Gentocin Ophthalmic OintmentThis page contains information on Gentocin Ophthalmic Ointment for veterinary use.
The information provided typically includes the following:
- Gentocin Ophthalmic Ointment Indications
- Warnings and cautions for Gentocin Ophthalmic Ointment
- Direction and dosage information for Gentocin Ophthalmic Ointment
Gentocin Ophthalmic OintmentThis treatment applies to the following species:
For use in dogs and cats.
ANADA 200-273 Approved by FDA.
Gentamicin sulfate is a water soluble antibiotic of the aminoglycoside group active against a wide variety of pathogenic gram-negative and gram-positive bacteria.
Gentocin® Ophthalmic Solution is a sterile ointment, each gram containing gentamicin sulfate (equivalent to 3 mg gentamicin) in a base of mineral oil and white petrolatum.
CHEMISTRY: Gentamicin sulfate is an aminoglycoside antibiotic mixture derived from Micromonospora purpurea of the Actinomycetes group. It is a powder, white to buff in color, readily soluble in water, and heat stable.
ACTION: Gentamicin sulfate, a broad spectrum antibiotic, is a highly effective topical treatment in primary and secondary bacterial infections of the eye and surrounding tissues. Gentamicin is bactericidal in vitro against a wide variety of gram-positive and gram-negative bacteria. Concentrations of gentamicin sulfate required to inhibit growth of gram-positive and gram-negative clinical and laboratory strains of bacteria tested were less than those of neomycin in most instances.1,2 Gentamicin is active against most gram-negative bacteria including Pseudomonas aeruginosa, indole positive and negative Proteus species, Escherichia coli, Klebsiella sp. and Enterobacter sp. Gentamicin is also active against strains of gram-positive bacteria including Staphylococcus species and Streptococcus species.
Gentocin Ophthalmic Ointment Indications
Gentocin® Ophthalmic Ointment are indicated for topical treatment of conjunctivitis caused by susceptible bacteria in dogs and cats.
Dosage and AdministrationApply approximately 1/2 inch strip of Gentocin® Ophthalmic Ointment to the affected eye(s) 2 to 4 times a day.
PrecautionsAntibiotic susceptibility of infecting organisms should be determined prior to the use of these preparations. Prolonged use of topical antibiotics may give rise to overgrowth of nonsusceptible organisms such as fungi. Should this occur or if irritation or hypersensitivity to any component develops, discontinue use of the preparation and institute appropriate therapy. Ophthalmic ointments may retard corneal healing.
Gentocin Ophthalmic Ointment Caution
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
How SuppliedGentocin® Ophthalmic Ointment is supplied in 3.5 g (1/8 oz) sterile tamper-proof tubes.
3.5 gram tube
Store between 2°-30°C (36°-86°F).
Manufactured for: Schering-Plough Animal Health Corporation, Summit, N.J. 07901
by Altana Inc., Melville, NY 11747
1. Weinstein MJ, Luedemann GM, Oden EM, Wagman GH. Gentamicin, a new broad spectrum antibiotic complex. Antimicrob. Agents and Chemother. 1963:1-7.
2. Black J, et al. Pharmacology of Gentamicin: a new broad spectrum antibiotic. Antimicrob. Agents and Chemother. 1964:138-147.
NAC No.: 10471001
2 GIRALDA FARMS, MADISON, NJ, 07940
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Copyright © 2018 North American Compendiums. Updated: 2018-04-26