuscularly or subcutaneously: 0.5 to 2.5 mg/kg of body weight.

Dogs and cats:

Acute hypoprothrombinemia (with hemorrhage):

0.25 to 2.5 mg per kg of body weight by slow intravenous injection at a rate not to exceed 1 mg/minute.

Non-acute hypoprothrombinemia:

Intramuscularly or subcutaneously: 0.25 to 2.5 mg per kg of body weight.

Whenever possible, the intramuscular or subcutaneous administration route should be employed.

For intravenous administration dilute with preservative free 5% dextrose, 0.9% sodium chloride injection or 5% dextrose in 0.9% sodium chloride injection. Do not use other diluents.

Administration should be started immediately after mixture with diluent. Avoid rapid infusion. Discard unused portion of the mixture.

Determine frequency and amount of subsequent doses by monitoring prothrombin time response and clinical condition.

Vitamin K1 Injection Caution

Allergic sensitivity, including severe anaphylactoid reactions may occur with Vitamin K1 preparations. In such cases, discontinue the treatment immediately and administer epinephrine.

Pain, swelling and tenderness at the injection site may occur. Do not inject more than 5 to 10 mL at one injection site.

No Vitamin K preparation is a substitute for the use of whole blood transfusions in cases of severe hemorrhage associated with anticoagulant therapy or poisoning; it should be considered only as adjunctive therapy. Phytonadione may be contraindicated in severe liver disease, if no significant change in prothrombin time occurs within 1-2 days of therapy due to impaired liver function.


Store between 15°C and 25°C. Protect from light; store in a dark place.


VITAMIN K1 INJECTION is offered in 100 mL-vial (code 01170)

Vétoquinol N.-A. Inc., 2000, ch. Georges, Lavaltrie, QC, CANADA J5T 3S5




100 mL



CPN: 12341533

Commercial Division

Telephone:   450-586-2252
Order Desk:   800-363-1700
Fax:   450-586-4649
Every effort has been made to ensure the accuracy of the Vitamin K1 Injection information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert.

Copyright © 2020 Animalytix LLC. Updated: 2020-10-21