Surmax 100 Premix (Canada)This page contains information on Surmax 100 Premix for veterinary use.
The information provided typically includes the following:
- Surmax 100 Premix Indications
- Warnings and cautions for Surmax 100 Premix
- Direction and dosage information for Surmax 100 Premix
Surmax 100 PremixThis treatment applies to the following species:
avilamycin premix 100 g/kg
FOR VETERINARY USE ONLY
FOR USE IN BROILER FEEDS ONLY
ACTIVE DRUG INGREDIENT:
100 g per kg premix
Avilamycin is an antibiotic of the orthosomycin family produced by fermentation of Streptomyces viridochromogenes. Orthosomycin antibiotics are divided into two groups: those that contain an aminocyclitol residue and those that are esters of dichlorisoeverninic acid. Avilamycin falls into the latter group as do the everninomicins.
Avilamycin inhibits bacterial protein synthesis through a novel mechanism of action by binding to the 50S ribosomal subunit and preventing the association of IF2, which inhibits the formation of the mature 70S initiation complex, and the correct positioning of tRNA in the aminoacyl site.
Avilamycin is primarily active against gram-positive bacteria. Its MIC range for Bacillus spp., Clostridium spp., Corynebacterium bovis, Enterococcus spp., Lactobacillus spp., Listeria monocytogenes, Micrococcus luteus, Staphylococcus aureus and Streptococcus spp. is 0.0125-1.6 µg/mL.
For the prevention of necrotic enteritis due by Clostridium perfringens in growing broiler chickens.
Note: Comprehensive necrotic enteritis management should be planned in consultation with veterinary and nutritional poultry expertise, and based on flock health history and exposure to necrotic enteritis risk factors.
DOSAGE AND ADMINISTRATION
Thoroughly mix 0.15 to 0.30 kg of Surmax 100 Premix per 1000 kg of feed to yield 15 to 30 ppm of Avilamycin.
IMPORTANT: Must be thoroughly mixed in broiler feed before use.
For better dispersion, it is recommended that Surmax 100 Premix be thoroughly mixed with a small quantity of the feed ingredients (totalling at least 10 kg) prior to the manufacturing of the medicated feed.
NOTE: Do not use in feeds containing pellet binding agents with the exception of calcium lignosulfate pellet binder.
Avilamycin should be fed as a sole ration continuously at 15 to 30 ppm for a period of 21days during the period of risk of necrotic enteritis, as determined by the veterinarian.
No preslaughter withdrawal periods are required for broiler chickens when treated according to the label.
Do not use in laying hens.
Avoid inhalation, oral exposure, and direct contact with skin or eyes. Operators mixing and handling Surmax 100 Premix should use protective clothing, impervious gloves, goggles, and an approved dust mask. Wash thoroughly with soap and water after handling. If accidental eye contact occurs, immediately rinse thoroughly with water. If irritation persists, seek medical attention.
Keep out of reach of children.
Store at or below 25°C.
Surmax, Elanco and the diagonal bar logo are trademarks of Eli Lilly and Company or affiliates.
Elanco Canada Limited, 150 Research Lane, Suite 120, Guelph, Ontario N1G 4T2
(successor to Novartis Animal Health Canada Inc.)
RESEARCH PARK CENTRE, 150 RESEARCH LANE, SUITE 120, GUELPH, ON, N1G 4T2
|Every effort has been made to ensure the accuracy of the Surmax 100 Premix information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert.|
Copyright © 2018 Animalytix LLC. Updated: 2018-10-31