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Tetradure LA 300 (Canada)

This page contains information on Tetradure LA 300 for veterinary use.
The information provided typically includes the following:
  • Tetradure LA 300 Indications
  • Warnings and cautions for Tetradure LA 300
  • Direction and dosage information for Tetradure LA 300

Tetradure La 300

This treatment applies to the following species:
Manufacturer: Merial

Sterile Injectable Solution

(Oxytetracycline Dihydrate)

Veterinary Use Only

Din: 02184621


TETRADURE® LA 300 Injectable Solution is specially formulated to provide sustained antibiotic blood levels up to 4 days in cattle and pigs following a single treatment.

TETRADURE® LA 300 Injectable Solution is a sterile, long acting stable aqueous solution containing oxytetracycline dihydrate equivalent to 300 mg oxytetracycline base per ml.


TETRADURE® LA 300 Injectable Solution offers the advantage of combining broad spectrum effectiveness against both gram positive and gram negative bacteria, with prolonged antibiotic blood levels up to 4 days duration following a single treatment.

Tetradure LA 300 Indications

TETRADURE® LA 300 Injectable Solution is indicated in the treatment of all infections caused by oxytetracycline susceptible bacteria in cattle and pigs.

CATTLE: Bacterial pneumonia, Pasteurellosis (associated with shipping fever complex), Mastitis, Metritis, Calf Scours (bacterial enteritis), Foot Rot, Navel ill, Calf Diphtheria, Leptospirosis, Blackleg/Malignant Edema, Peritonitis, Joint ill.

SWINE: Erysipelas, Bacterial enteritis, Leptospirosis, Metritis, Mastitis, Bacterial pneumonia.

Tetradure LA 300 Dosage And Administration

For intramuscular or subcutaneous administration to cattle and intramuscular administration to pigs at a single dose rate of 1 mL per 15 kg of live bodyweight (20 mg oxytetracycline per kg bodyweight).

It is recommended that the maximum dose at any one site is 10 mL in cattle and 5 mL in pigs to minimize local tissue irritation at the injection site. Intramuscular injections should be made deep into the fleshy part of the muscle such as the neck. Subcutaneous injections should be administered in the neck region.

Following administration, temporary localised swelling may be observed at the site of injection for several days. This is due to the high concentration and long acting effect of the product.

TETRADURE® LA 300 Injectable Solution should be warmed to body temperature prior to administration.

If clinical improvement is not observed after 48 hours, clinical re-evaluation may be required. In non-responsive cases, consideration may be given to the use of an alternative antibiotic.


Treatment with Tetradure® LA 300 only, in severe disease cases, may be insufficient.


Intramuscular administration:

Treated animals must not be slaughtered for use in food for at least 21 days after the latest treatment with this drug. Do not use in lactating dairy cattle.

Subcutaneous administration:

Treated cattle must not be slaughtered for use in food for at least 42 days after the latest treatment with this drug. Do not use in lactating dairy cattle.


To avoid the possibility of excessive trim at the site of injection, do not slaughter cattle for at least 42 days after the latest treatment with this drug.

Tetradure LA 300 Caution

Occasional hypersensitivity reactions (anaphylaxis) have been observed following the parenteral administration of oxytetracycline. If such side effects occur, discontinue use of the drug and administer epinephrine immediately. The safety of this product in pregnant animals has not been demonstrated.


Store below 25°C. Protect from light.

Do not freeze.


TETRADURE® LA 300 Injectable Solution is available in multidose 250 mL and 500 mL vials.

Manufactured By

Norbrook Laboratories Limited, Newry, BT35 6JP, Northern Ireland

Distributed By

Merial Canada Inc., Baie d’Urfé, Québec H9X 4B6, Canada


Nac No.

Telephone:   514-457-1555
Order Desk:   888-637-4251 (888-MERIAL1)
Fax:   514-457-1175
Every effort has been made to ensure the accuracy of the Tetradure LA 300 information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert.

Copyright © 2018 North American Compendiums. Updated: 2018-05-30