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Uniprim Oral Granules (Canada)

This page contains information on Uniprim Oral Granules for veterinary use.
The information provided typically includes the following:
  • Uniprim Oral Granules Indications
  • Warnings and cautions for Uniprim Oral Granules
  • Direction and dosage information for Uniprim Oral Granules

Uniprim Oral Granules

This treatment applies to the following species:
Manufacturer: Neogen


For Veterinary Use Only

DIN 02320835


UNIPRIM Oral Granules contains trimethoprim, a synthetic antibacterial, and sulfadiazine, a sulfonamide in combination at a ratio of 1:5. The two components of UNIPRIM produce a sequential blockade of bacterial metabolism, giving a level of activity many times greater than that obtained from either drug alone.

Dosage Form

UNIPRIM Oral Granules is a dosage form containing 6.7% w/w trimethoprim USP and 33.3% w/w sulfadiazine USP in an inert carrier.

Spectrum Of Activity

UNIPRIM provides effective antibacterial activity against a wide range of infections caused by Gram-positive and Gram-negative bacteria.

Pathogenic bacteria which can cause infection in the horse and are sensitive to UNIPRIM in vitro include:

Very sensitive organisms:

Escherichia coli, Salmonella spp., Haemophilus spp., Shigella equirulis, Pasteurella spp.

Sensitive organisms:

Streptococcus spp., Klebsiella spp., Corynebacterium spp., Actinobacillus spp., Staphylococcus spp. (including penicillinase-producing organisms), Proteus spp., Bordetella spp., Listeria monocytogenes

Non-sensitive organisms:

Pseudomonas aeruginosa*, Leptospira spp.

* usually non-sensitive

Uniprim Oral Granules Indications

UNIPRIM Oral Granules is indicated in horses for the treatment of the following infections when caused by susceptible organisms:

- Acute strangles

- Other respiratory infections

- Wound and postoperative infections

Uniprim Oral Granules Dosage And Administration

The usual dose of UNIPRIM Oral Granules for horses, ponies and foals is 3.75 g per 50 kg. The contents of one scoop (37.5 g) is sufficient to treat 500 kg liveweight. This dose provides 30 mg/kg bodyweight of actives daily.

The granules should be mixed with a small amount of palatable feed. UNIPRIM Oral Granules is palatable but if the treated horse does not consume the medication in toto, then parenteral or individual oral dosage with an alternative product should be considered.

Treatment should be given once daily until 2-3 days after the animal becomes asymptomatic. The usual course of treatment is for not longer than 7 consecutive days.


UNIPRIM Oral Granules should not be used in horses showing marked liver parenchymal damage or blood dyscrasias, nor in those with a history of sulfonamide sensitivity.

Adverse Reactions

No significant adverse reaction have been reported.

Uniprim Oral Granules Caution

UNIPRIM Oral Granules should not be administered to pregnant mares as the effects of this product when used as recommended, on the unborn foal have not been determined.


Treated animals must not be slaughtered for use in food for at least 7 days after the latest treatment with this drug.


Store between 2° and 35° C.


20 kg pail; 750 g and 262.5 g jars.

Distributed by: BIO AGRI MIX LP, PO Box 399, Mitchell, Ontario, Canada, N0K 1N0

NAC No.: 1269002.1

Distributed by BIO AGRI MIX LP
Telephone:   519-348-9865
Order Desk:   800-265-1763
Technical Information:   519-348-4402
Fax:   519-348-4100
Every effort has been made to ensure the accuracy of the Uniprim Oral Granules information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert.

Copyright © 2016 North American Compendiums. Updated: 2016-08-21