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This page contains information on Respira-1 for veterinary use.
The information provided typically includes the following:
  • Respira-1 Indications
  • Warnings and cautions for Respira-1
  • Direction and dosage information for Respira-1


This treatment applies to the following species:
Company: Colorado Serum

Modified Live Virus

General Information

This carton includes one bottle of freeze-dried Bovine Rhinotracheitis Vaccine and a second bottle of sterile diluent. When the modified-live virus vaccine is rehydrated with diluent, the resulting product may then be used to vaccinate healthy calves and non-pregnant cattle. For use as an aid in the prevention of infectious bovine rhinotracheitis caused by infectious bovine rhinotracheitis (IBR) virus.

IBR may be confused with other viral diseases commonly found in feed lot cattle. This must be taken into consideration when planning an effective vaccination program.

Bovine rhinotracheitis, sometimes referred to as “Red Nose” or “Rhino”, is caused by IBR virus which attacts the upper respiratory tract (trachea, mucous membranes, and larynx) of exposed cattle. Salivation, congestion of the nasal mucosa, serous nasal discharge, rapid respiration, coughing, and depression, are some of the clinical signs frequently observed. Temperatures may vary from a little above the normal temperature range of 100.5-102.5° F (38-39°C) to as high as 108° F (42°C). High morbidity with low mortality is the usual pattern. The most serious economic factor in the feed lot is the substantial weight loss of affected animals. In dairy cows milk production may be reduced or eliminated as a result of IBR virus infection.

Usually the disease appears three or more weeks after calves are in corrals, progressing toward full feed and beginning to take on considerable flesh. Outbreaks may also appear in beef cattle in prime condition and almost ready for market. Weight loss in these instances is very costly. The number of affected animals in any feed lot group can be quite variable. This disease does not respond well to supportive therapy. Prevention is the only practical way to avoid the losses that accompany outbreaks. Regular use of Bovine Rhinotracheitis Vaccine is beneficial and considered to be good practice when used according to directions.


Cattle should be vaccinated before or when entering feedlots or areas where dairies are located.

Do not administer to pregnant cows or calves nursing pregnant cows. Do not administer to calves less than 4 weeks of age. Maternal antibodies in young calves may interfere with development of active immunity. For this reason, calves vaccinated before the age of 6 months should be revaccinated after 6 months of age.

Yearly booster injections are recommended for breeding stock. Be sure that breeding stock are vaccinated on a regular basis when cows are open.

Do not vaccinate within 21 days before slaughter. Needle punctures and tissue damage at the site of injection may result in condemnation of carcasses.


Anaphylactoid reaction may occur following administration of products of this nature. If noted, administer adrenalin or equivalent.

Packaged in 10 dose (20 mL) and 50 dose (100 mL) sizes.

U.S. Veterinary License No. 188


4950 York Street - P.O. Box 16428

Denver, Colorado 80216

CODE 1101.00

CPN: 11010362

4950 YORK STREET, P.O. BOX 16428, DENVER, CO, 80216-0428
Telephone:   303-295-7527
Order Desk:   800-525-2065
Fax:   303-295-1923
Every effort has been made to ensure the accuracy of the Respira-1 information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

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