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PM-Onevax

This page contains information on PM-Onevax for veterinary use.
The information provided typically includes the following:
  • PM-Onevax Indications
  • Warnings and cautions for PM-Onevax
  • Direction and dosage information for PM-Onevax

PM-Onevax

This treatment applies to the following species:
Manufacturer: Intervet/Merck Animal Health

Pasteurella Multocida Vaccine

Avirulent Live Culture, Avian Isolate

DIRECTIONS FOR USE, READ CAREFULLY

PM-ONEVAX vaccine is a live bacterial vaccine containing the mild avirulent PM-1 strain of Pasteurella multocida in a freeze-dried preparation sealed under vacuum. The seed culture used to make this vaccine has been laboratory tested for protection in chickens against challenge with the P1059 (Type 3) strain of P. multocida.

For use in healthy turkeys 6 weeks of age or older as an aid in preventing pasteurellosis (fowl cholera) due to Pasteurella multocida Type 3, through vaccination by the drinking water method.

WHEN TO VACCINATE

Best results are obtained when vaccine is administered initially to turkeys 6 to 8 weeks of age and repeated every 4 to 6 weeks thereafter as necessary according to exposure conditions.

YOUR VACCINATION PROGRAM

The development of a durable, strong protection to this disease depends upon the use of an effective vaccination program as well as many circumstances such as administration techniques, environment and flock health at the time of vaccination. Also, the immune response to one vaccination under field conditions is seldom complete for all animals within a given flock. Even when vaccination is successful, the protection stimulated in individual animals against different diseases may not be life long. Therefore, a program of periodic revaccination may be necessary.

CONTRAINDICATIONS

Turkeys must be healthy and free of environmental or physical stress at the time of vaccination. Initial vaccination with this vaccine should not be conducted in turkeys older than 12 weeks of age. Do not use this vaccine within 2 weeks before or 2 weeks after vaccinating turkeys with live virus Newcastle vaccine.

PREPARATION OF THE VACCINE

1. Assemble the vaccine and equipment needed to vaccinate the entire flock at one time.

2. Do not open and rehydrate the vaccine until ready for use.

3. Remove the tear-off aluminum seal from the vaccine vial without disturbing the rubber stopper.

4. Use cool, clean, nonchlorinated tap water to which powdered milk has been added as directed under How to Vaccinate.

5. Remove the rubber stopper from the vaccine vial and rehydrate the vaccine by filling the vial about half-full with tap water (milk added).

6. Reseat the stopper and shake to thoroughly dissolve the vaccine.

HOW TO VACCINATE

Do not mix the vaccine into the drinking water until ready for use. Drinking water for vaccination should be mixed with powdered milk to prevent inactivation from chlorine or other water additives and also to stabilize the vaccine bacteria. The powdered milk should be added to the water at the rate of 3 grams per 11 liters (one heaped teaspoon per 3 U.S. gallons or 2.5 Imp. gallons); or 90 grams per 300 liters (one heaped cupful per 80 U.S. gallons or 66 Imp. gallons).

Use only clean waterers and equipment free of disinfectants or sanitizers. All water must be withheld for at least 2 hours prior to vaccination to assure that all turkeys drink. Mix the rehydrated vaccine in the quantity of drinking water (milk added) which will be consumed by thirsty turkeys in approximately 2 hours.

The following schedule is a general guideline for the amount of water to use with the vaccine. These amounts will vary depending upon the individual management conditions, climate, age and sex of the birds.

Age

Sex

Climate

Amount of Water For Each 1000 Doses

L.

U.S. gal.

Imp. gal.

6-8 Wks.

Toms

Hot

95

25

21

6-8 Wks.

Hens

Hot

76

20

17

6-8 Wks.

Toms

Cold

49

13

11

6-8 Wks.

Hens

Cold

38

10

8

10-14 Wks.

Toms

Hot

133

35

29

10-14 Wks.

Hens

Hot

103

27

22

10-14 Wks.

Toms

Cold

68

18

15

10-14 Wks.

Hens

Cold

53

14

12

Another helpful guideline for daily water consumption is 3.8 liters (one U.S. gallon or 0.8 Imp. gallon) of water per week of age per 100 poults; figure 40% of this amount. This 40% is about a 3 hour supply for the flock.

Distribute 1000 doses of vaccine in water as used by 1000 turkeys. Provide ample water space so that all turkeys can drink easily. Do not administer through water lines with a proportioner or medication tank.

CAUTION

1. For veterinary use only.

2. To avoid interference with development of protection, turkeys to be vaccinated should not be given any antibiotic and/or sulfonamide medication used in the prevention or treatment of fowl cholera for 3 days before and 5 days after vaccination.

3. Vaccinate only healthy birds. Coccidiosis, respiratory disease, mycoplasma infection, or other disease conditions may cause serious complications or reduce protection. Vaccinated flocks should be watched closely and medicated as necessary to control more severe reactions. Avoid exposing birds other than turkeys to this vaccine.

4. All birds within a flock should be vaccinated on the same day. Isolate other susceptible birds on the premises from the birds being vaccinated.

5. In outbreak situations, vaccinate healthy birds first progressing toward outbreak areas in order to vaccinate affected birds last. Vaccination in the face of an acute outbreak is not recommended. Under these conditions, use an effective fowl cholera treatment, wait at least 3 days or until the outbreak subsides, and then vaccinate.

6. Do not spill or spatter the vaccine. Burn empty bottles, caps and all unused vaccine and accessories. Use entire contents of vial when first opened.

7. Wash hands thoroughly after using the vaccine.

8. Do not dilute the vaccine or otherwise stretch the dosage.

9. Store at 2° to 7° C (35° to 45° F).

10. Do not vaccinate within 21 days of slaughter.

RECORDS

Keep a record of vaccine type, quantity, serial number, expiration date, and place of purchase; the date and time of vaccination; the number, age, breed, and location of the birds; names of operators performing the vaccination and any observed reactions.

U.S. FEDERAL REGULATIONS PROHIBIT REPACKAGING OR SALE OF THE CONTENTS OF THIS CARTON IN FRACTIONAL UNITS. DO NOT ACCEPT IF SEAL IS BROKEN.

U.S. Veterinary License No. 165A

Schering-Plough Animal Health Corp, Omaha, Nebraska 68103, USA

1 800 219-9286 (USA)

1 888 306-0069 (Canada)

© 1990, 1992, 2002 Schering-Plough Animal Health

All rights reserved.

Made in USA

® Registered Trademark

P17202-13

 

NDC-

 

10 x 1000 Doses

0138-0832-01

P17207-13

NAC No.: 10471572

MERCK ANIMAL HEALTH
Intervet Inc.

2 GIRALDA FARMS, MADISON, NJ, 07940
Customer Service:   800-521-5767
Order Desk:   800-648-2118
Technical Service (Companion Animal):   800-224-5318
Technical Service (Livestock):   800-211-3573
Fax:   973-937-5557
Website:   www.merck-animal-health-usa.com
Every effort has been made to ensure the accuracy of the PM-Onevax information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2016 North American Compendiums. Updated: 2016-10-31

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