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Vet-Kem Ovitrol Plus Flea, Tick & Bot Spray

This page contains information on Vet-Kem Ovitrol Plus Flea, Tick & Bot Spray for veterinary use.
The information provided typically includes the following:
  • Vet-Kem Ovitrol Plus Flea, Tick & Bot Spray Indications
  • Warnings and cautions for Vet-Kem Ovitrol Plus Flea, Tick & Bot Spray
  • Direction and dosage information for Vet-Kem Ovitrol Plus Flea, Tick & Bot Spray

Vet-Kem Ovitrol Plus Flea, Tick & Bot Spray

This treatment applies to the following species:
Manufacturer: V.P.L.

Contains PRECOR®

Insect Growth Regulator

Plus Pyrethrins, an adulticide

Kills and repels fleas, ticks, lice, flies, mosquitoes and gnats

Kills flea eggs

2 Month Protection

Ovitrol Plus may be reapplied weekly

Kills and repels: fleas, ticks, lice, flies, mosquitoes, and gnats

Quickly kills adult fleas plus kills their hatching eggs for up to 2 months

Kills and repels Lyme disease-carrying ticks

Prevents botfly eggs from hatching

Rapid action formula

Active Ingredients

(S)-Methoprene (CAS #65733-16-6)


Pyrethrins (CAS #8003-34-7)


Piperonyl Butoxide (CAS #51-03-6)


N-octyl Bicycloheptene Dicarboximide (CAS #113-48-4)







Vet-Kem Ovitrol Plus Flea, Tick & Bot Spray Caution

See additional precautionary statements

HOW OVITROL PLUS® FLEA, TICK & BOT SPRAY WORKS: Plus® controls fleas, flea larvae, ticks, lice, mosquitoes, gnats, house flies, stable flies, horn flies, face flies, and horse bots. Botfly eggs and flea eggs sprayed with Ovitrol Plus® will not hatch into adults.

Ovitrol Plus® combines the adult flea killing power of pyrethrins with the long-lasting egg-killing power of PRECOR® Insect Growth Regulator. This highly effective combination of ingredients provides quick relief from biting fleas and continuous killing of flea eggs laid on the animal, breaking the flea life cycle. The elimination of both adult fleas and flea eggs is important because adult fleas live on your pet, causing discomfort and skin irritation, while the vast number of eggs that they lay fall off and develop in your house. If fleas are already developing in your house, then use a Siphotrol® premise product. Effective flea control requires treatment of your pets, house, and yard.

Ovitrol Plus® contains PRECOR® Insect Growth Regulator, which effectively kills botfly eggs that have been glued to the hairs on the forelegs, shoulders, and faces of horses, by adult botflies (Gastrophilus spp.). If left untreated, botfly larvae emerge from these eggs and are taken into the mouth of the horse. After botfly larvae are swallowed, they attach to the stomach and small intestinal linings in tremendous numbers, where they can remain for months before passing out in the feces. Adult botflies emerge from pupae in the soil to begin the cycle all over again. Botflies have been implicated as a cause of some stomach and intestinal conditions in horses.

DIRECTIONS FOR USE - It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. SHAKE WELL BEFORE USING.

FOR DOGS AND CATS: For Fleas: A light, even coverage of the hair coat will provide effective flea control. Do not allow spray from application or damp animal to come into contact with painted or finished surfaces, including wood floors/furniture, leather/vinyl materials, or other surfaces of concern. For best results, ruffle the coat while spraying against the natural lay of the hair. Cover animal’s eyes with hand. With a firm, fast stroke, spray head, ears, and chest. With cloth, rub into face around mouth, nose, and eyes. Then spray the neck, middle and hind quarters, finishing with legs and tail last. Avoid spraying rectum and genitals. Apply at the rate of 1 or 2 squeezes of the trigger sprayer [0.10 fluid ounce] per pound of body weight. For larger dogs, spray until damp, not saturated. Do not allow animals, cats in particular, to become chilled. Repeat every 2 months for continuous home flea infestation prevention. If your pet becomes reinfested with adult fleas from outside sources, Ovitrol Plus® may be reapplied weekly. For Ticks: Make sure spray thoroughly wets individual ticks.

