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Tetanus Antitoxin (Canada)

This page contains information on Tetanus Antitoxin for veterinary use.
The information provided typically includes the following:
  • Tetanus Antitoxin Indications
  • Warnings and cautions for Tetanus Antitoxin
  • Direction and dosage information for Tetanus Antitoxin

Tetanus Antitoxin

This treatment applies to the following species:
Manufacturer: Zoetis

For Veterinary Use Only

Tetanus Antitoxin Indication

For use in domestic animals for prevention and treatment of tetanus.


This product is prepared from the blood of horses repeatedly injected with large doses of the toxin of Clostridium tetani.

Administration And Dosage

1500 units, minimum, if injected within 24 hours of exposure. Administer subcutaneously, intravenously or intraperitoneally. Increase dose relative to the lapse of time following exposure to as much as 30,000 to 100,000 units in animals which are showing symptoms. Massive initial doses may succeed in effecting a cure where repeated smaller doses of the same aggregate volume may have no value.

It should always be remembered that good nursing and proper supportive treatment, in addition to the administration of antitoxin, will improve the patient's chances for recovery.

Tetanus Antitoxin Caution

Store in the dark at 2° to 7°C (35° to 45°F). Avoid freezing. Use entire contents when first opened. Do not administer to food producing animals within 21 days before slaughter.

In case of anaphylactoid reaction, administer epinephrine.

Phenol and thimerosal added as preservatives.

It has been reported that biologicals of equine origin may in some manner be associated with the development of hepatitis (Theiler's disease)1,2 when injected into the equine species. The incidence of Theiler's disease is rare and in affected animals may be manifested as hepatitis, icterus, anorexia, emaciation and death.


1. Panciera, Roger J., D.V.M., Ph.D., “Serum Hepatitis in the Horse.” JAVMA, 155 (July 15, 1969) 408-410.

2. Rose, J.A., Immenschuh, R.D. and Rose, Ethel M., “Serum Hepatitis in the Horse.” Proc. 20th Ann. Conv. Am. Assoc. Equine Practice, December, 1974.

U.S. Veterinary License No. 190

Zoetis Inc., Kalamazoo, MI 49007, USA




Carton of 10 x 1,500 unit vials



NAC No.: 1198411.2

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Every effort has been made to ensure the accuracy of the Tetanus Antitoxin information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert.

Copyright © 2018 Animalytix LLC. Updated: 2018-11-30