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Phenylbute Paste

This page contains information on Phenylbute Paste for veterinary use.
The information provided typically includes the following:
  • Phenylbute Paste Indications
  • Warnings and cautions for Phenylbute Paste
  • Direction and dosage information for Phenylbute Paste

Phenylbute Paste

This treatment applies to the following species:
Company: Clipper (Phoenix Pharm.)


for Horses

ANADA 200-266, Approved by the FDA.

For Veterinary Use Only

Each 3 mL marking on the plunger contains:


1 g.


Phenylbutazone Paste is a synthetic, nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound’s anti-inflammatory properties.

Chemically, Phenylbutazone Paste is 4-butyl-1, 2-diphenyl-3,5-pyrazolidinedione. It is a pyrazolone derivative, entirely unrelated to the steroid hormones.

Phenylbute Paste Indications

For the relief of inflammatory conditions associated with the musculoskeletal system in horses.


Use with caution in patients who have a history of drug allergy.

WARNING: Not for use in horses intended for food.


Stop medication at the first sign of gastrointestinal upset, jaundice, or blood dyscrasia. Authenticated cases of agranulocytosis associated with the drug have occurred in man; fatal reactions, although rare, have been reported in dogs after long-term therapy. To guard against this possibility, conduct routine blood counts at weekly intervals during the early phase of therapy and at intervals of two weeks thereafter. Any significant fall in the total white count, relative decrease in granulocytes, or black or tarry stools, should be regarded as a signal for immediate cessation of therapy and institution of appropriate counter measures. In the treatment of inflammatory conditions associated with infections, specific anti-infective therapy is required.

ADMINISTRATION AND DOSAGE: Orally - 1 to 2 g of phenylbutazone per 500 lb. of body weight daily. Do not exceed 4 g daily.

Guidelines to Successful Therapy: Use a relatively high dose for the first 48 hours, then reduce gradually to a maintenance dose. Maintain lowest dose capable of producing desired clinical response. Response to Phenylbutazone Paste therapy is prompt, usually occurring within 24 hours. If no significant clinical effect is evident after five days, re-evaluate diagnosis and therapeutic approach. When administering Phenylbutazone Paste, the oral cavity should be empty. Deposit paste on back of tongue by depressing plunger that has been previously set to deliver the correct dose. Many chronic conditions will respond to Phenylbutazone Paste therapy, but discontinuance of treatment may result in reoccurrence of symptoms.


Store at 15°-30°C (59°-86°F).

How Supplied

Syringes containing 20 g of phenylbutazone.


Phenylbute Paste Caution

Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian.

Manufactured by: Med-Pharmex, Inc., Pomona, CA 91767-1861


Trademarks are property of Clipper Distributing Company, LLC

Manufactured For: Clipper Distributing Company LLC, St. Joseph, MO USA

rev 01/12

Net Volume:


60 mL


CPN: 12560643


1302 SOUTH 59 STREET, ST. JOSEPH, MO, 64507
Telephone:   816-364-5777
Order Desk:   800-759-3644
THIS SERVICE AND DATA ARE PROVIDED "AS IS". DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. See the Terms of Use for further details.

Copyright © 2023 Animalytix LLC. Updated: 2023-11-27