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Cosequin Concentrated Powder

This page contains information on Cosequin Concentrated Powder for veterinary use.
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  • Cosequin Concentrated Powder Indications
  • Warnings and cautions for Cosequin Concentrated Powder
  • Direction and dosage information for Cosequin Concentrated Powder

Cosequin Concentrated Powder

This treatment applies to the following species:
Manufacturer: Nutramax

High Purity Glucosamine Hydrochloride & Low Molecular Weight Chondroitin Sulfate

For All Classes Of Horses


#1 Veterinarian Recommended Brand

Minimum Guaranteed Analysis

Each 3.3 Grams Contain:**


16 mg

Ascorbic Acid

104 mg

Glucosamine Hydrochloride*

1800 mg

Sodium Chondroitin Sulfate*

600 mg ***

Not recognized as an essential nutrient.


Glucosamine hydrochloride, microcrystalline cellulose, sodium chondroitin sulfate, manganese ascorbate.

** Each level scoop contains at least 3.3 grams.

*COSEQUIN® contains FCHG49® 99% Glucosamine Hydrochloride and TRH122® Low Molecular Weight 95% Sodium Chondroitin Sulfate, Nutramax Laboratories® exclusive veterinary researched specifications.

*** Reported on a hydrous basis.

Store in a cool, dry area out of direct sunlight. Keep lid tightly secured to ensure freshness.

This container contains (1) non-toxic desiccant to help preserve freshness and ensure the shelf life of the product.

Source: Surveys conducted in the Fall of 2002 and March 2004 of equine veterinarians who recommended oral joint health supplements.

Cosequin® Is Superior To Other Joint Health Supplements.

It Is The #1 Veterinarian Recommended Brand And The Only Brand Shown Effective, Safe, And Bioavailable In Horses In Published, Controlled U.s. Studies.

What Is Cosequin® Equine Powder?

Cosequin is a patented, scientifically researched supplement dispensed by thousands of veterinarians to help horses maintain healthy joints. It is available in an easy to use powder.

The horse's joints are complex structures that must handle extreme weight loads on a very small surface area. Through normal aging or wear and tear, it is common for the joints to become less flexible which impacts a horse's ability to perform. You may have noticed that your horse's stride has changed or he/she does not seem as limber as usual. Even at younger ages some horses, especially those engaged in strenuous exercise, are subject to joint health concerns which affect flexibility and mobility.

Cosequin provides vital components which facilitate the production of cartilage. It is an exclusive formula of three ingredients: TRH122®* low molecular weight chondroitin sulfate, FCHG49®*glucosamine hydrochloride, and manganese ascorbate. These ingredients have been scientifically formulated to support and maintain the health of your horse's joints. Published studies have shown that the specific combination of ingredients in Cosequin works together to maintain the structure of the cartilage while inhibiting the enzymes that break down cartilage. Cosequin is the only glucosamine/chondroitin sulfate brand shown to be effective, safe, and bioavailable in horses in published, controlled U.S. studies.1-5

What Is Joint Cartilage?

Cartilage is a slippery and resilient tissue produced and maintained by its own specialized cells. It cushions the surfaces where two or more bones form a flexible joint. When a horse is in motion there is tremendous pressure in the joint. Cartilage, joint fluid, and underlying bone work together like a shock absorber allowing flexible joint function. Because cartilage lacks a direct blood supply, nutrients must pass into the cartilage from surrounding tissue. These nutrients sustain cartilage cells and provide the components necessary to maintain a healthy cartilage structure. With age, injury, or over-activity, cartilage cannot maintain the proper balance in metabolic activity, and destructive processes overtake normal rebuilding processes. That's when it's time for Cosequin. The components of Cosequin work together to both enhance the synthesis of cartilage components as well as inhibit the enzymes that break down cartilage, thus restoring balance.

When Should I Start Giving My Horse Cosequin?

Early action is always the best advice. Most horseowners can detect subtle changes in their horse's gait before severe cartilage breakdown occurs. Unevenness in gait, reluctance to take or change a lead or shortness of stride are all early warnings of cartilage breakdown. Your first step is to have your horse examined by your veterinarian. Your veterinarian will advise you if Cosequin can help. Since horses place great stress on their cartilage, this often gets worse with time, but by using Cosequin early, you may be able to offset long-term problems. A study has shown some horses returned to competition after the second week of supplementation.1

How Long Does Cosequin Take To Work?

