Skip to Content

The originating document has been archived. We cannot confirm the completeness, accuracy and currency of the content.

Sow Bac TREC

This page contains information on Sow Bac TREC for veterinary use.
The information provided typically includes the following:
  • Sow Bac TREC Indications
  • Warnings and cautions for Sow Bac TREC
  • Direction and dosage information for Sow Bac TREC

Sow Bac Trec

This treatment applies to the following species:
Manufacturer: Intervet/Merck Animal Health

Porcine Rotavirus-transmissible Gastroenteritis Vaccine

Modified Live Virus

Bordetella bronchiseptica - clostridium perfringens type c - erysipelothrix rhusiopathiae - escherichia coli - pasteurella multocida Bacterin-toxoid



Porcine Rotavirus-Transmissible Gastroenteritis vaccine and Bordetella bronchiseptica-Clostridium perfringens Type C-Erysipelothrix rhusiopathiae-Escherichia coli-Pasteurella multocida bacterin-toxoid are used for the vaccination of healthy pregnant swine, to provide active protection against Erysipelothrix rhusiopathiae; and to provide sows and gilts with passive protection to their nursing pigs against 12 important pathogens:

1. Rotavirus (2 modified live G serotypes 5 and 4 of Serogroup A rotavirus).

2. TGE (transmissible gastroenteritis).

3. Atrophic rhinitis and pneumonia (Bordetella bronchiseptica and Pasteurella multocida non-toxigenic type A and toxigenic types A and D).

4. Colibacillosis (Escherichia coli pilus antigens K88, K99, F41 and 987P).

5. Enterotoxemia (Clostridium perfringens type C).

These etiologic agents are the most important causes of neonatal porcine diarrhea, atrophic rhinitis and pneumonia. They often occur in combination with each other causing increased morbidity and mortality losses. Furthermore, several of these diseases may produce similar clinical signs in baby pigs, therefore it is highly desirable to provide broad protection to nursing pigs. Laboratory confirmation of the cause of baby diarrhea is recommended since other viral, bacterial and coccidial agents also can cause similar disease signs.

Product Description

The Rotavirus-TGE vaccine (ProSystem® TGE/Rota) contains two modified live G serotypes 5 and 4 of Serogroup A rotavirus, and a modified live TGE virus, in desiccated form. The bacterin-toxoid diluent (Sow Bac® CE II) is an adjuvanted liquid product containing Bordetella bronchiseptica, Pasteurella multocida non-toxigenic type A and toxigenic type D, Erysipelothrix rhusiopathiae, 4 major E. coli pilus antigens - K88, K99, F41 and 987P, and Cl. perfringens type C toxoid. Each serial of Sow Bac® CE II bacterin-toxoid is demonstrated to be compatible (non-viricidal) and therefore can be used as a diluent when packaged with the viral vaccine.

Safety And Efficacy

Virus vaccination of the modified live rotaviruses and TGE have been demonstrated. The Rotavirus-TGE vaccine, rehydrated with the bacterin-toxoid, and the bacterin-toxoid alone have been evaluated for safety in pregnant swine as well as in laboratory animals. No adverse reactions were observed. Baby pigs are protected from enteritis, atrophic rhinitis, pneumonia, colibacillosis and enterotoxemia by receiving colostral and milk antibodies from vaccinated dams. Therefore it is mandatory that sows and gilts are lactating and baby pigs are nursing adequately.

Dosage Guidelines

Follow directions carefully. Two vaccination programs may be used.

Intramuscular (injection) Vaccination Method

to be used for sows and gilts having significant virulent TGE exposure within the prior 12 months.

1. Reconstitute ProSystem® TGE/Rota virus vaccine with Sow Bac® CE II bacterin-toxoid diluent, shake bacterin-toxoid well before and after addition to the virus vaccine.

2. Inject pregnant sow or gilt with 2.0 mL intramuscularly at 5 weeks and again at 2 weeks before each farrowing.

Oral And Intramuscular (oral) Vaccination Method

to be used for sows and gilts not previously exposed to virulent TGE.

