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Neomycin 325

This page contains information on Neomycin 325 for veterinary use.
The information provided typically includes the following:
  • Neomycin 325 Indications
  • Warnings and cautions for Neomycin 325
  • Direction and dosage information for Neomycin 325

Neomycin 325

This treatment applies to the following species:
Manufacturer: Durvet

Soluble Powder

Neomycin Sulfate (commercial Grade)


For the treatment and control of colibacillosis (bacterial enteritis) caused by Escherichia coli susceptible to neomycin sulfate in cattle (excluding veal calves), swine, sheep and goats. For the control of mortality associated with Escherichia coli organisms susceptible to neomycin sulfate in growing turkeys.

Each Packet Contains

71.4 g neomycin sulfate (commercial grade) equivalent to 50 g neomycin.

For Animal Use Only

Keep Out Of Reach Of Children

ANADA 200-050, Approved By FDA

Restricted Drug - Use Only As Directed (california)

Add to drinking water - Not for use in liquid supplements.

Neomycin 325 Dosage And Administration

Administer to cattle (excluding veal calves), swine, sheep and goats at a dose of 10 mg neomycin sulfate per pound of body weight per day in divided doses for a maximum of 14 days. Administer to turkeys at a dose of 10 mg neomycin sulfate per pound of body weight per day for 5 days.

Herd/flock Treatment

Each packet will treat 7150 pounds body weight. Therefore, estimate the total number of pounds of body weight of the animals to be treated and administer one (1) packet (or portion thereof) for each 7150 pounds. The product should be added to the amount of drinking water estimated to be consumed in 12-24 hours. Provide medicated water as the sole source of water each day until consumed, followed by non-medicated water as required. Fresh medicated water should be prepared each day.

Individual Animal Treatment

To provide 10 mg neomycin sulfate per pound of body weight, mix one (1) level teaspoon* in water or milk for each 160 pounds body weight. Administer daily either as a drench in divided doses or in the drinking water to be consumed in 12-24 hours.

Drinking Water

Swine - Use the number of packets indicated below in 256 gallons of water, or in two gallons of stock solution used in proportioner set to meter one ounce per gallon.

Pigs Weighing 25 to 50 Pounds

2 Packets

Pigs Weighing 50 to 100 Pounds

3 Packets

Pigs Weighing Over 100 Pounds

4 Packets


To administer the stated dosage, the concentration of neomycin required in medicated water must be adjusted to compensate for variation in age and weight of animal, the nature and severity of disease signs, and environmental temperature and humidity, each of which affects water consumption.

If symptoms persist after using this preparation for 2 or 3 days, consult a veterinarian. If symptoms such as fever, depression, or going off feed develop, oral neomycin is not indicated as the sole treatment since systemic levels of neomycin are not obtained due to low absorption from the gastrointestinal tract.


Treatment should continue 24 to 48 hours beyond remission of disease symptoms, but not to exceed a total of 14 consecutive days for cattle, swine, sheep and goats and 5 days for turkeys. Animals not drinking or eating should be treated individually by drench.

Residue Warnings

Discontinue treatment prior to slaughter by at least the number of days listed below for appropriate species:

Cattle - 1 day, Swine and goats - 3 days, Sheep - 2 days, Turkeys - 0 days

A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.

A milk discard period has not been established for this product in lactating dairy cattle. Do not use in female dairy cattle 20 months of age or older.

Use of more than one product containing neomycin or failure to follow withdrawal times may result in illegal drug residues.

*Level Tablespoonful = US Standard Measure

Fold opened packet tightly to keep out moisture.

Store At Controlled Room Temperature.

Manufactured for: DURVET, INC., Blue Springs, Missouri 64014





100 Grams (3.5 Ounces)




Rev. 2/09

Nac No.

Telephone:   816-229-9101
Toll-Free:   800-821-5570
Fax:   816-224-3080
Every effort has been made to ensure the accuracy of the Neomycin 325 information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2018 North American Compendiums. Updated: 2018-04-26