Cosequin is a nutritional supplement that works to gradually provide nutrients to maintain your horse's joint health. Following the administration schedule below for your horse's weight, we recommend an initial administration period of two to four weeks. Published research has reported improvement in some horses as early as two weeks. Following the initial administration period, the amount of Cosequin can be reduced to an economical maintenance schedule. (Please follow recommendations below for your horse's weight). Some liquid products claim to work within days. However, there are no published scientific studies to support these claims. If it sounds too good to be true, it probably is! Cosequin is available in powder form in 280g (84 scoops), 700g (212 scoops), and 1400g (424 scoops) containers. The 1400g size offers Cosequin's lowest price per scoop which will last well over six months at the maintenance level, (the number of scoops is based on 3.3 grams per scoop).

Directions For Administration

Simply add Cosequin Powder to your horse's feed following administration chart below. If your horse is not fed sweet feed, you can add a small amount of water or molasses to get the Cosequin to stick to the grain. You can also add molasses to appease a more finicky horse.


Initial 2-4 Weeks

Economical Long-term Administration

Under 600 lbs

2 scoops in AM
& 2 scoops in PM

1 Scoop Daily

600-1200 lbs

3 scoops in AM
& 3 scoops in PM

1-2 Scoops Daily

Over 1200 lbs

4 scoops in AM
& 4 scoops in PM

2 Scoops Daily

This chart should be used for guidance.

The initial administration is two to four weeks. Published research has reported improvement in some horses as early as two weeks. The amount of Cosequin can be increased during the initial administration period, if needed. If a horse shows little or no response after 30 days, extend the initial administration period for two more weeks.

Transition Period

Do not lower amount until horse begins to respond. After horse has achieved a good response, reduce daily administration by one level scoop each week. Gradually reducing the amount in this manner will help find a horse's individual maintenance level more easily. Always watch the horse's movement and attitude to ensure that he/she is still feeling comfortable through each weekly transition. The amount of Cosequin may be increased at any time.

Long-term Maintenance

Once consistent improvement has been seen, the maintenance level may be able to be reduced to every other day administration. Prior to and during an event or strenuous exercise, Cosequin administration can be increased up to the initial amount for maximum effect.

Using Cosequin For A Normal Horse

The maintenance level may also be used daily or even every other day on normal horses to help keep their joints healthy.

My Boarding Stable Limits Supplements To Once A Day. Can I Give All Of The Cosequin At One Time?

When necessary, the full amount may safely be given once daily. A safety study on horses has been completed with no noted adverse reactions.3

Is Cosequin Superior To Other Joint Supplements?

Yes! Cosequin, with its exclusive combination of high purity FCHG49® glucosamine, TRH122® low molecular weight chondroitin sulfate and manganese ascorbate, is the only glucosamine/chondroitin sulfate brand that has been shown safe, effective, and bioavailable in published, controlled U.S. studies. Other products may not use the same purity or quality of raw materials as Cosequin®; therefore, results of the published studies where Cosequin was used are not applicable to other products.

Cosequin is manufactured in the United States by Nutramax Laboratories® following manufacturing standards practiced by the pharmaceutical industry. Each batch of Cosequin is subjected to stringent quality control measures, including analysis of incoming raw materials and finished product. A study published in the Journal of the American Nutraceutical Association showed that over 80% of glucosamine/chondroitin human brands did not even meet their own label claim. Cosequin has been documented in scientific journals to meet label claim.

When you examine the label of other products they may appear to contain the same ingredients as Cosequin, but do they guarantee to meet labeled concentrations?

Chondroitin sulfate is a large molecule that is difficult to absorb. Cosequin is the only brand that uses the high purity, low molecular weight chondroitin sulfate that has been studied for absorption. Lower molecular weight means the particle size of the molecule is smaller and more easily absorbed by the digestive system than other less pure forms of chondroitin sulfate. While this form of chondroitin sulfate is more expensive, it is the only one supported by published, controlled U.S. clinical studies for efficacy, safety and absorption.

Other products that are labeled to contain chondroitin sulfate may actually use ground up shark cartilage or other less pure material. Many other products contain ingredients from sources that may not maintain strict quality control standards for purity and freedom from contamination.

