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Multimune M

This page contains information on Multimune M for veterinary use.
The information provided typically includes the following:
  • Multimune M Indications
  • Warnings and cautions for Multimune M
  • Direction and dosage information for Multimune M

Multimune M

This treatment applies to the following species:
Manufacturer: Ceva Biomune

Pasteurella Multocida Vaccine, Avirulent Live Culture, Avian Isolate

U.S. Vet. Lic. No.: 368

Active Ingredient(s): MULTIMUNE® M is a live bacterial vaccine containing the avirulent M-9 strain of Pasteurella multocida in a freeze-dried preparation. The M-9 strain has been shown to offer protection against naturally occurring field strains of P. multocida. The seed culture used to make the vaccine has been laboratory tested as required by the USDA for protection against challenge with P. multocida strains P-1059 (type 3) and P-1662 (type 4).

Multimune M Indications

MULTIMUNE® M is recommended for use in healthy turkeys six weeks of age or older as an aid in preventing pasteurellosis (fowl cholera) due to Pasteurella multocida types 3 and 4.

Dosage and Administration

The contents of one vial of vaccine is administered to 1,000 turkeys by wing web stab (0.01 mL). The best results are obtained when the vaccine is administered initially to turkeys 6 to 12 weeks of age and repeated as needed according to current flock conditions. High disease challenge situations may require revaccination every 4 to 6 weeks.

Vaccinate healthy turkeys only. The initial vaccination should not be conducted in turkeys older than 12 weeks of age, as it may result in larger granulomas at the site of inoculation which may cause possible carcass downgrading at slaughter.

Rehydrate the vaccine vial with the entire contents of one (1) 10 mL vial of diluent (packaged separately) and mix well. Use the entire contents of one (1) 1,000 dose vial of vaccine within two (2) hours. Vaccinate by dipping the applicator needle into the rehydrated vaccine and piercing the webbed portion under the wing. Do not let the needle contact the feathers as they will absorb the vaccine preventing the turkey from receiving an adequate dose. Avoid piercing the wing muscle, bone or large blood vessels. Refill the needle between each vaccination by dipping the needle into the vial.

Usually there is not a clinical reaction to the vaccine. Vaccination sites should be examined five (5) to 10 days after vaccination for the presence of a reaction which is a small granuloma referred to as a vaccine “take”. If a reaction is not seen, the birds may have already been immune or the vaccination may not have been properly conducted.

Precaution(s): Keep MULTIMUNE® M vaccine refrigerated until use. Store the vaccine between 35°-45°F (2°-7°C).

Caution(s): Turkeys to be vaccinated should not be given any antibiotic and/or sulfonamide medication for three days before and five days after vaccination to avoid interference with vaccine immunity. Avoid vaccination with live Newcastle vaccine two weeks before and two weeks after vaccination with MULTIMUNE® M.

Since MULTIMUNE® M is a live bacterial culture, caution should be used to avoid contact with open wounds or accidental inoculation of personnel. If accidental inoculation occurs, consult a physician immediately as the vaccine may act as a human pathogen. Vaccinating crew personnel must wash their hands after using the vaccine.

Use the entire contents of the vial when first opened. Burn all unused contents.

Warning(s): Do not vaccinate within 21 days before slaughter.

Presentation: 10 x 1,000 dose vials of vaccine per box and 10 x 10 mL vials of diluent with vaccine applicators per box.

NAC No.: 11290182

Telephone:   913-894-0230
Fax:   913-894-0236
Every effort has been made to ensure the accuracy of the Multimune M information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2018 Animalytix LLC. Updated: 2018-10-31