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Econiche (Canada)

This page contains information on Econiche for veterinary use.
The information provided typically includes the following:
  • Econiche Indications
  • Warnings and cautions for Econiche
  • Direction and dosage information for Econiche


This treatment applies to the following species:
Manufacturer: Bioniche Animal Health

Escherichia coli O157 Bacterial Extract Vaccine

For Veterinary Use Only

Cattle are considered the primary reservoir of Escherichia coli O157:H7 (Jackson et al. 1998). According to Health Canada, E. coli O157:H7, which secretes potent verotoxins, causes abdominal pain, bloody diarrhea and Haemolytic Uremic Syndrome (HUS) in humans. Approximately 2%-7% of human E. coli O157 infections result in HUS and death occurs in 1%-2% of the cases.

Econiche® is to be used as part of a comprehensive herd management program to reduce and

eliminate potential sources of E. coli O157:H7 contamination. Many factors influence E. coli O157:H7 prevalence in cattle, including geographic location, season of year, temperature, amount of rainfall, and pen condition (wet or dry) (Smith et al. 2005). Changes to animal and facility management practices concerning feed storage, feeding and watering practices, cattle mixing, manure handling, and the cleaning of equipment, pens and trucks, may also influence the prevalence of this and other microorganisms.

INDICATION: For vaccination of healthy cattle, 4 months of age or older, as an aid in the reduction of shedding of Escherichia coli O157.

Dosage and Administration

Inject 2 mL subcutaneously. Administer 3 doses 3 weeks apart.

Econiche Caution

Store at 2-7°C (36-45°F). Avoid freezing. Shake well. Use entire contents when first

opened. Vaccination may cause transient injection site swelling; in some animals this may persist for several weeks. In the event of anaphylaxis, administer epinephrine. Contains gentamycin as a preservative.


Do not vaccinate within 60 days of slaughter.

HUMAN SAFETY INFORMATION: Not for human use. Exercise caution to avoid accidental self-injection. In case of human injection, consult a physician immediately.

Proper Injectable Handling Procedures

1] Store in a safe location

2] Read, understand and follow all label use directions

3] For subcutaneous use in cattle

4] Properly restrain animals prior to administering vaccine

5] Keep a protective cover on needles until ready to use

6] Never carry loaded syringe in pocket or clothing

7] To minimize risk of self-injection with vaccine gun, ensure animals are properly restrained and that gun is not allowed to hang freely while handling animals.

PRESENTATION: 25, 50 and 125 dose vials.

Manufactured by: Bioniche Life Sciences Inc., P.O. Box 1570, Belleville, Ontario K8N 5J2

Canadian Veterinary Biologics Establishment License No. 8

Smith, D.R., R.A. Moxley, S.L. Clowser, J.D. Folmer, S. Hinkley, G.E. Erickson, T.J. Klopfenstein. 2005. Use of rope-devices to describe and explain the feedlot ecology of Escherichia coli O157:H7 by time and place. Foodborne Pathog Dis. 2(1):50-60.

Jackson, S.G., R.B. Goodbrand, R.P. Johnson, V.G. Odorico, D. Alves, K. Rahn, J.B. Wilson, M.K. Welch, R. Khakhria. 1998. Escherichia coli O157:H7 diarrhoea associated with well water and infected cattle on an Ontario farm. Epidemiol. Infect., 120:17-20.


NAC No.: 12150563


Telephone:   613-966-8058
Order Desk:   800-265-5464
Fax:   613-966-4177
Fax Orders:   613-966-9485
Every effort has been made to ensure the accuracy of the Econiche information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert.

Copyright © 2018 North American Compendiums. Updated: 2018-02-26