FOR PUPPIES AND KITTENS: For Fleas: Leaving the eyes, nose, and mouth exposed, treat puppies and kittens weighing less than 3 pounds by wrapping the animal in a towel that has been lightly sprayed with Ovitrol Plus®, for 5 to 10 minutes. Or lightly spray a brush or cotton ball and work thoroughly into the hair coat. Fleas may then be removed from the coat by picking or combing. Puppies and kittens over 3 pounds may be treated the same as dogs and cats as described above. Repeat every 2 months for continuous home flea infestation prevention. If your pet becomes reinfested with adult fleas from outside sources, Ovitrol Plus® may be reapplied weekly. Do not allow animal to become chilled.

Do not use on puppies and kittens under 12 weeks of age.

FOR HORSES AND PONIES: For Flies: Remove excess dirt and dust by brushing coat. Apply spray directly to horse’s coat, giving particular attention to legs, shoulders, flanks, neck, and topline. To treat face, dampen a cloth with spray and rub on face and head, being careful to avoid eyes. Repeat every 2 months for continuous fly infestation prevention. If your horse/pony becomes reinfested, Ovitrol Plus® may be reapplied weekly. This product is not to be used on horses destined for slaughter. For Prevention of Hatch of Horse Botfly Eggs: Spray any infested areas directly at the first sign of visible eggs, paying particular attention to legs, shoulders, flanks, neck, and topline. Spray to the point of dampness but not to the point of run-off of the spray. For a high degree of botfly egg control, spray animals every 3-5 days during the botfly season.


Do not contaminate water, food, or feed by storage or disposal. Storage: Do not store near heat or open flame. Store away from children or animals. Container Handling: Nonrefillable container. Do not reuse or refill this container. If empty: Place in trash or offer for recycling if available. If partly filled: Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain.

PRECAUTIONARY STATEMENTS - HAZARDS TO HUMANS - CAUTION: Harmful if swallowed or absorbed through skin. Avoid contact with skin, eyes, or clothing. May cause dermal sensitization (skin allergy). HAZARDS TO ANIMALS - CAUTION: Consult a veterinarian before using this product on debilitated, aged, pregnant, nursing, or animals on medication. Sensitivities may occur after using ANY pesticide product for pets. If signs of sensitivity occur, bathe your pet with mild soap and rinse with large amounts of water. If signs continue, consult a veterinarian immediately. Some cats may be sensitive to products containing pyrethrins. Excessive salivation and ear and paw flicking may occur; however, these effects are temporary and not harmful. May cause dermal sensitization (skin allergy).

FIRST AID: Call a poison control center or doctor immediately for treatment advice.

If in eyes

● Hold eye open and rinse slowly and gently with water for 15-20 minutes.

● Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye.

If on skin or clothing

● Take off contaminated clothing.

● Rinse skin immediately with plenty of water for 15-20 minutes.

If swallowed

● Have person sip a glass of water if able to swallow.

● Do not induce vomiting unless told to do so by the poison control center or doctor.

● Do not give anything by mouth to an unconscious person.

Have the product container or label with you when calling a poison control center, doctor, or veterinarian or going for treatment. You may also contact 1-800-766-7661 for emergency medical treatment information.

PHYSICAL HAZARDS: Combustible. Do not use or store near heat or open flame.

For more information, or in case of emergency, call 1-800-766-7661.



In case of emergency or for product use information, call 1-800-766-7661.

Ovitrol Plus, Precor, Siphotrol, Vet-Kem and the Vet-Kem logo are registered trademarks of Wellmark International. All other trademarks are property of their respective owners.

Wellmark International, 1501 East Woodfield Road 200W, Schaumburg, Illinois 60173

EPA Reg. No. 2724-404

EPA Est. No. 2724-TX-1

©2001-2008, 2010 Wellmark International

Made in USA


Product Code:



1 PT (16 fl oz)





CPN: 1143086.1

Distributed by PRN PHARMACAL
Customer Service:   850-476-9462
Telephone:   850-478-2770
Order Desk:   800-874-9764
Every effort has been made to ensure the accuracy of the Vet-Kem Ovitrol Plus Flea, Tick & Bot Spray information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2019 Animalytix LLC. Updated: 2019-01-22