Encephalomyelitis Vaccine Eastern & Western with Tetanus ToxoidThis page contains information on Encephalomyelitis Vaccine Eastern & Western with Tetanus Toxoid for veterinary use.
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- Encephalomyelitis Vaccine Eastern & Western with Tetanus Toxoid Indications
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Encephalomyelitis Vaccine Eastern & Western with Tetanus ToxoidThis treatment applies to the following species:
Encephalomyelitis Vaccine, Eastern & Western, Killed Virus-Tetanus Toxoid
U.S. Vet. Lic. No.: 188
Contents: This is a combination of three immunizing substances (listed above) that are commonly used in equines.
Contains thimerosal, penicillin, and streptomycin as preservatives.
Encephalomyelitis Vaccine Eastern & Western with Tetanus Toxoid Indications
When administered as directed this single product provides protection against Eastern and Western types of encephalomyelitis and against tetanus.
Dosage and AdministrationShake well prior to withdrawal from the bottle. Inject 2 mL deep in the muscle. Repeat in 3 to 4 weeks. A booster dose of 2 mL should be administered annually and whenever an epidemic situation develops and exposure is likely.
Precaution(s): Store in dark at 2° to 7°C.
Sterilize needles and syringes before using.
Use entire contents when bottle is first opened.
Caution(s): Transitory local reaction may appear at site of injection.
Anaphylaxis (shock) may sometimes follow use of products of this nature. Adrenalin, or equivalent should be available for immediate use in these instances.
Shake the product well before withdrawing. Each dose must have proportionate share of precipitate for proper response.
Warning(s): Meat animals should not be vaccinated within 21 days before slaughter.
For veterinary use only.
Discussion: Encephalomyelitis is often referred to as horse encephalitis (inflammation of the brain), sleeping sickness, blind staggers, and brain fever. It has occurred in nearly all parts of the United States, Canada, Mexico, Central America, and South America.
The first indication of equine encephalomyelitis is fever. Temperature will vary from 102° to 107°F. Sluggishness and drowsiness are early symptoms. Lips are loose and muscles around the head, shoulder or flank may twitch spasmodically. As the disease progresses the affected animal stands dejectedly and will move with an awkward staggering gait, oftentimes stumbling blindly into obstructions. Legs are frequently crossed. Some horses may back up persistently. When aroused the animal may show interest in food or water only to lapse into a stupor with unchewed food in its mouth. Grinding of the teeth and stretching the head and neck are common.
Tetanus is caused by a toxin (poison) produced by growth of Clostridium tetani, an anaerobic (lives without air) micro-organism that may be carried into wounds caused by injury or sites of surgical operations.
Affected animals become stiff, have great difficulty swallowing and the pulse rate is increased. Breathing is labored. Spasmodic contractions of the muscular system occurs, extending muscles of the jaw. Thus, the term “lockjaw” is frequently applied. Legs are often spread, tail stiff with abdominal muscles retracted. Tetanus stricken animals may be unusually sensitive to light and heat. Temperature of the animal generally remains normal, elevating only shortly before death.
The Vaccine fraction of this combination is prepared with formalin inactivated cultures of two antigenically different strains of encephalomyelitis virus which are identified as “Eastern” and “Western”. Diseases caused by the two types are clinically indistinguishable. Horses vaccinated with vaccine containing a single virus type are not immune to the other. Similarly, an animal that has recovered from infection caused by one type of virus is not protected from disease that may be caused by the other.
The tetanus toxoid fraction is prepared by detoxifying toxin with formalin and moderate heat in such manner that antigenic properties remain intact. The toxoid is refined to remove most of the nonspecific components and is concentrated to provide a low dose effective product for combination with Encephalomyelitis Vaccine fraction.
When to Vaccinate: Encephalomyelitis is spread by mosquitos and perhaps other biting insects so animals should be vaccinated prior to the time insects become prevalent. The Vaccine-Toxoid may also be used in the event of injury to equines. If a previously immunized animal is injured a booster dose of this combination of Tetanus Toxoid should be administered. If not previously immunized or if the injury occurs within 60 days of primary immunization Tetanus Antitoxin should be used simultaneously with this Vaccine-Toxoid or with Tetanus Toxoid alone.
Presentation: 10 x 2 mL and 20 mL vials.
NAC No.: 11010210
4950 YORK STREET, P.O. BOX 16428, DENVER, CO, 80216-0428
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Copyright © 2018 North American Compendiums. Updated: 2018-08-01