Cosequin Concentrated Powder also contains FCHG49® glucosamine hydrochloride, which is greater than 99% pure! Glucosamine hydrochloride delivers significantly more bioavailable glucosamine than an equivalent amount of glucosamine sulfate.

In summary, the purity, superior absorption and bioavailability of Cosequin's trademarked ingredients, guaranteed to be as stated on the label, make Cosequin the true economical choice!

I Understand That Cosequin Is The Superior Glucosamine/chondroitin Sulfate Supplement Proven Effective In Numerous Published Studies, But My Horse Is Taking Supplements Containing Yucca, Msm, Amino Acids Or Perna Mussel. Do I Still Need Cosequin?

None of these compounds has ever been shown in published studies to affect joint cartilage. Some of these materials may have a mild effect on your horse's discomfort but will not get to the "root-of the problem" and may only be a temporary "band-aid". Cosequin has been shown to significantly enhance the function of your horse's joints.1,2 Cosequin also has been shown to stimulate cartilage cells and protect cartilage from further breakdown. No other glucosamine/chondroitin, yucca, MSM, amino acid, or perna mussel product has extensive published research to support these claims.

Are There Any Side Effects?

Cosequin offers unparalleled safety. Overdose safety studies have been conducted in horses with no adverse findings.6

Can It Be Given To A Pregnant Mare?

No studies have been completed that specifically address the use of Cosequin during pregnancy. Use during pregnancy should be an individual decision in consultation with your veterinarian.

Can Cosequin Be Used On A Competition Day?

Cosequin contains only natural ingredients normally found in the horse's body and therefore cannot be tested like foreign substances. However, it is best to check with the appropriate authority for its regulations concerning supplements.

Is Cosequin Cost Effective?

Yes! As your horse's performance improves, the daily amount of Cosequin may be reduced to an economical maintenance level. This level may be as low as one scoop per day or every other day.

When I'm Riding I Put A Lot Of Stress On My Own Joints. Is There A Nutramax Laboratories Product For Me?

Yes. Nutramax Laboratories makes Cosamin®DS, the orthopedic surgeon and rheumatologist #1 recommended brand.6 Like its veterinary counterpart, CosaminDS uses the same quality materials and is manufactured following standards practiced by the pharmaceutical industry. CosaminDS is the glucosamine/chondroitin sulfate brand proven effective in peer-reviewed controlled, clinical studies conducted and published in the U.S.6 Recently, the Physicians Desk Reference (PDR) for Nutritional Supplements stated, "More recent studies demonstrate that there is probably significant absorption of low molecular weight chondroitin sulfate." Nutramax Laboratories' products Cosequin and CosaminDS are the only brands that use the high purity, low molecular weight chondroitin sulfate referred to in the PDR.

1. Hanson RR, Smalley LR, Huff GK, et al. Equine Practice 19(9):16-22, 1997.

2. Hanson RR, Brawner WR, Blaik MA, et al. Veterinary Therapeutics 2(2):148-159, 2001.

3. Kirker-Head CA, Kirker-Head RP. Veterinary Therapeutics 2(4):345-353, 2001.

4. Du J, White N, Eddington ND. Biopharmaceutics and Drug Disposition 25(3):109-116, 2004.

5. Orth MW, Peters TL, Hawkins JN. Equine Veterinary Journal Suppl. (34):224-229, 2002.

6. Sources: Surveys conducted by Orthopedics Today of orthopedic surgeons and rheumatologists in April 2000, November 2001, and July 2003 relating to glucosamine/chondroitin sulfate brands. Clinical studies published in Military Medicine, 1999, and Osteoarthritis and Cartilage, 2000.

U.S. PATENT NO. 5,587,363

The Nutraceutical Company



(based on 3.3 grams per scoop)




280 GRAMS (.62 LBS.)



700 GRAMS (1.54 LBS.)



1400 GRAMS (3 LBS.)


Nac No.

Telephone:   410-776-4000
Toll-Free:   800-925-5187
Fax:   410-776-4009
Every effort has been made to ensure the accuracy of the Cosequin Concentrated Powder information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Cosequin Concentrated Powder product label or package insert.

Copyright © 2018 North American Compendiums. Updated: 2018-01-04