1. For initial use, each pregnant sow or gilt must receive at least 2 oral and 1 intramuscular dosings of ProSystem® TGE/Rota virus vaccine and 2 doses of Sow Bac® CE II bacterin-toxoid before farrowing. Refer to the five-step method for oral vaccination, as shown below, using desiccated viral vaccine.

a. 5 weeks before farrowing - 1 oral dose ProSystem® TGE/Rota and 1 intramuscular dose of Sow Bac® CE II bacterin-toxoid.

b. 3 weeks before farrowing - 1 oral dose ProSystem® TGE/Rota.

c. 1 week before farrowing - 1 intramuscular dose of ProSystem® TGE/Rota rehydrated with Sow Bac® CE II bacterin-toxoid.

2. Subsequent farrowings - 2 weeks before farrowing, administer 1 oral dose of ProSystem® TGE/Rota and 1 intramuscular dose of ProSystem® TGE/Rota rehydrated with Sow Bac® CE II bacterin-toxoid.

For combination injection, reconstitute ProSystem® TGE/Rota dried vaccine with the accompanying Sow Bac® CE II bacterin-toxoid diluent. Shake well before use. If the bacterin-toxoid is given separately (e.g., at the time of oral vaccination with ProSystem® TGE/Rota), the 2.0 mL dose can be injected either intramuscularly or subcutaneously.

For best TGE protection, sows and gilts which have never been exposed to virulent TGE virus should be vaccinated following the oral vaccination guidelines (above) and their baby pigs should be orally vaccinated with ProSystem® TGE (Transmissible Gastroenteritis vaccine) following package insert guidelines.

Sow Bac TREC Caution

1. Store in the dark at not over 45°F (7°C). Do not freeze.

2. Use vaccine immediately after reconstitution. Use entire contents when first opened. Burn the container and all unused contents.

3. Use in healthy pregnant swine only, and do not vaccinate within 21 days of slaughter.

4. Conditions which interfere with lactation adversely affect immunity in baby pigs.

5. If allergic reaction follows use of this product, treat with epinephrine.

6. Although this product has been shown to be efficacious, some animals may be unable to develop or maintain an adequate immune response following vaccination if they are incubating any infectious disease, are malnourished or parasitized, or stressed due to shipment or adverse environmental conditions.

7. For highly TGE-susceptible (seronegative) sows and gilts, always use oral TGE vaccination program.

8. Contains gentamicin, polymyxin B and thimerosal as preservatives.


One 10-dose vial each of ProSystem® TGE/Rota and Sow Bac® CE II.

Recommended Methods For Oral Vaccination Of Swine

Step 1.

Pour approximately 2 to 2 1/2 gallons of cool water into a large plastic bucket. Add 5-10 cups of dry milk (any type of dry milk for human consumption is acceptable). Do not use hot water - it will destroy the vaccine.

Step 2.

Stir milk mixture well. Drywall paddles attached to 1/2” drill make mixing easier.

Step 3.

Remove metal ring and stopper. Reconstitute vaccine with diluent or milk; add reconstituted vaccine to milk, and stir.

Step 4.

Slowly add 40 lbs. of clean ground corn to the milk/vaccine mixture. Stir continuously, using an electric 1/2” drill and drywall paddle, until mixture thickens and drill pulls down. There should be no run-off seen. Mixing procedure takes approximately 3 minutes.

Step 5.

Feed to pregnant sows and gilts in one of two ways:

1. Feed sows individually with approximately 4 lbs. of milk/vaccine/corn mixture.

2. Spread milk/vaccine/corn mixture in a row onto concrete, feeding 10 sows at a time.

Intervet Inc., millsboro, Delaware U.s.a.

u.s. Veterinary License No. 165a

for Veterinary Use Only







10 doses

20 mL



Nac No.


556 MORRIS AVE., SUMMIT, NJ, 07901
Telephone:   862-245-4321
Order Desk:   800-648-2118
Fax:   862-245-4935
Customer Service:   800-521-5767
Every effort has been made to ensure the accuracy of the Sow Bac TREC information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2018 North American Compendiums. Updated: 2018-03-29