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Pen Aqueous (Canada)

This page contains information on Pen Aqueous for veterinary use.
The information provided typically includes the following:
  • Pen Aqueous Indications
  • Warnings and cautions for Pen Aqueous
  • Direction and dosage information for Pen Aqueous

Pen Aqueous

This treatment applies to the following species:
Manufacturer: Zoetis

Penicillin G procaine injectable suspension Mfr. Std.

Veterinary Use Only


DIN 00712981

Active Ingredients/mL:

Procaine Penicillin G

300,000 IU


Methylparaben Sodium

0.11% w/v

Ethylparaben Sodium

0.02% w/v

Propylparaben Sodium

0.02% w/v

Pen Aqueous Indications

An antibiotic as an aid in the treatment of the following infections caused by bacteria susceptible to penicillin:

Cattle: Bacterial pneumonia, calf diphtheria, foot rot, metritis, wound infections.

Sheep: Bacterial pneumonia, metritis, wound infections.

Swine: Bacterial pneumonia, erysipelas, wound infections.

Horses: Bacterial pneumonia, metritis, strangles, wound infections.


Cattle and Sheep: 21,000 IU/kg (7 mL/100 kg) IM. Maximum injection volume: 15 mL per site in cattle, 5 mL for sheep.

Swine: 15,000 IU/kg (1 mL/20 kg) IM. Do not exceed 10 mL per injection site.

Administration: For cattle, sheep and swine: Administer once daily until 2 days after clinical signs disappear. Do not exceed 5 days of treatment.

Horses: 21,000 IU/kg (7 mL/100 kg) IM every 12 hours until 2 days after clinical signs disappear or, in case of respiratory infections, 5 days after clinical signs disappear. Do not exceed 15 mL per injection site. Rotate injection sites for subsequent doses.

Note: If no response is seen within 48 hours, consult a veterinarian and consider alternative therapy.

Cautions: In case of anaphylactic reaction (acute respiratory distress, mouth breathing, recumbency), administer epinephrine immediately to prevent death.

In pigs: occasionally this product causes fever, vomiting, shivering, listlessness, incoordination and possibly, death. May result in abortions in pregnant sows and gilts.

In horses: occasionally this product may cause excitement and pain at the injection site. Repeated use of the same injection site may intensify these effects.


Treated cattle and sheep must not be slaughtered for use in food for at least 10 days after the latest treatment with this drug.

Treated swine must not be slaughtered for use in food for at least 8 days after the latest treatment with this drug. Do not administer to horses that are to be slaughtered for use as food. Milk taken from treated animals during treatment and within 96 hours after the latest treatment must not be used as food.

To avoid illegal residues do not inject SC. Do not use in dairy animals with clinical or subclinical mastitis and do not exceed the recommended dosage.

The use of on-farm tests for detecting subclinical mastitis prior to treatment (C.M.T. or other tests) and/or detecting residues prior to marketing milk from treated animals is recommended.


Store below 25°C. Do not freeze.

Zoetis is a trademark of Zoetis or its licensors, used under license by Zoetis Canada Inc.

Zoetis Canada Inc., Kirkland QC H9H 4M7



250 mL



500 mL



NAC No.: 1198395.3

Order Desk:   800-663-8888
Technical Services Canada:   800-461-0917
Technical Services USA:   800-366-5288
Every effort has been made to ensure the accuracy of the Pen Aqueous information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert.

Copyright © 2017 North American Compendiums. Updated: 2017-11-28